Gene News and Research

Latest Gene News and Research

Using deep learning to analyze genetic mutations: an interview with Brendan Frey

To understand deep learning in the context of genetic disease, you need to understand shallow learning first. Shallow learning relates mutations to diseases by looking for mutations that commonly occur in patients with a disease. It’s a commonly used method.

21 Sep 2015

Satellite DNA plays vital regulatory role in how organisms adapt to environmental changes

A team of geneticists led by Prof. Đurđica Ugarković of the Croatian Ruđer Bošković Institute have for the first time proved that satellite DNA plays an important regulatory role in how organisms adapt to stressful changes in their environment. These results could in the future help scientists explain how an organism successfully survives stress.

21 Sep 2015

Abnormal behaviour of BDNF and DTNBP1 genes linked to underlying cause of schizophrenia

Research led by scientists from Duke-NUS Graduate Medical School Singapore (Duke-NUS) has linked the abnormal behaviour of two genes (BDNF and DTNBP1) to the underlying cause of schizophrenia. These findings have provided a new target for schizophrenia treatment.

21 Sep 2015

New study finds link between maternal protein deficiency during pregnancy and metabolic diseases in offspring

A new study has uncovered the genetic processes that link insufficient protein consumption during pregnancy with the development of muscle problems in mothers and their male offspring.

19 Sep 2015

Thomas Jefferson University provides routine genomic fingerprinting to cancer patients

Cancer medicine is moving towards understanding what drives each particular patient's cancer. But not every patient has had access to this level of individualized care.

18 Sep 2015

Study confirms pathogenic role of beta amyloid in dementia as seen in AD and Down syndrome

More than five million Americans are living with Alzheimer's disease (AD). Of them, 400,000 also have Down syndrome. Both groups have similar looking brains with higher levels of the protein beta amyloid.

18 Sep 2015

Researchers identify triple mechanism that prevents onset of chromosomal instability

Universitat Autònoma de Barcelona researchers have identified for the first time the triple mechanism that stops chromosome separation in response to situations that compromise the integrity of the genetic information. The loss of this response capacity is characteristic of cancerous cells.

18 Sep 2015

Quethera receives seed investment funding to develop gene therapy for glaucoma

Quethera, a gene therapy company developing a treatment for glaucoma that could prevent blindness, has received seed investment funding led by Midven’s Rainbow Seed Fund alongside co-investor Cambridge Enterprise, the commercialisation arm of the University of Cambridge, to continue pre-clinical development of their therapy.

18 Sep 2015

CEVEC partners with Généthon to develop lentivirus packaging cell lines based on its CAP GT technology

CEVEC Pharmaceuticals GmbH, the expert in the production of tailor-made recombinant glycoproteins and gene therapy vectors, today announced a collaboration agreement with Généthon (Evry, France) for the development and exploitation of lentivirus packaging cell lines based on CEVEC’s proprietary CAP GT technology.

18 Sep 2015

Cancer-causing gene disrupts internal rhythm, metabolic pathways in cancer cells

Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells, found a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Postdoctoral fellow Brian Altman, PhD, and doctoral student Annie Hsieh, MD, both from the lab of senior author Chi Van Dang, MD, PhD, director Abramson Cancer Center, study body clock proteins associated with cancer cells.

18 Sep 2015

New optimising ChIP sequencing library preparation guide

Chromatrap®, a business unit of Porvair Sciences, has produced an informative new guide entitled ‘Top 10 Tips for ChIP-seq Library Preparation'.

From Chromatrap® - Porvair Sciences Ltd 18 Sep 2015

CardioDx announces national agreement with Quest Diagnostics to expand access to Corus CAD blood test

CardioDx, Inc., a molecular diagnostics company specializing in cardiovascular genomics, today announced a national specimen-draw agreement with Quest Diagnostics DGX, +1.23% the world's leading provider of diagnostic information services, that will expand patient and clinician access to the Corus CAD lab-developed blood test for aiding the assessment of obstructive coronary artery disease (CAD).

From Quest Diagnostics 18 Sep 2015

Benitec Biopharma initiates new site for ongoing Phase 1/2a TT-034 trial for hepatitis C

Benitec Biopharma Limited, a clinical-stage biotechnology company developing innovative therapeutics based on its gene-silencing technology, DNA-directed RNA interference (ddRNAi), is pleased to announce it has initiated a new site for its ongoing Phase 1/2a TT-034 trial at the Methodist Health System Clinical Research Institute in Dallas, Texas.

16 Sep 2015

WuXi NextCODE, CHFU partner to advance precision medicine in China

WuXi NextCODE, a precision medicine company using the genome to improve health worldwide, and the Children's Hospital of Fudan University, based in Shanghai and serving 2.3 million patients nationwide per year, today announced the signing of a landmark agreement for advancing precision medicine in China.

16 Sep 2015

New Penn Medicine research shows vital role of Esrp1 and Esrp2 genes in skin, organ development

Knocking out one or both crucial regulatory genes caused cleft lip, skin barrier defects, and a host of other developmental problems in mice, according to new research from the Perelman School of Medicine at the University of Pennsylvania, hinting that abnormalities in these molecular pathways could underlie many birth defects that are presently not well understood. The two closely related regulatory genes are active in the normal development of mammals and govern how RNAs produced from the genes are joined to make final versions of the encoded protein, a process called alternative splicing.

16 Sep 2015

Scientists find how cells adapt to overcome cancer drugs

CANCER RESEARCH UK scientists have found how cells adapt to overcome cancer drugs designed to interfere with their genetic controls, according to a study published today (Wednesday) in Epigenetics and Chromatin.

16 Sep 2015

Healthy diet and exercise can protect against AMD

People with a genetic predisposition for age-related macular degeneration (AMD) significantly increased their odds of developing the blinding eye disorder if they had a history of heavy smoking and consistently did not exercise or eat enough fruits and vegetables, according to an observational study of women funded by the National Eye Institute, part of the National Institutes of Health.

16 Sep 2015

New whitepaper describes benefits of using OGT’s CytoSure Medical Research Exome Array in genetic research

Oxford Gene Technology, The Molecular Genetics Company, has been speaking to genetic scientists, Dr Tracey Lewis (Associated Regional and University Pathologists Laboratories) and Dr Emily Farrow (Children’s Mercy Hospital), in a new whitepaper entitled “Examining the Medical Exome”.

From Oxford Gene Technology 15 Sep 2015

Researchers discover new gene that could be a potential therapeutic target for muscle wasting

It is estimated that half of all cancer patients suffer from a muscle wasting syndrome called cachexia. Cancer cachexia impairs quality of life and response to therapy, which increases morbidity and mortality of cancer patients. Currently, there is no approved treatment for muscle wasting but a new study from the Research Institute of the McGill University Health Centre and University of Alberta could be a game changer for patients, improving both quality of life and longevity.

15 Sep 2015

Study reveals how leukemia cells evade deadly effects of BRD4 inhibitors

BRD4 inhibitors are among the most promising new agents in cancer therapy that are currently evaluated in clinical trials.

15 Sep 2015

Gene News and Research

Latest Gene News and Research

Using deep learning to analyze genetic mutations: an interview with Brendan Frey

Satellite DNA plays vital regulatory role in how organisms adapt to environmental changes

Abnormal behaviour of BDNF and DTNBP1 genes linked to underlying cause of schizophrenia

New study finds link between maternal protein deficiency during pregnancy and metabolic diseases in offspring

Thomas Jefferson University provides routine genomic fingerprinting to cancer patients

Study confirms pathogenic role of beta amyloid in dementia as seen in AD and Down syndrome

Researchers identify triple mechanism that prevents onset of chromosomal instability

Quethera receives seed investment funding to develop gene therapy for glaucoma

CEVEC partners with Généthon to develop lentivirus packaging cell lines based on its CAP GT technology

Cancer-causing gene disrupts internal rhythm, metabolic pathways in cancer cells

New optimising ChIP sequencing library preparation guide

CardioDx announces national agreement with Quest Diagnostics to expand access to Corus CAD blood test

Benitec Biopharma initiates new site for ongoing Phase 1/2a TT-034 trial for hepatitis C

WuXi NextCODE, CHFU partner to advance precision medicine in China

New Penn Medicine research shows vital role of Esrp1 and Esrp2 genes in skin, organ development

Scientists find how cells adapt to overcome cancer drugs

Healthy diet and exercise can protect against AMD

New whitepaper describes benefits of using OGT’s CytoSure Medical Research Exome Array in genetic research

Researchers discover new gene that could be a potential therapeutic target for muscle wasting

Study reveals how leukemia cells evade deadly effects of BRD4 inhibitors

eBook: Using iPSCs models for human disease research and drug discovery eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich