Gene News and Research

Latest Gene News and Research

Genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells

A genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells, Johns Hopkins scientists report. Unlike many known disease-linked variants, this one lies not in a gene but in so-called noncoding DNA, a growing focus of disease research.

28 May 2014

Findings may help medical researchers identify effective drug targets for triple negative breast cancer

The suppression of two genes reduce breast cancer tumor formation and metastasis by interfering with blood vessel formation and recruitment, report scientists from Houston Methodist and five other institutions in the Proceedings of the National Academy of Sciences (now online).

28 May 2014

Study detects hormone receptor's key role in normal organ development and function

A discovery by UC Irvine endocrinologists about the importance of cell surface receptors for estrogen has the potential to change how researchers view the hormone's role in normal organ development and function.

28 May 2014

Study reveals loss of function of gene RARRES3 in breast cancer cells promotes metastasis to lung

A study published today in EMBO Molecular Medicine reveals that the loss of function of the gene RARRES3 in breast cancer cells promotes metastasis to the lung.

28 May 2014

Researchers develop new technology that uses HIV virus as tool to fight against hereditary diseases

For the first time researchers have succeeded in altering HIV virus particles so that they can simultaneously, as it were, 'cut and paste' in our genome via biological processes. Developed at the Department of Biomedicine at Aarhus University, the technology makes it possible to repair genomes in a new way.

28 May 2014

Twist Bioscience raises $26M in Series B financing, receives $5.1M DARPA contract

Twist Bioscience today announced that it raised $26 million in a Series B financing to commercialize the company's semiconductor-based synthetic gene manufacturing process.

27 May 2014

Nationwide Insurance Foundation donates $10M to Nationwide Children's Hospital

Nationwide Children's Hospital today announced that it has received a $10 million gift from the Nationwide Insurance Foundation.

27 May 2014

New study of how biodiversity arises

A new study of how biodiversity arises, by evolutionary biologists at the University of Massachusetts Amherst, shows how a mutation in a single gene during development can lead to different consequences not only in how animals' skull and jaw are shaped, but how this leads to different feeding strategies to exploit different ecological niches.

27 May 2014

Inovio announces positive results on DNA-based monoclonal antibody therapy targeting CHIKV

Inovio Pharmaceuticals, Inc. announced today that its novel DNA-based therapeutic monoclonal antibody targeting Chikungunya virus (CHIKV) completely protected mice from a lethal CHIKV challenge.

27 May 2014

Researchers discover signaling pathway in cancer cells that invades nearby tissues

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a signaling pathway in cancer cells that controls their ability to invade nearby tissues in a finely orchestrated manner.

26 May 2014

Researchers identify mutated gene common to rare form of pancreatic cancer

Researchers at the University of California, San Diego School of Medicine have identified a mutated gene common to adenosquamous carcinoma (ASC) tumors - the first known unique molecular signature for this rare, but particularly virulent, form of pancreatic cancer.

26 May 2014

Study: Sufficient copies of SMN1 gene extend survival in animals with spinal muscular atrophy

To make up for insufficient amounts of SMN protein, the cause of the inherited neuromuscular disease spinal muscular atrophy (SMA), researchers have successfully delivered a replacement SMN1 gene directly to the spinal cords of animal models of SMA.

23 May 2014

Inovio Pharmaceuticals proposes 1-for-4 reverse split of common stock

Inovio Pharmaceuticals, Inc. today announced that at the Company's Annual General Meeting held May 22, 2014, the Company's shareholders approved the proposal of a reverse split of the Company's common stock.

23 May 2014

Immucor's PreciseType HEA test receives FDA approval to predict blood compatibility

Immucor, Inc., a global leader in transfusion and transplantation diagnostics, announced that the U.S. Food and Drug Administration has granted approval for the company's PreciseType HEA test.

23 May 2014

EMA's CHMP gives positive opinion for PTC Therapeutics' Translarna

PTC Therapeutics, Inc. today announced that following its request for re-examination, the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion regarding the company's application for a conditional marketing authorization of Translarna (ataluren) for the treatment of nonsense mutation Duchenne muscular dystrophy (nmDMD) in ambulatory patients aged five years and older.

23 May 2014

Researchers discover how gene commonly linked to obesity contributes to weight gain

Researchers have discovered how a gene commonly linked to obesity—FTO—contributes to weight gain. The study shows that variations in FTO indirectly affect the function of the primary cilium, a little-understood hair-like appendage on brain and other cells.

23 May 2014

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Researchers at the University of Maryland School of Medicine have identified a mutation in a fat-storage gene that appears to increase the risk for type 2 diabetes and other metabolic disorders, according to a study published online today in the New England Journal of Medicine.

23 May 2014

Researchers resolve long-standing mystery of enzyme's role in cell survival

St. Jude Children's Research Hospital solves mystery of enzyme's role in cell survival, offering clues of how immune system fights infection and possible strategies to treat problems ranging from heart attack to cancer.

23 May 2014

Researchers uncover potential vaccine that can stop malaria parasites from multiplying

Researchers have identified a substance, or antigen, that generates antibodies that can hinder the ability of malaria parasites to multiply, which may protect against severe malaria infection.

23 May 2014

New database allows researchers to match old drugs for new diseases

There are thousands of drugs that silence many thousands of cancer-causing genetic abnormalities. Some of these drugs are in use now, but many of these drugs are sitting on shelves or could be used beyond the disease for which they were originally approved.

23 May 2014

Gene News and Research

Latest Gene News and Research

Genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells

Findings may help medical researchers identify effective drug targets for triple negative breast cancer

Study detects hormone receptor's key role in normal organ development and function

Study reveals loss of function of gene RARRES3 in breast cancer cells promotes metastasis to lung

Researchers develop new technology that uses HIV virus as tool to fight against hereditary diseases

Twist Bioscience raises $26M in Series B financing, receives $5.1M DARPA contract

Nationwide Insurance Foundation donates $10M to Nationwide Children's Hospital

New study of how biodiversity arises

Inovio announces positive results on DNA-based monoclonal antibody therapy targeting CHIKV

Researchers discover signaling pathway in cancer cells that invades nearby tissues

Researchers identify mutated gene common to rare form of pancreatic cancer

Study: Sufficient copies of SMN1 gene extend survival in animals with spinal muscular atrophy

Inovio Pharmaceuticals proposes 1-for-4 reverse split of common stock

Immucor's PreciseType HEA test receives FDA approval to predict blood compatibility

EMA's CHMP gives positive opinion for PTC Therapeutics' Translarna

Researchers discover how gene commonly linked to obesity contributes to weight gain

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Researchers resolve long-standing mystery of enzyme's role in cell survival

Researchers uncover potential vaccine that can stop malaria parasites from multiplying

New database allows researchers to match old drugs for new diseases

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