Gene News and Research

Latest Gene News and Research

Amgen appeals EMA CHMP negative opinion on Vectibix-chemotherapy combination for wild-type KRAS mCRC

Amgen announced today that it has submitted a request to the European Medicines Agency (EMA) for a re-examination of the negative opinion issued in March by the Committee For Medicinal Products for Human Use (CHMP) for the use of Vectibix in combination with chemotherapy for patients with wild-type KRAS metastatic colorectal cancer (mCRC).

31 Mar 2011

20-year data shows bariatric surgery to reduce risk of heart attack and stroke in diabetics

In the longest study of its kind, bariatric surgery has been shown to reduce the risk of heart attack and stroke in patients with diabetes. These results and other groundbreaking research were presented at the 2nd World Congress on Interventional Therapies for Type 2 Diabetes, hosted by NewYork-Presbyterian Hospital and Weill Cornell Medical College.

31 Mar 2011

Amyloid plaques in normal older individuals may be early signs of Alzheimer's

Researchers using two brain-imaging technologies have found that apparently normal older individuals with brain deposits of amyloid beta - the primary constituent of the plaques found in the brains of Alzheimer's disease patients - also had changes in brain structure similar to those seen in Alzheimer's patients.

31 Mar 2011

Regulus obtains exclusive rights from NYU for miR-33a, 33b to treat metabolic diseases

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative new medicines targeting microRNAs, today announced that it has obtained exclusive rights from New York University for intellectual property covering methods of use in modulating microRNA-33a and microRNA-33b for metabolic diseases such as atherosclerosis and metabolic syndrome.

31 Mar 2011

Study provides insight into kidney cancer

Researchers at UT Southwestern Medical Center have discovered genetic pathways to starve selectively kidney cancer cells.

31 Mar 2011

Gilead and Yale enter multi-year cancer research collaboration

Gilead Sciences, Inc. and Yale School of Medicine today announced the formation of a multi-year research collaboration focused on the discovery of novel cancer therapies. The research effort will initially span four years with an option to renew for up to ten years.

30 Mar 2011

Merck submits Erbitux indication extension to EMA for NSCLC treatment

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, announced today that it has submitted an indication extension to the European Medicines Agency for the approval of Erbitux in combination with standard 1st line platinum-based chemotherapy in patients with advanced or metastatic non-small cell lung cancer with high epidermal growth factor receptor expression.

30 Mar 2011

Positive results from Vertex VX-770 Phase 3 trial against CF

Vertex Pharmaceuticals Incorporated today announced positive results from a 24-week analysis of the ongoing Phase 3 ENVISION study of VX-770, an oral medicine in development that targets the defective protein that causes cystic fibrosis.

30 Mar 2011

SHMT1 gene and folate deficiency increase risk for colon cancer

Offering a likely insight into how such cancers develop in humans - Cornell University researchers report they have identified a gene that increases the risk for colon cancer in laboratory mice when the animals' diets are deficient in folate.

30 Mar 2011

Study: Gene combinations may increase risk of hip osteoporosis in women

Women with osteoporosis in their hip suffer menopause two years earlier than healthy women, a study conducted at the University of Granada says. Additionally, although further study is required, researchers have found at least three genetic markers associated with osteoporosis in the hip in postmenopausal women.

30 Mar 2011

Labcyte launches 1536-well tissue-culture treated microplate for cell-based screening

Labcyte Inc. today launched a new 1536-well tissue-culture treated microplate for cell-based screening and discovery applications. By enabling cell culture directly in a high-density microplate, this new product expands cell-based assay miniaturization capabilities, such as direct PCR from cell cultures.

30 Mar 2011

Australian researchers say the search must widen for genes that cause heart defects in babies

Australian scientists have discovered a new group of genes that could be responsible for causing heart defects in children, which affect more than 2000 babies born each year in Australia.

29 Mar 2011

Bariatric surgery highly cost-effective treatment for obese type 2 diabetics

Bariatric surgery is an especially cost-effective therapy for managing Type 2 diabetes in moderately and severely obese patients. These findings and others were presented today at the 2nd World Congress on Interventional Therapies for Type 2 Diabetes, hosted by NewYork-Presbyterian Hospital and Weill Cornell Medical College.

29 Mar 2011

Scientists to discover new estrogen receptor-signaling networks for breast cancer treatment

The quandary of breast cancer in women is deep: the female hormone, estrogen, is considered to be a quasi-fuel for developing breast cancer.

29 Mar 2011

Study: Donor's DNA level in heart transplant recipient's blood can reveal organ rejection

Heart transplant recipients and their physicians are likely more concerned with the function of the donated organ than with the donor's DNA sequences that tag along in the new, healthy tissue.

29 Mar 2011

Genetic link to attempted suicide discovered - Findings could lead to new avenues of treatment

Johns Hopkins scientists, reporting in the journal Molecular Psychiatry, have identified a small region on chromosome 2 that is associated with increased risk for attempted suicide. This small region contains four genes, including the ACP1 gene, and the researchers found more than normal levels of the ACP1 protein in the brains of people who had committed suicide. This protein is thought to influence the same biological pathway as lithium, a medication known to reduce the rate of suicidal behavior.

28 Mar 2011

Everist Genomics announces global launch of OncoDefender-CRC colorectal cancer assay

Everist Genomics today announced the worldwide commercial availability of its OncoDefender-CRC colorectal cancer assay, the first and only molecular prognostic test capable of accurately predicting the risk of recurrence of cancer in patients previously treated with surgical resection of a Stage I/II colon cancer tumor or Stage I rectal cancer tumor.

28 Mar 2011

WaferGen launches SmartChip Human microRNA Panel V2 for gene expression profiling

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genomic analysis systems, today announced the launch of its industry-leading SmartChip Human microRNA Panel V2 for gene expression profiling on the SmartChip Real-Time PCR System.

28 Mar 2011

Metagenics announces 2011 schedule for educational programs in lifestyle medicine

Metagenics Inc., a nutrigenomics and lifestyle medicine company dedicated to reducing chronic illness and improving health, announced today the 2011 schedule for educational programs in lifestyle medicine as well as for certification programs for its FirstLine Therapy, a turnkey, lifestyle medicine program.

28 Mar 2011

MolecularMD and ARIAD collaborate to develop and commercialize CML, ALL diagnostic test

ARIAD Pharmaceuticals, Inc. and MolecularMD Corporation today announced an exclusive collaboration agreement in which MolecularMD will develop and commercialize a companion diagnostic test to identify the T315I mutation of the BCR-ABL gene in patients with chronic myeloid leukemia and Philadelphia positive acute lymphoblastic leukemia.

28 Mar 2011

Gene News and Research

Latest Gene News and Research

Amgen appeals EMA CHMP negative opinion on Vectibix-chemotherapy combination for wild-type KRAS mCRC

20-year data shows bariatric surgery to reduce risk of heart attack and stroke in diabetics

Amyloid plaques in normal older individuals may be early signs of Alzheimer's

Regulus obtains exclusive rights from NYU for miR-33a, 33b to treat metabolic diseases

Study provides insight into kidney cancer

Gilead and Yale enter multi-year cancer research collaboration

Merck submits Erbitux indication extension to EMA for NSCLC treatment

Positive results from Vertex VX-770 Phase 3 trial against CF

SHMT1 gene and folate deficiency increase risk for colon cancer

Study: Gene combinations may increase risk of hip osteoporosis in women

Labcyte launches 1536-well tissue-culture treated microplate for cell-based screening

Australian researchers say the search must widen for genes that cause heart defects in babies

Bariatric surgery highly cost-effective treatment for obese type 2 diabetics

Scientists to discover new estrogen receptor-signaling networks for breast cancer treatment

Study: Donor's DNA level in heart transplant recipient's blood can reveal organ rejection

Genetic link to attempted suicide discovered - Findings could lead to new avenues of treatment

Everist Genomics announces global launch of OncoDefender-CRC colorectal cancer assay

WaferGen launches SmartChip Human microRNA Panel V2 for gene expression profiling

Metagenics announces 2011 schedule for educational programs in lifestyle medicine

MolecularMD and ARIAD collaborate to develop and commercialize CML, ALL diagnostic test

eBook: Using iPSCs models for human disease research and drug discovery eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering