Gene News and Research

Latest Gene News and Research

Study reveals underlying molecular mechanism contributing to development of lymphomagenesis

Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have discovered a new potential therapeutic target for Diffuse Large B-Cell Lymphoma (DLBCL), the most aggressive and common type of lymphoma in adults.

29 Nov 2011

Critical breakthrough in development of treatment for Duchenne Muscular Dystrophy

Academics from Royal Holloway, University of London and a team lead by scientists at the UCL Institute of Child Health (ICH), have made an important breakthrough in the development of a treatment for Duchenne Muscular Dystrophy (DMD) which in the future could help the likes of the Lloyd family who were featured on last night's X-Factor show.

29 Nov 2011

Scientists use genetic methods to successfully repair cleft lips in mice embryos

Scientists at Weill Cornell Medical College used genetic methods to successfully repair cleft lips in mice embryos specially engineered for the study of cleft lip and cleft palate. The research breakthrough may show the way to prevent or treat the conditions in humans.

29 Nov 2011

New compound circumvents drug-efflux pumps associated with Gram-positive bacteria

It's no wonder that medicine's effort to combat bacterial infections is often described as an arms race. When new drugs are developed to combat infections, the bacterial target invariably comes up with a deterrent.

29 Nov 2011

Abbott, GSK expand collaboration to develop additional companion diagnostic test

Abbott announced today that it will expand its existing agreement with GlaxoSmithKline Biologicals S.A. to include the development of an additional companion diagnostic test in support of GSK's cancer immunotherapy research program.

29 Nov 2011

Genetic, lifestyle factors and HRT increase risk of breast cancer

The risk of breast cancer is increased by genetic and lifestyle factors such as the inherited BRCA2 gene, age of having first child, or use of hormone replacement therapy (HRT).

28 Nov 2011

Roche NimbleGen, BGI develop Major Histocompatibility Complex region capture technology

Roche NimbleGen, Inc. and BGI, the world's largest genomic organization, announced that they have developed a Major Histocompatibility Complex (MHC) region capture technology based on NimbleGen SeqCap EZ Choice Library, a revolutionary process for the enrichment of the MHC region.

28 Nov 2011

Rare syndrome's workings could help explain how brain wiring goes awry

Potential clues to how autism miswires the brain are emerging from a study of a rare, purely genetic form of the disorders that affects fewer than 20 people worldwide. Using cutting-edge "disease-in a-dish" technology, researchers funded by the National Institutes of Health have grown patients' skin cells into neurons to discover what goes wrong in the brain in Timothy Syndrome.

28 Nov 2011

Most people with Timothy syndrome mutation have autistic symptoms

Neuroscientists at Stanford University School of Medicine have homed in on potential differences in autistic people's brain cells by studying brainlike spheres grown in an elaborate process from skin cells.

28 Nov 2011

Even normal salt intake can cause hypertension in people suffering from sodium dysregulation

Hypertension is an endemic condition with far-reaching consequences. For instance, high blood pressure is the main cause of heart attacks and strokes. Other organs are also damaged by the chronic condition.

25 Nov 2011

Scientists decode how Machado-Joseph disease arises

Neurodegenerative diseases represent one of the greatest challenges of our aging society. However, investigation into these diseases is made particularly difficult due to the limited availability of human brain tissue. Scientists from the Life & Brain Research Center and Neurology Clinic of Bonn University have now taken a roundabout path: They reprogrammed skin cells from patients with a hereditary movement disorder into so-called induced pluripotent stem cells (iPS cells) and obtained functional nerve cells from them.

24 Nov 2011

Dantrolene reduces severity of walking and balance problems linked with HD

Huntington's disease (HD) is characterized by ongoing destruction of specific neurons within the brain. It affects a person's ability to walk, talk, and think - leading to involuntary movement and loss of muscle co-ordination. New research published in BioMed Central's open access journal Molecular Neurodegeneration shows that the RyanR inhibitor Dantrolene is able to reduce the severity of walking and balance problems in a mouse model of HD.

24 Nov 2011

ABCC9 gene also influences duration of sleep in humans

A collaborative European study led by LMU researchers has shown that ABCC9, a known genetic factor in heart disease and diabetes, also influences the duration of sleep in humans.

24 Nov 2011

Scientists discover genetic mechanism behind finger malformation

Scientists from the EPFL and the University of Geneva have discovered a genetic mechanism that defines the shape of our members in which, surprisingly, genes play only a secondary role. The research published in Cell, online the 23rd of November, shows the mechanism is found in a DNA sequence that was thought, incorrectly, to play no role.

24 Nov 2011

MC3R gene plays an important role in maintaining steady weight

Against the backdrop of the growing epidemic of obesity in the United States, scientists from the Florida campus of The Scripps Research Institute have made an important new discovery regarding a specific gene that plays an important role in keeping a steady balance between our food intake and energy expenditure. The study may help scientists better understand the keys to fighting obesity and related disorders such as diabetes.

24 Nov 2011

Uncommon genetic deletions associated with short stature

New research sifts through the entire genome of thousands of human subjects to look for genetic variation associated with height. The results of the study, published by Cell Press in the December issue of the American Journal of Human Genetics, suggest that uncommon genetic deletions are associated with short stature.

24 Nov 2011

Knocking out one copy of IGF1 receptor fails to increase life span of male mice

Scientists studying longevity thought it might be good to lack a copy of a gene, called IGF1 receptor, that is important in insulin signaling. Previous studies showed invertebrates that lacked the copy lived longer, even if their bodies were less responsive to insulin, the hormone that lowers blood sugar.

24 Nov 2011

Metformin prevents growth of breast cancer cells in human cultures

An inexpensive drug that treats Type-2 diabetes has been shown to prevent a number of natural and man-made chemicals from stimulating the growth of breast cancer cells, according to a newly published study by a Michigan State University researcher.

24 Nov 2011

Scientists identify MEGF10 defective gene responsible for muscle weakness

An international team of researchers from England and the Charité - Universitätsmedizin Berlin has presented new findings regarding the function of muscle stem cells, which are published in the current issue of the journal Nature Genetics.

23 Nov 2011

Advaxis completes ADXS-HER2 pre-IND meeting with FDA

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, completed a pre-IND meeting with the FDA on November 22, 2011 to discuss the development plan for ADXS-HER2, an immunotherapy for the treatment of HER2 expressing cancers.

23 Nov 2011

Gene News and Research

Latest Gene News and Research

Study reveals underlying molecular mechanism contributing to development of lymphomagenesis

Critical breakthrough in development of treatment for Duchenne Muscular Dystrophy

Scientists use genetic methods to successfully repair cleft lips in mice embryos

New compound circumvents drug-efflux pumps associated with Gram-positive bacteria

Abbott, GSK expand collaboration to develop additional companion diagnostic test

Genetic, lifestyle factors and HRT increase risk of breast cancer

Roche NimbleGen, BGI develop Major Histocompatibility Complex region capture technology

Rare syndrome's workings could help explain how brain wiring goes awry

Most people with Timothy syndrome mutation have autistic symptoms

Even normal salt intake can cause hypertension in people suffering from sodium dysregulation

Scientists decode how Machado-Joseph disease arises

Dantrolene reduces severity of walking and balance problems linked with HD

ABCC9 gene also influences duration of sleep in humans

Scientists discover genetic mechanism behind finger malformation

MC3R gene plays an important role in maintaining steady weight

Uncommon genetic deletions associated with short stature

Knocking out one copy of IGF1 receptor fails to increase life span of male mice

Metformin prevents growth of breast cancer cells in human cultures

Scientists identify MEGF10 defective gene responsible for muscle weakness

Advaxis completes ADXS-HER2 pre-IND meeting with FDA

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research