Gene News and Research

Latest Gene News and Research

MHRA extends the license of two cystic fibrosis drugs for children aged two to five years old

The Medicines and Healthcare products Regulatory Agency (MHRA) has today (15 November 2023) extended the licence of the cystic fibrosis medicines Kaftrio (ivacaftor, tezacaftor and elexacaftor) and Kalydeco (ivacaftor) for children aged two to five years old.

20 Nov 2023

Avian influenza A H5N1 virus impacts wide range of wildlife in the U.S., study shows

Study highlights the spread of the highly pathogenic avian influenza A (H5N1) virus among non-domesticated animals in the U.S., revealing neurological symptoms as a key clinical presentation and expanding the range of species affected by this Eurasian lineage virus.

19 Nov 2023

New understanding of lung cancer cells' 'memories' suggests novel treatment approach

A new understanding of lung cancer cells' "memories" suggests a new strategy for improving treatment, Memorial Sloan Kettering Cancer Center (MSK) researchers have found.

17 Nov 2023

Complex genetics behind human cranial vault shape revealed

Researchers at the University of Pittsburgh and KU Leuven have discovered a suite of genes that influence head shape in humans.

17 Nov 2023

Experts shed light on how autism affects the diagnosis, treatment of epilepsy and vice versa

Compared with the general population, epilepsy is more common in people with autism - and autism is more common in people with epilepsy. How can autism affect the diagnosis and treatment of epilepsy, and vice versa? Joy Mazur spoke to Dr. Colin Reilly and Dr. Stéphane Auvin.

17 Nov 2023

New insights into sporadic early-onset Alzheimer's disease

Alzheimer's disease (AD), the most prevalent neurodegenerative disease globally, poses a significant threat to human health.

17 Nov 2023

New method unveils the "imageable genome" for medical diagnostics

An international research group led by the University of Lucerne has developed novel approaches for medical imaging.

17 Nov 2023

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

16 Nov 2023

New insights into how cells maintain their identity over generations

Every cell in the human body contains the same genetic instructions, encoded in its DNA. However, out of about 30,000 genes, each cell expresses only those genes that it needs to become a nerve cell, immune cell, or any of the other hundreds of cell types in the body.

16 Nov 2023

Long-term monitoring of gene therapy patients crucial for safety, study says

Medical research has shown promising results regarding the potential of gene therapy to cure genetic conditions such as sickle cell disease and the findings of this study, published in Nature Medicine, offer important new insights into processes happening in the body after treatment.

16 Nov 2023

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated.

16 Nov 2023

Molecular trap offers hope for ALS treatment

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects neurons in the brain and spinal cord causing loss of muscle control.

16 Nov 2023

AI model predicts patient outcomes across multiple cancer types

Investigators from the UCLA Health Jonsson Comprehensive Cancer Center have developed an artificial intelligence (AI) model based on epigenetic factors that is able to predict patient outcomes successfully across multiple cancer types.

16 Nov 2023

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

The R136S genetic mutation protected against apolipoprotein E4 (APOE4)-induced late-onset Alzheimer’s disease (LOAD).

16 Nov 2023

One in five patients on Nirmatrelvir–Ritonavir experience virologic rebound, new observational study reveals

The frequency of viral rebound (VR) among acute coronavirus disease 2019 patients.

16 Nov 2023

Researchers discover genetic mechanism behind pancreatic cancer metastasis

Pancreatic cancer is tricky to manage because it spreads easily and early, and the tumors have a unique biological makeup.

15 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Study sheds new light on key cellular processes involved in Parkinson's disease progression

In a study published in Nature Communications, investigators at Beth Israel Deaconess Medical Center (BIDMC) shed new light on key cellular processes involved in the progression of Parkinson's disease (PD).

15 Nov 2023

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 21, entitled, "Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model."

15 Nov 2023

New study investigates role of rare gene variants in IBD risk for African Americans

The advent of whole genome sequencing technology has prompted an explosion in research into how genetics are associated with disease risk.

15 Nov 2023

Gene News and Research

Latest Gene News and Research

MHRA extends the license of two cystic fibrosis drugs for children aged two to five years old

Avian influenza A H5N1 virus impacts wide range of wildlife in the U.S., study shows

New understanding of lung cancer cells' 'memories' suggests novel treatment approach

Complex genetics behind human cranial vault shape revealed

Experts shed light on how autism affects the diagnosis, treatment of epilepsy and vice versa

New insights into sporadic early-onset Alzheimer's disease

New method unveils the "imageable genome" for medical diagnostics

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

New insights into how cells maintain their identity over generations

Long-term monitoring of gene therapy patients crucial for safety, study says

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Molecular trap offers hope for ALS treatment

AI model predicts patient outcomes across multiple cancer types

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

One in five patients on Nirmatrelvir–Ritonavir experience virologic rebound, new observational study reveals

Researchers discover genetic mechanism behind pancreatic cancer metastasis

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study sheds new light on key cellular processes involved in Parkinson's disease progression

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

New study investigates role of rare gene variants in IBD risk for African Americans

eBook: Using iPSCs models for human disease research and drug discovery eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research