Gene News and Research

Latest Gene News and Research

Researchers identify new potential treatments for children with rare genetic conditions of blood vessels

A research team at the Francis Crick Institute and Great Ormond Street Hospital (GOSH)/UCL Great Ormond Street Institute of Child Health have identified new potential treatments for children with rare genetic conditions of blood vessels, which cause severe, lifelong, and disabling symptoms like seizures and impaired development.

5 Oct 2023

Researchers spearhead a new method to hone in on new cancer drug targets

Searching for new ways to block the growth of cancer cells is like looking for a needle in a haystack. Tumor cells rely on thousands of proteins to function, but only a few of those proteins can be precisely targeted by drugs to treat cancer safely and effectively.

5 Oct 2023

CRISPR gene editing study provides insights into how autism gene affects brain development

Researchers have used CRISPR gene editing, stem cells and human neurons to study the impact of a gene that is commonly mutated in autism.

5 Oct 2023

New computational method improves analysis of single-cell transcriptomic data

Researchers at Memorial Sloan Kettering Cancer Center (MSK) have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data.

5 Oct 2023

New method can help researchers map pancreatic cancer development

Pancreatic cancer is one of the deadliest forms of cancer. This is largely due to the cancer being detected at a late stage. In addition, treatment options for pancreatic cancer are limited.

5 Oct 2023

The metabolic effects of endocrine therapy on diabetes mellitus in breast cancer survivors

Researchers discuss the history of endocrine therapies, highlights their adverse metabolic effects, and emphasizes the need for better biomarkers of diabetes.

5 Oct 2023

Progress and challenges in completing the human gene catalogue

A group of authors reviewed the progress and challenges in annotating the human genome, including protein-coding genes, isoforms, and non-coding RNAs, and advocated for a universal annotation standard for clinical use.

5 Oct 2023

New zebrafish xenograft platform could help screen for glioblastoma treatments

Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study by the Gerhardt and De Smet labs published in EMBO Molecular Medicine.

4 Oct 2023

Cancer tumors hijack genetic program of developing nerves, study shows

Cancer tumors "hijack" the genetic program used by developing nerves. This is shown in a study by researchers at Umeå University, Sweden.

4 Oct 2023

USC receives $2 million grant to advance cell and gene therapy research

The Keck School of Medicine of USC has received $2 million from the California Institute of Regenerative Medicine (CIRM) to further augment its newly launched cGMP Laboratory, a state-of-the-art facility designed to advance early-stage research into clinically viable cell and gene therapies.

4 Oct 2023

Wood cookstove use linked to gastric cancer risk

Researchers conducted a population-based study with a case–control design in rural areas of Honduras in Central America to examine whether wood cookstove use by indigenous populations was associated with increased risk of stomach cancers, including gastric adenocarcinoma.

4 Oct 2023

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Researchers investigated endotype-phenotype associations in atopic dermatitis (AD) beyond its general clinical severity.

4 Oct 2023

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Researchers developed the ATRIVIEW® platform to screen for molecules that promote differentiation neural stem cells (NSCs).

4 Oct 2023

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

The connection between the CHD gene and autism-related gastrointestinal (GI) manifestations.

4 Oct 2023

Could infants' robust immune responses reshape future vaccination strategies?

Utilizing next-gen sequencing techniques, researchers analyzed infants' immune responses to infections, uncovering a predominant innate immune activation unlike adults and older children. This insight could steer child vaccination research and pediatric infection management strategies, potentially revolutionizing infant healthcare.

3 Oct 2023

Gene variants linked to higher risk for nodular melanoma identified

Researchers from The University of Queensland and The Alfred hospital in Melbourne have identified gene variants which may contribute to people being at higher risk for nodular melanoma.

3 Oct 2023

AI tool PARMESAN predicts drug-gene interactions for genetic disorders

To discover new treatments for genetic disorders, scientists need a thorough knowledge of prior literature to determine the best gene/protein targets and the most promising drugs to test.

3 Oct 2023

Research opens the door for better use of people's own immune system T cells to fight cancer

Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can make the cells more robust, potentially opening the door for better use of people's own immune system T cells to fight cancer.

3 Oct 2023

New compound could offer an alternative to injections for people suffering from eye condition

A new compound developed at the University of Illinois Chicago potentially could offer an alternative to injections for the millions of people who suffer from an eye condition that causes blindness.

3 Oct 2023

NIH grant to fund development of new gene therapy platform for brain diseases

A two-phase NIH grant will fund research into a new CRISPR-based gene therapy platform that will target genetic brain diseases like Angelman syndrome and H1-4 (HIST1H1E) syndrome.

3 Oct 2023

Gene News and Research

Latest Gene News and Research

Researchers identify new potential treatments for children with rare genetic conditions of blood vessels

Researchers spearhead a new method to hone in on new cancer drug targets

CRISPR gene editing study provides insights into how autism gene affects brain development

New computational method improves analysis of single-cell transcriptomic data

New method can help researchers map pancreatic cancer development

The metabolic effects of endocrine therapy on diabetes mellitus in breast cancer survivors

Progress and challenges in completing the human gene catalogue

New zebrafish xenograft platform could help screen for glioblastoma treatments

Cancer tumors hijack genetic program of developing nerves, study shows

USC receives $2 million grant to advance cell and gene therapy research

Wood cookstove use linked to gastric cancer risk

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

Could infants' robust immune responses reshape future vaccination strategies?

Gene variants linked to higher risk for nodular melanoma identified

AI tool PARMESAN predicts drug-gene interactions for genetic disorders

Research opens the door for better use of people's own immune system T cells to fight cancer

New compound could offer an alternative to injections for people suffering from eye condition

NIH grant to fund development of new gene therapy platform for brain diseases

eBook: Using iPSCs models for human disease research and drug discovery eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research