Gene News and Research

Latest Gene News and Research

Mutant gene that starves the brain of serotonin 10 times more prevalent in depressed patients

A mutant gene that starves the brain of serotonin, a mood-regulating chemical messenger, has been discovered and found to be 10 times more prevalent in depressed patients than in control subjects, report researchers funded by the National Institutes of Health’s National Institute of Mental Health (NIMH) and National Heart Lung and Blood Institute (NHLBI).

21 Dec 2004

ChondroGene and Pfizer osteoarthritis collaboration

ChondroGene reported today that it has entered into a new two-year research collaboration with Pfizer for the identification of novel therapeutic targets and biomarkers for the treatment and diagnosis of osteoarthritis (OA).

21 Dec 2004

Major step forward in using saliva to detect oral cancer

Scientists funded by the National Institute of Dental and Craniofacial Research reported taking a major step forward in using saliva to detect oral cancer.

21 Dec 2004

Cancer drug paclitaxel may reduce the adverse effects of Alzheimer's disease

In a preclinical efficacy trial, the cancer drug paclitaxel (Paxceed)–which exerts its effects by binding to and stabilizing microtubules inside cells–reduced the adverse effects of Alzheimer's disease (AD)-like pathology in a mouse model.

20 Dec 2004

Blocking gene's activity may control deadly skin cancer without harming normal cells

Researchers at Dana-Farber Cancer Institute and Children's Hospital Boston have discovered that malignant melanoma, the potentially lethal skin cancer, can't grow without a steady supply of a protein that normal cells can do without.

20 Dec 2004

Blocking a key molecule protects breast implants, permanent catheters, pacemakers and artificial joints from rejection and damage by the body

Blocking a key molecule protects breast implants, permanent catheters, pacemakers, artificial joints, glucose sensors for diabetics, and other biomaterials from rejection and damage by the body, according to a study published this month in The American Journal of Pathology.

20 Dec 2004

DLX5 gene may play a role in the pathology of Rett Syndrome

A research team led by Terumi Kohwi-Shigematsu of the Life Sciences Division of Lawrence Berkeley National Laboratory has identified a gene, DLX5, that may play a role in the pathology of Rett Syndrome, a devastating neurological disorder diagnosed almost exclusively in girls.

20 Dec 2004

Messenger RNA not only are measurable in saliva but can indicate a developing tumor

Scientists funded by the National Institute of Dental and Craniofacial Research reported today taking a major step forward in using saliva to detect oral cancer.

20 Dec 2004

Gene expression analysis software

Case Western Reserve University has announced that its BAMarray™ software is now available for download and licensing. The statistical software analyzes gene expression data -- one of the hottest areas of biology research.

20 Dec 2004

Gene therapy effective in helping children with severe combined immunodeficiency (SCID)

A UK study in this week’s issue of THE LANCET provides further evidence that gene therapy can be effective in creating a functional immune system for infants with severe combined immunodeficiency (SCID).

20 Dec 2004

Permanent resistance to antibiotics cannot be prevented

Dutch research has shown that the development of permanent resistance by bacteria and fungi against antibiotics cannot be prevented in the longer-term. The only solution is to reduce the dependence on antibiotics by using these less.

20 Dec 2004

Rett Syndrome, the first identified epigenetic disease - linked to specific defects in the three-dimensional folding of chromatin

Sometime between the age of 6 and 18 months, after a period of seemingly normal development, girls affected with Rett Syndrome lose interest in play; they gradually become withdrawn and anxious, develop autistic-like behaviors, and acquire specific symptoms like repetitive teeth-grinding and hand-wringing.

20 Dec 2004

New theory driving evolutionary changes

Researchers at UT Southwestern Medical Center at Dallas have used canine DNA to identify a genetic mutation mechanism they believe is responsible for rapid evolutionary changes in the physical appearance of many species.

14 Dec 2004

New cancer detection technology from Rubicon Genomics

Rubicon Genomics has invented a more effective technology for the diagnosis and prognosis of cancer compared to what hospitals and reference laboratories use today. MethylPlex™ is the most sensitive method in use to detect the patterns of abnormal DNA methylation arising in the serum and urine of patients during tumor formation and progression.

14 Dec 2004

Instead of chemotherapy, drugs that influence the X protein's behavior might become an alternative cancer therapy

Identifying the link between chronic hepatitis B infection and liver cancer may one day help cancer patients sidestep the poison of chemotherapy, a Purdue University study suggests.

13 Dec 2004

Start today of human tests for a preventive vaccine against the respiratory disease SARS

Powerful research tools that speed up vaccine development have led to the start today of human tests for a preventive vaccine against the respiratory disease SARS. The disease killed hundreds of people around the world before it was brought under control in 2003 with aggressive conventional public health measures.

13 Dec 2004

Celebrex like gene suppresses the growth of colon cancer

Cancer researchers at the Case Western Reserve University (Case) School of Medicine, University Hospitals of Cleveland (UHC) and the Howard Hughes Medical Institute have found a "Celebrex-like" gene that suppresses the growth of colon cancer.

13 Dec 2004

Wiping out a protein in skin cancer cells could significantly stall melanoma tumor development

The protein, Akt3, appears to be responsible for promoting tumor cell survival and development in 43 percent to 60 percent of non-inherited melanomas.

13 Dec 2004

New approach to genomic testing identifies women with low risk of breast cancer recurrence

An initial validation study presented by Exagen Diagnostics at the San Antonio Breast Cancer Symposium suggests it may soon be possible to distinguish good prognosis from poor prognosis in any newly diagnosed breast cancer patient based on DNA changes in the patient's tumor.

13 Dec 2004

Patent issued for generating genetically evolved mammalian cells through the regulation of mismatch repair

Morphotek announced today the issuance of United States Patent 6,825,038 covering the regulation of mismatch repair (MMR), a powerful process for generating functional diversity in mammalian cells, to yield sibs exhibiting desirable phenotypes for target discovery, drug screening and/or product development.

13 Dec 2004

Gene News and Research

Latest Gene News and Research

Mutant gene that starves the brain of serotonin 10 times more prevalent in depressed patients

ChondroGene and Pfizer osteoarthritis collaboration

Major step forward in using saliva to detect oral cancer

Cancer drug paclitaxel may reduce the adverse effects of Alzheimer's disease

Blocking gene's activity may control deadly skin cancer without harming normal cells

Blocking a key molecule protects breast implants, permanent catheters, pacemakers and artificial joints from rejection and damage by the body

DLX5 gene may play a role in the pathology of Rett Syndrome

Messenger RNA not only are measurable in saliva but can indicate a developing tumor

Gene expression analysis software

Gene therapy effective in helping children with severe combined immunodeficiency (SCID)

Permanent resistance to antibiotics cannot be prevented

Rett Syndrome, the first identified epigenetic disease - linked to specific defects in the three-dimensional folding of chromatin

New theory driving evolutionary changes

New cancer detection technology from Rubicon Genomics

Instead of chemotherapy, drugs that influence the X protein's behavior might become an alternative cancer therapy

Start today of human tests for a preventive vaccine against the respiratory disease SARS

Celebrex like gene suppresses the growth of colon cancer

Wiping out a protein in skin cancer cells could significantly stall melanoma tumor development

New approach to genomic testing identifies women with low risk of breast cancer recurrence

Patent issued for generating genetically evolved mammalian cells through the regulation of mismatch repair

eBook: Using iPSCs models for human disease research and drug discovery eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation