Gene News and Research

Latest Gene News and Research

Hmga1 protein could be an important therapeutic target for osteoporosis

New research published in The FASEB Journal indicates that increasing the expression of a particular gene may help to prevent bone loss associated with postmenopausal osteoporosis.

9 Aug 2023

Mice lacking TMCO3 gene have shortened bones

Through next-generation sequencing, investigators have identified a mutation in the TMCO3 gene in two sisters with short stature.

9 Aug 2023

New treatment approach shows promise in reversing hormone resistance in breast cancer

A collaborative study between LSU Health New Orleans School of Medicine, the University of Rochester and Cellestia Biotech AG, a biopharmaceutical company headquartered in Basel, Switzerland, provides compelling evidence that combining an investigational oral drug with standard-of-care medications reverts hormone resistance and increases Rx effectiveness in experimental models of estrogen-receptor positive (ER+) and triple-negative breast cancers (TNBC), respectively.

9 Aug 2023

Study reveals the genetics of hair whorl direction

The first gene mapping study on human scalp hair whorls not only shows that hair whorl direction has a genetic basis, but also that it is affected by multiple genes.

9 Aug 2023

ADHD diagnosis in childhood vs adulthood: is there a difference in genetic architecture?

Researchers investigated whether individuals diagnosed with ADHD during childhood vs adulthood differed in terms of unique and shared genetic and functional architectures.

9 Aug 2023

Effect of mutations in cancer-driving genes across human cancers

Effect of mutations in cancer-driving genes across human cancers.

9 Aug 2023

The impact of epigenetic features on breast cancer treatment and outcomes

The impact of epigenetic features on breast cancer treatment and outcomes.

9 Aug 2023

Nanotechnology's triple threat: Advancing precision cancer treatment

The design of tumor tissue-, cell-, and organelle-targeted cancer nanomedicines.

9 Aug 2023

High-level BPA exposure may affect male fertility

Scientists discuss the effect of bisphenol A on human male fertility.

9 Aug 2023

Lyme disease bacteria adapt to animal hosts at the variant level, study finds

A study looks at the mechanisms behind genetic variation in the bacteria that cause Lyme disease. Lyme disease is the most common vector-transmitted disease in the United States, with around 476,000 human cases annually.

8 Aug 2023

NLRP3 inflammasome plays a role in podocyte aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span."

8 Aug 2023

Nationwide Children's Hospital pioneers new gene therapy for Duchenne muscular dystrophy

In a landmark moment for the Abigail Wexner Research Institute at Nationwide Children's, a 5-year-old from Bellefontaine, Ohio, received the first dose of a recently approved gene therapy for Duchenne muscular dystrophy at Nationwide Children's Hospital, where the therapy was invented and initially tested.

8 Aug 2023

Identification of plasma proteins associated with ovarian cancer risk

Researchers performed proteomic Mendelian randomization as well as co-localization analyses to identify drug targets for ovarian cancer.

8 Aug 2023

Study finds genetic overlap between IBS, gastrointestinal diseases, and psychiatric disorders

Researchers characterized the genetic architecture of IBS and investigated genetic overlap with gastrointestinal and psychiatric phenotypes.

8 Aug 2023

Molecular insights: Detecting gene fusions offers new avenues for advanced cancer management

Study identifies gene fusions to understand their relationship with observed pathologies in cancer patients.

8 Aug 2023

The green tea effect: From gut microbes to weight loss, new insights emerge

The impact of green tea and its functional components on body weight and gut microbiota regulation.

8 Aug 2023

AI-based predictive tool could help guide treatment of cancer

Researchers at Dana-Farber Cancer Institute have created an AI-based tool that uses tumor gene sequencing data to predict the primary source of a patient's cancer.

7 Aug 2023

Researchers develop new method to find mutations in pediatric brain tumors

Researchers at Uppsala university have developed a new method to find mutations in brain tumors in children.

7 Aug 2023

Metrion Biosciences announces launch of Good Laboratory Practice (GLP) hERG Screening Service

Metrion Biosciences Limited, the specialist ion channel contract research and drug discovery company, today announced it has received notification from the UK’s Medicines and Healthcare Products Regulatory Agency (MHRA) that the Company is now a member of the UK GLP (Good Laboratory Practice) Compliance Monitoring Programme, and is, therefore, able to offer GLP compliant hERG ion channel screening services to the global life sciences community.

From Metrion Biosciences Limited 7 Aug 2023

The genetics of resting heart rate and its connection to cardiovascular disorders

Researchers investigated the genetics behind resting heart rate and its impact on cardiovascular disease.

7 Aug 2023

Gene News and Research

Latest Gene News and Research

Hmga1 protein could be an important therapeutic target for osteoporosis

Mice lacking TMCO3 gene have shortened bones

New treatment approach shows promise in reversing hormone resistance in breast cancer

Study reveals the genetics of hair whorl direction

ADHD diagnosis in childhood vs adulthood: is there a difference in genetic architecture?

Effect of mutations in cancer-driving genes across human cancers

The impact of epigenetic features on breast cancer treatment and outcomes

Nanotechnology's triple threat: Advancing precision cancer treatment

High-level BPA exposure may affect male fertility

Lyme disease bacteria adapt to animal hosts at the variant level, study finds

NLRP3 inflammasome plays a role in podocyte aging

Nationwide Children's Hospital pioneers new gene therapy for Duchenne muscular dystrophy

Identification of plasma proteins associated with ovarian cancer risk

Study finds genetic overlap between IBS, gastrointestinal diseases, and psychiatric disorders

Molecular insights: Detecting gene fusions offers new avenues for advanced cancer management

The green tea effect: From gut microbes to weight loss, new insights emerge

AI-based predictive tool could help guide treatment of cancer

Researchers develop new method to find mutations in pediatric brain tumors

Metrion Biosciences announces launch of Good Laboratory Practice (GLP) hERG Screening Service

The genetics of resting heart rate and its connection to cardiovascular disorders

Industry Focus: Cell & Gene Therapy eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research