Gene News and Research

Latest Gene News and Research

Immune cells targeting core protein play an important role in early immune defense against COVID-19

LMU immunologists have studied the early immune response to acute SARS-CoV-2 infection and show how vaccines could be improved in future.

25 May 2023

Genetic predisposition to lipids, Alzheimer’s and heart disease in MLXIPL gene shaped by exogenous exposures

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Exogenous exposures shape genetic predisposition to lipids, Alzheimer's, and coronary heart disease in the MLXIPL gene locus."

25 May 2023

Study highlights the genetic basis of cognitive biases in decision making

Have you ever made a decision that, in hindsight, seemed irrational? A new study with mice, which could have implications for people, suggests that some decisions are, to a certain extent, beyond their control.

25 May 2023

Manipulating a signaling protein to slow down muscular dystrophy

A team of researchers at the University of Houston College of Pharmacy is reporting that by manipulating TAK1, a signaling protein that plays an important role in development of the immune system, they can slow down disease progression and improve muscle function in Duchenne muscular dystrophy (DMD).

25 May 2023

People with Alzheimer's disease more likely to develop epilepsy and vice versa

People with a genetic predisposition for Alzheimer's disease may have an increased risk of epilepsy and people with a certain type of epilepsy may have an increased risk of developing Alzheimer's disease, according to a study published in the May 24, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

25 May 2023

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

In this behind-the-scenes interview, we speak to Dr. Sinead Knight, chair of SLAS Europe 2023, about this years programme, highlighting the key topics and speakers.

From Society for Laboratory Automation and Screening (SLAS) 25 May 2023

Novel regulators of COPD determined by epigenetic profiling

Impaired function of lung fibroblast is considered causative for symptoms of the incurable lung disease COPD (Chronic Obstructive Pulmonary Disease).

25 May 2023

Combination of genetic and environmental factors increases the risk of cleft lip

A cleft lip or palate arises from the combined effects of genes and inflammatory risk factors experienced during pregnancy, such as smoking or infections, finds a new study led by UCL researchers.

24 May 2023

bit.bio launches new custom disease model cells offering, advancing disease research & drug discovery

Researchers can now order their mutation of choice in bit.bio’s opti-oxTM powered human-iPSC derived cells, receiving consistent, defined, cryopreserved products that can be immediately incorporated into drug discovery workflows.

From bit.bio 24 May 2023

The adaptive immunity of human endemic viruses

Researchers studied the evolution of the ability of viruses to evade the neutralizing antibodies.

24 May 2023

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Gut dysfunction and the presence of lipopolysaccharide (LPS) endotoxins contribute to the pathogenesis of Parkinson's disease (PD), leading to neuroinflammation and neurodegeneration. Modulating the gut microbiome and reducing LPS levels may hold potential as treatment strategies for PD.

24 May 2023

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

A new study shows that total RPE65 protein levels in mice with autosomal dominant retinitis pigmentosa were doubled following subretinal delivery of adeno-associated virus (AAV)-RPE65 gene supplementation.

23 May 2023

$11.6 million NIDA grant supports the study of cannabis effects on HIV-infected brains

Weill Cornell Medicine has been awarded a five-year, $11.6 million grant from the National Institute on Drug Abuse of the National Institutes of Health to study the effects cannabis, including marijuana and compounds derived from it, may have on the brains of those living with HIV.

23 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

High HDL-C levels and cardiovascular risks - what you need to know!

Research paper investigates the relationship between very high levels of high-density lipoprotein cholesterol (HDL-C) and cardiovascular outcomes in the general population. The study reveals that while men with high HDL-C face an increased risk of all-cause death and cardiovascular death, this association is not observed in women without coronary artery disease.

22 May 2023

Cytoelectric Coupling hypothesis: Fluctuating electric fields shape the brain’s molecular infrastructure

To produce its many functions, including thought, the brain works at many scales. Information such as goals or images is represented by coordinated electrical activity among networks of neurons, while within and around each neuron a mix of proteins and other chemicals physically carries out the mechanics of participating in the network.

22 May 2023

Gene News and Research

Latest Gene News and Research

Immune cells targeting core protein play an important role in early immune defense against COVID-19

Genetic predisposition to lipids, Alzheimer’s and heart disease in MLXIPL gene shaped by exogenous exposures

Study highlights the genetic basis of cognitive biases in decision making

Manipulating a signaling protein to slow down muscular dystrophy

People with Alzheimer's disease more likely to develop epilepsy and vice versa

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

Novel regulators of COPD determined by epigenetic profiling

Combination of genetic and environmental factors increases the risk of cleft lip

bit.bio launches new custom disease model cells offering, advancing disease research & drug discovery

The adaptive immunity of human endemic viruses

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Looking at cancer drugs to help put the brakes on classic indicators of aging

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

$11.6 million NIDA grant supports the study of cannabis effects on HIV-infected brains

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

High HDL-C levels and cardiovascular risks - what you need to know!

Cytoelectric Coupling hypothesis: Fluctuating electric fields shape the brain’s molecular infrastructure

Newly developed method can help identify the special differences in genetic information

Surviving without glucose: uridine-derived ribose as an alternative energy source

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research