Gene News and Research

Latest Gene News and Research

A system for detecting emerging SARS-CoV-2 variants

An article published in the journal Nature Medicine examines the unpredictable evolution of the ongoing COVID-19 pandemic.

2 Jun 2022

Brain motor and fear circuits orchestrate the immune response to acute stress

A new study explores how acute stressors affected mice in terms of their immune responses in specific regions of the brain.

2 Jun 2022

A non-coding RNA molecule regulates mitochondrial gene expression in human cells, study shows

A new study published in the journal Cell shows that a non-coding RNA molecule regulates mitochondrial gene expression in human cells.

2 Jun 2022

Cellular changes in astrocytes play a crucial role in regulating outcomes for CNS disorders

Investigators at Cedars-Sinai have comprehensively mapped molecular activity in the brain and spinal cord that is responsible for regulating the body's response to central nervous system (CNS) disorders such as Alzheimer's, Huntington's disease and spinal cord injuries.

2 Jun 2022

New study in mice shows alternate origins of plaques in Alzheimer’s disease

A breakdown in how brain cells rid themselves of waste precedes the buildup of debris-filled plaques known to occur in Alzheimer's disease, a new study in mice shows.

2 Jun 2022

NIH sponsors the trial of monoclonal antibody to prevent asthma exacerbations in urban youth

The National Institutes of Health has launched a clinical trial testing whether a monoclonal antibody, dupilumab, can reduce asthma attacks and improve lung function and asthma symptoms in children with poorly controlled allergic asthma who live in low-income urban neighborhoods.

2 Jun 2022

New findings by HBP researchers provide a better understanding of human brain organization

Specific cellular, molecular and gene expression patterns in brain areas are linked to function, but their precise relationships remain largely unknown.

2 Jun 2022

Phylogenomic characterization of the first genome sequences of the monkeypox virus outbreak variant

Researchers characterized infections caused by the monkeypox virus (MPXV).

2 Jun 2022

The effects of accessory protein mutations and other non-spike mutations on SARS-CoV-2 pathogenesis

Researchers looked into the role played by the accessory proteins using synthetic genomics assembly technology

2 Jun 2022

New discovery could lead to highly effective ways to treat influenza

It happens every year, especially in winter. A virus saunters into your wide-open respiratory tract, worms its way into lung cells, and, next thing you know, you're lying in bed with a fever, aches, and chills - classic symptoms of influenza, or flu.

1 Jun 2022

Stem cell model could provide insights into biological mechanisms that underlie neuropsychiatric disorders

Researchers from the Icahn School of Medicine at Mount Sinai have applied a novel stem cell model to map disease risk variants in human neurons, which could help provide insights into the biological mechanisms that underlie neuropsychiatric disorders such as autism and schizophrenia.

1 Jun 2022

New study uncovers the impact of genetic mutations on lifelong blood cell production

New research has uncovered how genetic mutations hijack the production of blood cells in different periods of life.

1 Jun 2022

Microgravity culture during spaceflight enhances microbial infection process in 3D intestinal models

Infectious microbes have evolved sophisticated means to invade host cells, outwit the body's defenses and cause disease.

1 Jun 2022

New research may open a window to treating aggressive form of B-cell acute lymphoblastic leukemia

Survival has improved greatly in children with acute lymphocytic leukemia (ALL). But a certain form of ALL that occurs mostly in babies is still very lethal, with a survival rate below 50 percent: B-cell acute lymphoblastic leukemia with rearrangements of the mixed lineage leukemia gene, or MLL B-ALL.

1 Jun 2022

People with food allergies less likely to become infected with SARS-CoV-2, study finds

A National Institutes of Health-funded study has found that people with food allergies are less likely to become infected with SARS-CoV-2, the virus that causes COVID-19, than people without them. In addition, while previous research identified obesity as a risk factor for severe COVID-19, the new study has identified obesity and high body mass index (BMI) as associated with increased risk for SARS-CoV-2 infection.

1 Jun 2022

Gene therapy for degenerative retinal disease has no safety concerns but fails to improve vision loss

A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, with even the highest dose. LHON affects the optic nerve, which carries visual signals from the light-sensing retina to the brain.

1 Jun 2022

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

Researchers identified a single viral gene product, the accessory factor ORF7a, facilitating SARS-CoV-2 immune evasion by downregulating the surface expression of MHC class I molecules.

1 Jun 2022

UCI-led study identifies sex-specific circuits of muscle signaling to other tissues

A new University of California, Irvine-led study identifies sex-specific circuits of muscle signaling to other tissues and that the organs and processes muscle impacts are markedly different between males and females.

31 May 2022

Researchers identify molecular characteristics linked to increased likelihood of post-vaccination fatigue

Despite their strong effectiveness against SARS-CoV-2, mRNA-based COVID-19 vaccines are associated with adverse post-vaccination effects, such as fatigue; how can this be avoided? In a new study publishing May 31st in the open-access journal PLOS Biology, Ayesa Syenina of the Duke–NUS Medical School in Singapore and colleagues report that a new analysis of blood samples from people vaccinated for COVID-19 has identified distinct molecular characteristics linked to an increased likelihood of post-vaccination fatigue.

31 May 2022

Aging does not influence liver renewal, research shows

The liver has a unique ability to regenerate after damage. However, it was unknown whether this ability decreases as we age.

31 May 2022

Gene News and Research

Latest Gene News and Research

A system for detecting emerging SARS-CoV-2 variants

Brain motor and fear circuits orchestrate the immune response to acute stress

A non-coding RNA molecule regulates mitochondrial gene expression in human cells, study shows

Cellular changes in astrocytes play a crucial role in regulating outcomes for CNS disorders

New study in mice shows alternate origins of plaques in Alzheimer’s disease

NIH sponsors the trial of monoclonal antibody to prevent asthma exacerbations in urban youth

New findings by HBP researchers provide a better understanding of human brain organization

Phylogenomic characterization of the first genome sequences of the monkeypox virus outbreak variant

The effects of accessory protein mutations and other non-spike mutations on SARS-CoV-2 pathogenesis

New discovery could lead to highly effective ways to treat influenza

Stem cell model could provide insights into biological mechanisms that underlie neuropsychiatric disorders

New study uncovers the impact of genetic mutations on lifelong blood cell production

Microgravity culture during spaceflight enhances microbial infection process in 3D intestinal models

New research may open a window to treating aggressive form of B-cell acute lymphoblastic leukemia

People with food allergies less likely to become infected with SARS-CoV-2, study finds

Gene therapy for degenerative retinal disease has no safety concerns but fails to improve vision loss

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

UCI-led study identifies sex-specific circuits of muscle signaling to other tissues

Researchers identify molecular characteristics linked to increased likelihood of post-vaccination fatigue

Aging does not influence liver renewal, research shows

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging