Gene News and Research

Latest Gene News and Research

Oxidation-antioxidant imbalance in the blood may be an early indicator of Alzheimer's disease

Research conducted by the Ph.D student Mohamed Raâfet Ben Khedher and the postdoctoral researcher Mohamed Haddad of the Institut national de la recherche scientifique has shown that an oxidation-antioxidant imbalance in the blood is an early indicator of Alzheimer's disease, rather than a consequence.

12 Oct 2021

Research reveals components of Sinbis virus ribonucleoproteins

To address this gap in research regarding the understanding of post-replicative alphavirus RNPs, scientists have created a novel proteome-wide approach known as viral RNA interactome capture (vRIC). This study is available in the bioRxiv* preprint server while awaiting peer review.

11 Oct 2021

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

Recently, scientists have developed a bacterial two-hybrid (B2H) system to study the PPIs of SARS-CoV-2 in a heterologous non-eukaryotic system. This study is available on the bioRxiv* preprint server. Put simply, the B2H system could be used to analyze the SARS-CoV-2 proteome.

11 Oct 2021

CRISPR/Cas9-directed epigenetic editing reveals diverse transcriptomic regulation and functional effects

Oncotarget published "Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing" which reported that the adequate functioning of this process is indispensable for tissue homeostasis and cell fate determination.

11 Oct 2021

Newly discovered molecule could be used to prevent collateral harm to vital organs during surgery

A newly detected molecule that helps reduce damage from sustained loss of blood flow to cells and tissues could eventually be used to prevent collateral harm to vital organs during surgery, according to University of Utah Health scientists.

11 Oct 2021

Drug developed at Duke is approved by FDA as only therapy for congenital athymia

The phone rang into the pediatric unit that Louise Markert, M.D., Ph.D., was staffing as a junior faculty member in 1991. Had she not answered, there would have been little hope for the more than one hundred patients who were subsequently treated.

11 Oct 2021

Penn Medicine's new Pavilion is set to open this month to staff, patients, and visitors

Referred to as a "Beacon of Hope," Penn Medicine's new Pavilion, one of the largest hospital projects underway in the United States, opens to staff, patients, and visitors this month.

11 Oct 2021

Common oral diuretic pill may be a potential candidate for Alzheimer's treatment

A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer's disease treatment for those who are at genetic risk, according to findings published in Nature Aging.

11 Oct 2021

New algorithm provides a high-definition analysis of genome organization in single cells

Within the microscopic boundaries of a single human cell, the intricate folds and arrangements of protein and DNA bundles dictate a person's fate: which genes are expressed, which are suppressed, and - importantly - whether they stay healthy or develop disease.

11 Oct 2021

Plasmonic sensing of isothermally amplified nucleic acids and single-molecule detection of SARS-CoV-2

A new study finds that plasmonic sensing of LAMP amplicons through DNA hybridization enables highly specific detection of SARS-CoV-2 RNA.

11 Oct 2021

CDC and ClinGen partner to develop expert curated variant list for the genomic community

The Centers for Disease Control and Prevention's Genetic Testing Reference Material Program (GeT-RM) has partnered with the Clinical Genome Resource (ClinGen) to develop a publicly available list of 546 expert curated pathogenic variants in 84 genes for use in next-generation sequencing (NGS) genetic testing.

11 Oct 2021

Exosomal and non-exosomal miRNAs may serve as biomarkers for HCV-related cirrhosis, liver cancer

Oncotarget published "Exosomal and non-exosomal miRNA expression levels in patients with HCV-related cirrhosis and liver cancer" which reported that patients with HCV-related cirrhosis are at risk for liver cancer development.

11 Oct 2021

New metagenome assembler can generate accurate DNA sequences

Metagenomics often involves sequencing DNA samples that can only be described as "tricky." Such DNA shows high heterogeneity, which can cause interspecies misassemblies.

11 Oct 2021

NIH awards more than $8 million to support seven high-risk, high-reward projects at Penn Medicine

The National Institutes of Health has awarded grants to researchers in the Perelman School of Medicine at the University of Pennsylvania to support "highly innovative and broadly impactful" biomedical science through the NIH Common Fund's High-Risk, High-Reward Research program. The seven awards total approximately $8.2 million over five years,

8 Oct 2021

Genetics can influence a person's response to Alzheimer's disease pathology, research suggests

A recently released paper from the Department of Physiology and Sanders-Brown Center on Aging (SBCoA) at the University of Kentucky College of Medicine suggests that your genetics can influence your response to Alzheimer's disease pathology.

8 Oct 2021

Characterization of circulating neutrophils from hospitalized COVID-19 patients

A new preprint deals with the characterization of neutrophil phenotypes in an attempt to provide biomarkers that can predict severe disease in patients hospitalized with COVID-19.

8 Oct 2021

Study supports efficacy and safety of lung-selective nanotherapy against SARS-CoV-2 infection

A new preprint shows the potential role of a host protease cathepsin L inhibitor, which mediates viral entry into the host cell by its effect on the viral spike protein.

8 Oct 2021

mRNA vaccination associated with decreased risk of COVID-19 infection and hospitalization in U.S. veterans

Researchers from the U.S. Veterans Affairs have examined the U.S. effort to vaccinate its Veteran population to investigate further.

8 Oct 2021

Adapting biological research and development to COVID-19

In this interview, News-Medical talks to Dr Yuning Chen, about the work he does with Sino Biological and how they have adapted their research & development to the COVID-19 pandemic.

From Sino Biological Inc. 8 Oct 2021

Chilblain-like lesions and COVID-19

The ongoing COVID-19 pandemic brought about by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has also been responsible for various cutaneous manifestations. Among them, chilblain-like lesions (CLL) have been found to occur more frequently.

7 Oct 2021

Gene News and Research

Latest Gene News and Research

Oxidation-antioxidant imbalance in the blood may be an early indicator of Alzheimer's disease

Research reveals components of Sinbis virus ribonucleoproteins

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

CRISPR/Cas9-directed epigenetic editing reveals diverse transcriptomic regulation and functional effects

Newly discovered molecule could be used to prevent collateral harm to vital organs during surgery

Drug developed at Duke is approved by FDA as only therapy for congenital athymia

Penn Medicine's new Pavilion is set to open this month to staff, patients, and visitors

Common oral diuretic pill may be a potential candidate for Alzheimer's treatment

New algorithm provides a high-definition analysis of genome organization in single cells

Plasmonic sensing of isothermally amplified nucleic acids and single-molecule detection of SARS-CoV-2

CDC and ClinGen partner to develop expert curated variant list for the genomic community

Exosomal and non-exosomal miRNAs may serve as biomarkers for HCV-related cirrhosis, liver cancer

New metagenome assembler can generate accurate DNA sequences

NIH awards more than $8 million to support seven high-risk, high-reward projects at Penn Medicine

Genetics can influence a person's response to Alzheimer's disease pathology, research suggests

Characterization of circulating neutrophils from hospitalized COVID-19 patients

Study supports efficacy and safety of lung-selective nanotherapy against SARS-CoV-2 infection

mRNA vaccination associated with decreased risk of COVID-19 infection and hospitalization in U.S. veterans

Adapting biological research and development to COVID-19

Chilblain-like lesions and COVID-19

Genomics - Industry Focus eBook (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research