Gene News and Research

Latest Gene News and Research

UVA researchers discover potential treatment approaches for muscle loss in myotonic dystrophy type 1

University of Virginia School of Medicine researchers have identified new insights and potential treatment approaches for muscle loss in myotonic dystrophy type 1 (DM1), the most common form of muscular dystrophy.

7 Jun 2021

Researchers create cellular and spatial “atlas” of the choroid plexus during different life stages

Once viewed merely as a producer of the cerebrospinal fluid (CSF) bathing the brain and spinal cord, the choroid plexus is now known to be a key player in brain development and immunity.

7 Jun 2021

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

Researchers recently reviewed current knowledge on links between autophagy and coronaviruses and how this knowledge can be used to repurpose autophagy modulators as potential treatment options for COVID-19. The review is published in the journal Frontiers in Microbiology.

7 Jun 2021

New drug reduces tumor size in lung cancer patients who have a specific, disease-causing change

A new drug reduced tumor size in patients who have lung cancer with a specific, disease-causing change in the gene KRAS, a study found.

7 Jun 2021

International travelers often return home with new bacterial strains, confirms study

Carried like stowaways in the guts of international travelers, new and potentially deadly strains of antimicrobial resistant superbugs may be coming to a community near you, suggests new research from Washington University School of Medicine in St. Louis.

7 Jun 2021

Study finds molecular pathway that can explain how chronic kidney disease induces heart failure

According to the Global Burden of Disease Study 2017, close to nine percent of the global population lives with some form of chronic kidney disease, or CKD. Not only does the condition affect renal function, CKD has long been associated with increased risk of cardiovascular disease.

5 Jun 2021

Gene offers some level of protection from severe Covid

The first evidence of a genetic link explaining why some people who catch Covid-19 don't become sick has been discovered.

5 Jun 2021

How mass screening efforts have helped identify more cases of celiac disease in children

A new mass screening program of school-aged children in Italy found that the overall prevalence of celiac disease has almost doubled in the past 25 years.

4 Jun 2021

A lack of oversight for unproven stem cell interventions is a global public health problem

Authors are urging the WHO to establish an Exert Advisory Committee on Regenerative Medicine to provide harmony to the national regulations on the SCI industry.

4 Jun 2021

Research reveals paternal transmission of stress responses to offspring via sperm

Male mice more susceptible to stress can pass down their behaviors to offspring via changes in their sperm’s genetic code, according to new research published in JNeurosci.

4 Jun 2021

Study brings to light the role of a cellular protein in COVID-19 infections

Angiotensin-converting enzyme 2 (ACE2), a protein found on the surface of lung cells, facilitates the entry of the novel coronavirus into host cells.

4 Jun 2021

Study identifies new genetic variants that cause developmental disorders in children

Non-coding regions of DNA could hold the key to diagnosing developmental disorders in children, new research suggests.

4 Jun 2021

African cichlid fish could serve as a premier model of social disorders

Beau Alward, University of Houston assistant professor of psychology, who holds a joint appointment in biology and biochemistry and is director of the Social Neuroscience Lab, has received the Beckman Young Investigator Award by the Arnold and Mabel Beckman Foundation.

4 Jun 2021

Mast cell activation may underlie inflammation in severe COVID-19

A new preprint research paper posted to the medRxiv* server points to mast cells as major culprits in the etiology of severe and critical COVID-19. This could suggest suitable therapeutic and preventive interventions to reduce the morbidity and mortality of this viral illness.

3 Jun 2021

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Type 2 diabetes patients who are not overweight and who have had the disorder for less than a decade can benefit from stromal stem cells transplanted from their own bone marrow, according to a study published today in STEM CELLS Translational Medicine.

3 Jun 2021

Cdkn1a transcript variant 2 is selectively elevated during natural aging across mouse tissues

Aging published "Cdkn1a transcript variant 2 is a marker of aging and cellular senescence" which reported that cellular senescence is a cell fate response characterized by a permanent cell cycle arrest driven primarily the by cell cycle inhibitor and tumor suppressor proteins p16Ink4a and p21Cip1/Waf1.

3 Jun 2021

Study: Lung squamous patients harboring druggable mutations have lower median overall survival

Oncotarget published "Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations" which reported that unlike lung adenocarcinoma patients, there is no FDA-approved targeted-therapy likely to benefit lung squamous cell carcinoma patients.

3 Jun 2021

E6-specific inhibitors offer a unique, strategic approach for treating HPV-HNSCC

Oncotarget published "A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV+ head and neck squamous cell carcinomas" which reported that the incidence of human papillomavirus-positive head and neck squamous cell carcinoma has increased dramatically over the past decades due to an increase in infection of the oral mucosa by HPV.

3 Jun 2021

Epigenetic regulation affects the 3D structure of genome

All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell "reads" different chapters of the genome, thus producing alternative sets of proteins and embarking on different paths.

3 Jun 2021

Scientists develop new gene drive with a built-in genetic barrier

CRISPR-based technologies offer enormous potential to benefit human health and safety, from disease eradication to fortified food supplies. As one example, CRISPR-based gene drives, which are engineered to spread specific traits through targeted populations, are being developed to stop the transmission of devastating diseases such as malaria and dengue fever.

3 Jun 2021

Gene News and Research

Latest Gene News and Research

UVA researchers discover potential treatment approaches for muscle loss in myotonic dystrophy type 1

Researchers create cellular and spatial “atlas” of the choroid plexus during different life stages

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

New drug reduces tumor size in lung cancer patients who have a specific, disease-causing change

International travelers often return home with new bacterial strains, confirms study

Study finds molecular pathway that can explain how chronic kidney disease induces heart failure

Gene offers some level of protection from severe Covid

How mass screening efforts have helped identify more cases of celiac disease in children

A lack of oversight for unproven stem cell interventions is a global public health problem

Research reveals paternal transmission of stress responses to offspring via sperm

Study brings to light the role of a cellular protein in COVID-19 infections

Study identifies new genetic variants that cause developmental disorders in children

African cichlid fish could serve as a premier model of social disorders

Mast cell activation may underlie inflammation in severe COVID-19

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Cdkn1a transcript variant 2 is selectively elevated during natural aging across mouse tissues

Study: Lung squamous patients harboring druggable mutations have lower median overall survival

E6-specific inhibitors offer a unique, strategic approach for treating HPV-HNSCC

Epigenetic regulation affects the 3D structure of genome

Scientists develop new gene drive with a built-in genetic barrier

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging