Gene News and Research

Latest Gene News and Research

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule.

3 Apr 2021

Study uncovers novel mechanism in rare mutation associated with Alzheimer's

A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer's disease in a new study by investigators at the University of Chicago.

3 Apr 2021

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study for neuroblastoma and melanoma.

3 Apr 2021

Research offers new clues about the underlying mechanisms of itch

Eczema, or atopic dermatitis (AD), is sometimes called "the itch that rashes." Often, the itch begins before the rash appears, and, in many cases, the itchiness of the skin condition never really goes away.

3 Apr 2021

Researchers offer large-scale screening of potential broad-spectrum SARS-CoV-2 antivirals

A new study describes the identification of new compounds from a library, with inhibitory activity against several coronaviruses. This study shows the utility of this method, besides identifying compounds that not only inhibit viral shedding in SARS-CoV-2 cultures, but have an immunomodulatory effect that may be useful in mitigating the damaging cytokine storm typical of severe or critical COVID-19.

2 Apr 2021

Comparative study of SARS, MERS, BAT‐SARS, and SARS-CoV-2

Even though a comparative study on the genomic sequences of SARS-CoV, MERS-CoV, and SARS-CoV-2 is available, there is a gap in the research in regards to the comparison between four types of coronaviruses, namely, SARS-CoV, MERS-CoV, BAT-CoV, and SARS-CoV-2. A new study, which deals with the genomic comparison between the sequence of the above-stated four types of coronaviruses, has been published in the Journal of Medical Virology.

2 Apr 2021

Diet and lifestyle may play a significant role in Alzheimer's disease

For years, research to pin down the underlying cause of Alzheimer's Disease has been focused on plaque found to be building up in the brain in AD patients.

2 Apr 2021

Disrupted biochemical pathway can lead to the brain changes characteristic of bipolar disorder

Bipolar disorder affects millions of Americans, causing dramatic swings in mood and, in some people, additional effects such as memory problems.

1 Apr 2021

Single injection of RNA therapy improves vision in patient with genetic form of childhood blindness

A Penn Medicine patient with a genetic form of childhood blindness gained vision, which lasted more than a year, after receiving a single injection of an experimental RNA therapy into the eye.

1 Apr 2021

Researchers identify potential trigger of Crohn's disease

People living with the often-debilitating effects of Crohn's disease may finally gain some relief, thanks to ground-breaking research led by McMaster University.

1 Apr 2021

Fight for Sight funds research to explore gene editing as treatment for inherited retinal diseases

Fight for Sight is funding cutting-edge research at UCL, which will explore whether gene editing could be used to repair faults in genes for some inherited retinal diseases.

1 Apr 2021

Specific gene may play a causal role in heart disease independent of cholesterol levels

High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke.

1 Apr 2021

Study reveals reason behind high risk of leukemia in children with Down syndrome

Children with Down syndrome are 20-times more likely to develop acute lymphocytic leukemia (ALL) and 150-times more likely to develop acute myeloid leukemia (AML) compared to their typical peers.

31 Mar 2021

New portable viral screening test can diagnose COVID-19 in minutes and track variants

Clinicians using a new viral screening test can not only diagnose COVID-19 in a matter of minutes with a portable, pocket-sized machine, but can also simultaneously test for other viruses--like influenza--that might be mistaken for the coronavirus.

31 Mar 2021

Gene therapy restores vison in dogs with severe form of Leber congenital amaurosis

Gustavo Aguirre and William Beltran, veterinary ophthalmologists and vision scientists at the University of Pennsylvania School of Veterinary Medicine, have studied a wide range of different retinal blinding disorders.

31 Mar 2021

Study shows how early life sugar consumption may lead to impaired memory in adulthood

New research shows how drinking sugary beverages early in life may lead to impaired memory in adulthood. The study, published today in Translational Psychiatry, also is the first to show how a specific change to the gut microbiome -- the bacteria and other microorganisms growing in the stomach and intestines -- can alter the function of a particular region of the brain.

31 Mar 2021

Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Streptococcus pyogenes is one of the most important bacterial causes of human skin infections. If S. pyogenes invades deep into the tissue, it can cause life-threatening illnesses, such as sepsis and toxic shock.

31 Mar 2021

Introducing a neuro regenerative gene into mice with spinal cord injury improves motor function

Nagoya University researchers have identified a gene that plays a crucial role in regenerating neurons of African clawed frog tadpoles, which has an unusually high capacity for nerve regeneration.

31 Mar 2021

B.1.1.7 rapidly becoming the dominant SARS-CoV-2 variant in the United States

The faster-spreading B.1.1.7 variant of SARS-CoV-2 first detected in the United Kingdom, the coronavirus that causes COVID-19, is quickly on its way to becoming the dominant variant of the virus in the United States, according to a study from scientists at Scripps Research and the COVID-19 test maker Helix.

31 Mar 2021

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

The ongoing COVID-19 pandemic, caused by SARS-CoV-2, is now established to be more likely to lead to symptomatic and serious illness in males relative to females. This may extend as far back as pregnancy, suggests a recent study.

31 Mar 2021

Gene News and Research

Latest Gene News and Research

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

Study uncovers novel mechanism in rare mutation associated with Alzheimer's

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

Research offers new clues about the underlying mechanisms of itch

Researchers offer large-scale screening of potential broad-spectrum SARS-CoV-2 antivirals

Comparative study of SARS, MERS, BAT‐SARS, and SARS-CoV-2

Diet and lifestyle may play a significant role in Alzheimer's disease

Disrupted biochemical pathway can lead to the brain changes characteristic of bipolar disorder

Single injection of RNA therapy improves vision in patient with genetic form of childhood blindness

Researchers identify potential trigger of Crohn's disease

Fight for Sight funds research to explore gene editing as treatment for inherited retinal diseases

Specific gene may play a causal role in heart disease independent of cholesterol levels

Study reveals reason behind high risk of leukemia in children with Down syndrome

New portable viral screening test can diagnose COVID-19 in minutes and track variants

Gene therapy restores vison in dogs with severe form of Leber congenital amaurosis

Study shows how early life sugar consumption may lead to impaired memory in adulthood

Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Introducing a neuro regenerative gene into mice with spinal cord injury improves motor function

B.1.1.7 rapidly becoming the dominant SARS-CoV-2 variant in the United States

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research