Gene News and Research

Latest Gene News and Research

New model can predict the risk of adverse side effects of cancer treatment

The risk of serious adverse effects on the blood status and bone marrow of patients during chemotherapy can be predicted by a model developed at Linköping University, Sweden.

12 Nov 2020

Peptide-conjugated morpholino oligomers effectively inhibit SARS-CoV-2 in vero cells

The hunt for antivirals has reached an unprecedented pace in light of the coronavirus 2019 (COVID-19) pandemic. The causal agent for this disease – severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – has already infected over 52 million people worldwide, and has subsequently claimed over 1.3 million lives. However, among the innumerable promising drug candidates that help battle the virus and mitigate its damage, none have yet made it to the clinic.

12 Nov 2020

Researchers discover a mechanism that cells use to degrade microRNAs

UT Southwestern researchers have discovered a mechanism that cells use to degrade microRNAs (miRNAs), genetic molecules that regulate the amounts of proteins in cells.

12 Nov 2020

New method using light-activated liposomes is safer, more direct to deliver CRISPR gene therapy

Light-activated liposomes could help to deliver CRISPR gene therapy - and the method could prove safer and more direct than current methods.

12 Nov 2020

TMDU and Fujitsu complete cancer gene network analysis in less than a day

Tokyo Medical and Dental University and Fujitsu Laboratories Limited have recently completed, in less than a day, estimation of the network that represents the influence relationship between genes and prediction of their relationship with infiltration and metastasis based on genes highly likely to be involved in cancer development.

12 Nov 2020

Study explores connection between internal biological clocks and beta cell regeneration

Certain parts of our body, such as the skin or liver, can repair themselves after a damage. Known as cell regeneration, this phenomenon describes how cells that are still functional start to proliferate to compensate for the loss.

12 Nov 2020

$Reduced lead exposure may explain the declining rates of hip fracture$

Reduced lead exposure may explain the declining rates of hip fracture

Hip fractures are one of the leading causes of hospitalization among older adults and are a strong predictor of mortality.

12 Nov 2020

Human coronaviruses cause processing body loss

Researchers continue to expand their knowledge of coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen. Now, a new study published on the preprint server bioRxiv in November 2020 describes a vital mechanism whereby the novel SARS-CoV-2 pathogen can restrict the human host response. In doing so, the study explores how this novel feature of SARS-CoV-2 works and how it results in a reshaping of the human host's immune response.

11 Nov 2020

Research shows a unique T cell receptor repertoire in MIS-C patients

Children with coronavirus disease 2019 (COVID-19) sometimes develop the Multisystem Inflammatory Syndrome in Children (MIS-C), which is associated with high morbidity. The underlying T-cell associated mechanism is described by researchers in a new study published on the preprint server bioRxiv in November 2020, as a response to superantigen activation.

11 Nov 2020

Men and women may require different brain tumor therapy, study finds

The current study shows that the sex differences in the tumor phenotype vary with the effect of the enhancer regulatory molecule bound to Brd4 on the course of stem cell-like differentiation in male and female GBM cells. Inhibition of Brd4 by genetic and pharmacological factors also varies in males and females, both in vivo and in vitro.

11 Nov 2020

Comparison of 240 mammal genomes helps geneticists to identify disease mutations

A large international consortium led by scientists at Uppsala University and the Broad Institute of MIT and Harvard has sequenced the genome of 130 mammals and analyzed the data together with 110 existing genomes to allow scientist to identify which are the important positions in the DNA.

11 Nov 2020

Pitt neuroscientists uncover additional complexities behind sensation of pain from light touch

Researchers from the Pittsburgh Center for Pain Research at the University of Pittsburgh School of Medicine announced today in the journal Neuron that they've uncovered additional complexities behind mechanical allodynia--the sensation of pain from innocuous stimuli, such as light touch.

11 Nov 2020

Discovery of novel hidden gene in SARS-CoV-2

A team of researchers from Germany, Taiwan, and the United States has identified and characterized a new hidden gene in SARS-CoV-2 that is also present in Guangxi pangolin coronaviruses – though, curiously, absent in closely related pangolin and bat coronaviruses.

11 Nov 2020

Researchers uncover potential genetic target for treating endometriosis

Michigan State University researchers have identified a potential genetic target for treating an especially painful and invasive form of endometriosis.

11 Nov 2020

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit neutralizing antibody response in an animal model – even after a single shot with simple jet injection technique.

11 Nov 2020

Host genetic "super-variants" may increase COVID-19 death risk

Researchers at Yale University have identified genetic variants among people of white British ancestry that may increase the risk of dying from coronavirus disease 2019 (COVID-19) – the illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

11 Nov 2020

Study indicates the role of Polβ enzyme in cognitive development

It's a fact of life that things break down. And when they do, whether it's your car, the roof, or a blocked artery, there are people who we can call to help with the repairs.

11 Nov 2020

Gene signature may help develop new therapies against advanced prostate cancer

Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to spread, or metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease.

11 Nov 2020

Study: Optogenetic stimulation of circuit improves symptomatology of Huntington's disease

Huntington's disease is an hereditary neurodegenerative disease featured by alterations in movement, cognitive deficiency and psychiatric disorders resulting from the degeneration of neurons in the striatum nucleus of the brain.

11 Nov 2020

Dietary induction of hepatocyte regeneration may be a viable strategy to enhance gene repair

Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver.

11 Nov 2020

Gene News and Research

Latest Gene News and Research

New model can predict the risk of adverse side effects of cancer treatment

Peptide-conjugated morpholino oligomers effectively inhibit SARS-CoV-2 in vero cells

Researchers discover a mechanism that cells use to degrade microRNAs

New method using light-activated liposomes is safer, more direct to deliver CRISPR gene therapy

TMDU and Fujitsu complete cancer gene network analysis in less than a day

Study explores connection between internal biological clocks and beta cell regeneration

Reduced lead exposure may explain the declining rates of hip fracture

Human coronaviruses cause processing body loss

Research shows a unique T cell receptor repertoire in MIS-C patients

Men and women may require different brain tumor therapy, study finds

Comparison of 240 mammal genomes helps geneticists to identify disease mutations

Pitt neuroscientists uncover additional complexities behind sensation of pain from light touch

Discovery of novel hidden gene in SARS-CoV-2

Researchers uncover potential genetic target for treating endometriosis

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

Host genetic "super-variants" may increase COVID-19 death risk

Study indicates the role of Polβ enzyme in cognitive development

Gene signature may help develop new therapies against advanced prostate cancer

Study: Optogenetic stimulation of circuit improves symptomatology of Huntington's disease

Dietary induction of hepatocyte regeneration may be a viable strategy to enhance gene repair

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