Gene News and Research

Latest Gene News and Research

Pembrolizumab can improve outcomes in patients with metastatic melanoma

A new 10-year analysis led by Igor Puzanov, MD, MSci, FACP, Director of Early Phase Clinical Trials and Chief of Melanoma at Roswell Park Comprehensive Cancer Center and published today in the journal JAMA Oncology provides new insights into an important question.

17 Jul 2020

Game-Changer: A SARS-CoV-2 serological test for 50-cents per sample!

A recent study published in the preprint server medRxiv in July 2020 shows that this is indeed possible. The development of this inexpensive but reliable and sensitive test could change the face of preventive measures for COVID-19 in low-resource settings.

17 Jul 2020

Novel method for selecting the best drug therapy for cancer

Choosing the right drug for each cancer patient is key to successful treatment, but physicians currently have few reliable pointers to guide them in designing treatment protocols.

17 Jul 2020

Researchers unravel key mechanisms behind the mysteries of aging

Molecular biologists and bioengineers at the University of California San Diego have unraveled key mechanisms behind the mysteries of aging. They isolated two distinct paths that cells travel during aging and engineered a new way to genetically program these processes to extend lifespan.

16 Jul 2020

Rare inherited mutation in TP53 gene confers risk of multiple cancers

Rare inherited mutations in the body's master regulator of the DNA repair system – the TP53 gene – can leave people at a higher risk of developing multiple types of cancer over the course of their lives.

16 Jul 2020

Disseminated cancer cells hijack crucial iron micronutrients from native macrophages

In order to survive within the remote and harsh anatomical microenvironments of the central nervous system, the disseminated cancer cells that cause rare yet deadly leptomeningeal metastases (LM) hijack crucial iron micronutrients from native macrophages, researchers report.

16 Jul 2020

Yale researchers uncover potential treatment for lethal Wolfram Syndrome

Yale pharmacology professor Barbara Ehrlich and her team have uncovered a mechanism driving a rare, lethal disease called Wolfram Syndrome and also a potential treatment. Their findings appear in the July 6 edition of Proceedings of the National Academy of Sciences.

16 Jul 2020

GW researcher receives $3.6 million to study HIV-1 resistance to antibody treatments

The National Institutes of Health has awarded $3.6 million to Rebecca Lynch, PhD, assistant professor of microbiology, immunology, and tropical medicine at the George Washington University School of Medicine and Health Sciences, to investigate HIV-1 resistance to antibody treatments.

16 Jul 2020

Study shows how parasitic bacteria cause lesions in the skin and internal organs

Bacteria of the genus Bartonella are parasites that can be transmitted to humans via insect bites and animal scratches, resulting in an infection known as "bartonellosis."

16 Jul 2020

Study could accelerate drug development to reduce age-related diseases

Genes linked to ageing that could help explain why some people age at different rates to others have been identified by scientists.

16 Jul 2020

Researchers solve the mystery of genetic defect in horses

Warmblood fragile foal syndrome is a severe, usually fatal, genetic disease that manifests itself after birth in affected horses.

16 Jul 2020

Study shows how radiotherapy alters the behavior of immune cells in glioblastoma tumors

A Ludwig Cancer Research study has dissected how radiotherapy alters the behavior of immune cells known as macrophages found in glioblastoma (GBM) tumors and shown how these cells might be reprogrammed with an existing drug to suppress the invariable recurrence of the aggressive brain cancer.

16 Jul 2020

Researchers design new model to predict life expectancy of patients with Creutzfeldt‐Jakob disease

Creutzfeldt-Jakob disease (CJD) is a serious minority neurodegenerative disease, with an annual rate of 1.5 cases per million inhabitants, which represents approximately 11 cases each year in Catalonia. CJD is a very rapid and fatal disease, in fact, the mean life expectancy is six months after diagnosis.

15 Jul 2020

Study explains why fetuses and newborns are mostly spared by COVID-19

Amid the coronavirus pandemic, it has been previously suggested that the most vulnerable individuals to developing severe coronavirus disease (COVID-19) include the elderly, those with underlying health conditions, and those who have weakened immune systems.

15 Jul 2020

Promising new CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of the cancer cells.

15 Jul 2020

Study provides new insights into genetic susceptibility of COVID-19

A new Cleveland Clinic study has identified genetic factors that may influence susceptibility to COVID-19. Published today in BMC Medicine, the study findings could guide personalized treatment for COVID-19.

15 Jul 2020

Georgia State professor receives federal funding to study unique features of Ebola, Marburg viruses

Dr. Christopher Basler, professor and director of the Center for Microbial Pathogenesis in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.94 million federal grant to study unique features of Ebola and Marburg viruses that control how the virus family expresses its genes and escapes immune responses.

15 Jul 2020

RNA editing may repair the underlying cause of Rett Syndrome in mouse model

A genomic error that causes Rett Syndrome, a serious lifelong neurological disorder, can be corrected in the brains of mice by rewriting the genetic instructions carried by the RNA.

15 Jul 2020

Study identifies possible factors to predict severe toxicities in CAR T patients

Chimeric antigen receptor T-cell therapy (CAR T) has proved to be a valuable treatment option for patients with lymphoma who have failed other therapies. In clinical trials, the cellular immunotherapy was shown to provide durable remissions for nearly 40% of large B cell lymphoma patients.

15 Jul 2020

Nanotechnology plays major role in COVID-19 vaccine development

From mRNA vaccines entering clinical trials, to peptide-based vaccines and using molecular farming to scale vaccine production, the COVID-19 pandemic is pushing new and emerging nanotechnologies into the frontlines and the headlines.

15 Jul 2020

Gene News and Research

Latest Gene News and Research

Pembrolizumab can improve outcomes in patients with metastatic melanoma

Game-Changer: A SARS-CoV-2 serological test for 50-cents per sample!

Novel method for selecting the best drug therapy for cancer

Researchers unravel key mechanisms behind the mysteries of aging

Rare inherited mutation in TP53 gene confers risk of multiple cancers

Disseminated cancer cells hijack crucial iron micronutrients from native macrophages

Yale researchers uncover potential treatment for lethal Wolfram Syndrome

GW researcher receives $3.6 million to study HIV-1 resistance to antibody treatments

Study shows how parasitic bacteria cause lesions in the skin and internal organs

Study could accelerate drug development to reduce age-related diseases

Researchers solve the mystery of genetic defect in horses

Study shows how radiotherapy alters the behavior of immune cells in glioblastoma tumors

Researchers design new model to predict life expectancy of patients with Creutzfeldt‐Jakob disease

Study explains why fetuses and newborns are mostly spared by COVID-19

Promising new CAR T cell therapy results in exceptional patient recovery

Study provides new insights into genetic susceptibility of COVID-19

Georgia State professor receives federal funding to study unique features of Ebola, Marburg viruses

RNA editing may repair the underlying cause of Rett Syndrome in mouse model

Study identifies possible factors to predict severe toxicities in CAR T patients

Nanotechnology plays major role in COVID-19 vaccine development

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging