Gene News and Research

Latest Gene News and Research

Researchers claim SARS-CoV-2 B.1.1.7 variant likely to become globally dominant

The new variant of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) detected in England replicates more than two times faster than the earlier strains. This replication advantage promises to make it the dominant global variant very shortly. This finding comes from a startling preprint that appeared on the medRxiv* server in December 2020.

6 Jan 2021

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it.

5 Jan 2021

Researchers reveal distinct molecular signature in tumor tissues of Black breast cancer patients

A Roswell Park Comprehensive Cancer Center team led by Christine Ambrosone, PhD, and Song Yao, PhD, has revealed a distinct molecular signature in the tumor tissues of Black patients with breast cancer.

5 Jan 2021

Groundbreaking research project shows how brain health can traverse generations

Your father's exercise routine may have made you smarter according to EU-funded researchers studying how lifestyle choices affect brain function and memory. The findings could lead to new treatments for neurodegenerative conditions such as Alzheimer's disease.

5 Jan 2021

Replacing the RNA strand with DNA may enhance efficacy of ASO-based drugs

Antisense oligonucleotides (ASO) hold great promise for pharmacotherapy. Now, researchers at Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, advancing their earlier work on a heteroduplex oligonucleotide (HDO) model, have demonstrated augmentation of ASO-based drugs by replacing the RNA strand with DNA.

5 Jan 2021

Could asymptomatic SARS-CoV-2 screening in dental practices help prevent silent transmission?

Researchers conducted a mass, asymptomatic screening of patients in dental surgeries across Scotland to assess illustrate its potential utility in curbing silent transmission.

5 Jan 2021

A paper-based sensor for detecting COVID-19

News-Medical talks to Dipanjan Pan about the development of a paper-based electrochemical sensor that can detect COVID-19 in less than five minutes.

5 Jan 2021

Researchers develop detailed map of protein-protein interactions between SARS-CoV-2 and the host

By conducting a state-of-the-art interactome study between SARS-CoV-2 and host cells, researchers from the University of Texas MD Anderson Cancer Center in Houston identified 437 human proteins as the high-confidence interacting proteins – with substantial implications for understanding coronavirus disease 2019 (COVID-19) pathology and potential treatments.

5 Jan 2021

Neuroscientists track gene expression to gain insights into drug addiction, Parkinson's disease

Two MIT neuroscientists have received grants from the G. Harold and Leila Y. Mathers Foundation to screen for genes that could help brain cells withstand Parkinson's disease and to map how gene expression changes in the brain in response to drugs of abuse.

4 Jan 2021

Researchers resolve mysteries about the function of key gene-silencing protein

A long-running debate over how an important gene-silencing protein identifies its targets has been resolved by researchers at Massachusetts General Hospital (MGH).

4 Jan 2021

Researchers develop a gene signature for predicting survival in patients with peritoneal carcinomatosis

Researchers from The University of Texas MD Anderson Cancer Center who profiled more than 45,000 individual cells from patients with peritoneal carcinomatosis (PC), a specific form of metastatic gastric cancer, defined the extensive cellular heterogeneity and identified two distinct subtypes correlated with patient survival.

4 Jan 2021

Few organisms in the gut microbiome found to play a key role in type 2 diabetes

Researchers at Oregon State University have found that a few organisms in the gut microbiome play a key role in type 2 diabetes, opening the door to possible probiotic treatments for a serious metabolic disease affecting roughly one in 10 Americans.

4 Jan 2021

Epigenetic modulators have a rapid antidepressant-like effect, study shows

Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants.

4 Jan 2021

Tissue healing after brain injury could spur tumor growth

The healing process that follows a brain injury could spur tumor growth when new cells generated to replace those lost to the injury are derailed by mutations, Toronto scientists have found.

4 Jan 2021

FDA takes first steps in bringing clarity to emerging area of individualized drug development

Advances in scientific knowledge and drug development technology have provided an opportunity for new approaches to drug development, including the development of drugs for the treatment of rare diseases.

4 Jan 2021

Scientists discover cell responsible for triggering chronic, low-level inflammation in fat tissue

When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with obesity.

4 Jan 2021

Large transporter protein dysfunction associated with schizophrenia

Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens.

29 Dec 2020

Scientists trace genetic roots of Chiari 1 malformation

About one in 100 children has a common brain disorder called Chiari 1 malformation, but most of the time such children grow up normally and no one suspects a problem.

28 Dec 2020

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

A new study led by clinician-scientists from the National Cancer Centre Singapore, with collaborators from research institutions worldwide, has found that angiosarcomas have unique genomic and immune profiles which allow them to be classified into three different subtypes.

28 Dec 2020

Protein encourages similar developing cells to clump together

Tohoku University scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development.

24 Dec 2020

Gene News and Research

Latest Gene News and Research

Researchers claim SARS-CoV-2 B.1.1.7 variant likely to become globally dominant

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Researchers reveal distinct molecular signature in tumor tissues of Black breast cancer patients

Groundbreaking research project shows how brain health can traverse generations

Replacing the RNA strand with DNA may enhance efficacy of ASO-based drugs

Could asymptomatic SARS-CoV-2 screening in dental practices help prevent silent transmission?

A paper-based sensor for detecting COVID-19

Researchers develop detailed map of protein-protein interactions between SARS-CoV-2 and the host

Neuroscientists track gene expression to gain insights into drug addiction, Parkinson's disease

Researchers resolve mysteries about the function of key gene-silencing protein

Researchers develop a gene signature for predicting survival in patients with peritoneal carcinomatosis

Few organisms in the gut microbiome found to play a key role in type 2 diabetes

Epigenetic modulators have a rapid antidepressant-like effect, study shows

Tissue healing after brain injury could spur tumor growth

FDA takes first steps in bringing clarity to emerging area of individualized drug development

Scientists discover cell responsible for triggering chronic, low-level inflammation in fat tissue

Large transporter protein dysfunction associated with schizophrenia

Scientists trace genetic roots of Chiari 1 malformation

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

Protein encourages similar developing cells to clump together

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)