Gene News and Research

Latest Gene News and Research

Hypoxia signaling pathway could lead to COVID-19 treatments

Researchers in Spain have demonstrated that studying the hypoxia signaling pathway could provide opportunities for treating coronavirus disease 2019 (COVID-19).

12 Jan 2021

UTSW study uncovers a gene linked to growth of breast cancer

A team of UT Southwestern researchers has identified a gene involved in the growth of breast cancer, a finding that could lead to potential new targets for treatment.

12 Jan 2021

OXGENE introduces SLIM platform for discovery of antibodies against membrane proteins

OXGENE™ announces the introduction of its self-labelling integral membrane (SLIM™) protein discovery system.

12 Jan 2021

ARID1A gene in ovarian cancer plays a role in the regulation of metabolism

Mutations that inactivate the ARID1A gene in ovarian cancer increase utilization of the glutamine amino acid making cancer cells dependent on glutamine metabolism, according to a study by The Wistar Institute published online in Nature Cancer.

12 Jan 2021

Stress during pregnancy could affect the baby's chance of developing multiple diseases

Stress on an expectant mother could affect her baby's chance of developing disease - perhaps even over the course of the child's life, UC researchers have found.

12 Jan 2021

Mosaic mutations during embryonic development can cause autism spectrum disorder

Two studies in today's Nature Neuroscience, led by researchers at Boston Children's Hospital, Brigham and Women's Hospital (BWH), and Harvard Medical School (HMS), implicate mosaic mutations arising during embryonic development as a cause of autism spectrum disorder (ASD). The findings open new areas for exploring the genetics of ASD and could eventually inform diagnostic testing.

11 Jan 2021

Antibody recognition of linear SARS-CoV-2 epitopes preserved in mutated B.1.1.7 strain

In a recent medRxiv research paper, the US scientists examined the effects of non-synonymous mutations in the circulating B.1.1.7 strain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on linear antibody epitope signal for viral spike glycoprotein and nucleoprotein – and demonstrated that mutations should not result in immune evasion.

11 Jan 2021

Study monitors spatial shifts of liver gene expression in relationship to the circadian clock

Nothing in biology is static. Biological processes fluctuate over time, and if we are to put together an accurate picture of cells, tissues, organs etc., we have to take into account their temporal patterns. In fact, this effort has given rise to an entire field of study known as "chronobiology".

11 Jan 2021

Study sheds new light on the role of MLL4 gene in Kabuki syndrome

Scientists have known for years that mutations in the MLL4 gene can cause Kabuki syndrome, a rare developmental disorder.

11 Jan 2021

Master Regulator proteins control cancer transcriptional identity

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer's transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.

11 Jan 2021

Study finds association between severity of COVID-19 and shorter telomeres

Patients with severe COVID-19 disease have significantly shorter telomeres, according to a study conducted by researchers at the Spanish National Cancer Research Centre in collaboration with the COVID-IFEMA Field Hospital, published in the journal Aging.

11 Jan 2021

Study: 20% of glioblastomas are fueled by overactive mitochondria

A new study has found that up to 20% of glioblastomas--an aggressive brain cancer--are fueled by overactive mitochondria and may be treatable with drugs currently in clinical trials.

11 Jan 2021

Researchers identify biomarkers in sperm for paternal offspring autism susceptibility

Biomarkers in human sperm have been identified that can indicate a propensity to father children with autism spectrum disorder.

11 Jan 2021

Research opens up hope-filled possibilities for new autism therapies

Recent years have provided substantial research displaying the effect of genetic mutations on the development of autism and other neurodevelopmental disorders.

11 Jan 2021

Researchers receive NIH grant to develop more effective flu vaccines

To build better vaccines, scientists want to know more about how our bodies make adequate numbers of effective, durable antibodies against the influenza virus.

11 Jan 2021

Study shows how intestinal stem cells constantly renew and give rise to specialized cell types

The gut plays a central role in the regulation of the body's metabolism and its dysfunction is associated with a variety of diseases, such as obesity, diabetes, colitis and colorectal cancer that affect millions of people worldwide.

11 Jan 2021

Study shows P681H mutation is becoming globally prevalent among SARS-CoV-2 sequences

In a recent bioRxiv preprint study, researchers from the University of Hawaii showed that the S gene of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuously mutating according to the sequence and phylogenetic analysis.

10 Jan 2021

Gene therapy can effectively treat mice with tuberous sclerosis complex, shows study

Patients with tuberous sclerosis complex, a genetic disorder characterized by the growth of noncancerous tumors in multiple organs of the body, have limited treatment options.

8 Jan 2021

UCSF researchers discover a new way to control immune system's 'natural killer' cells

UC San Francisco scientists have discovered a new way to control the immune system's "natural killer" (NK) cells, a finding with implications for novel cell therapies and tissue implants that can evade immune rejection.

8 Jan 2021

Study shows how new antibiotic resistance genes arise from random DNA sequences

An important and still unanswered question is how new genes that cause antibiotic resistance arise. In a new study, Swedish and American researchers have shown how new genes that produce resistance can arise from completely random DNA sequences. The results have been published in the journal PLOS Genetics.

8 Jan 2021

Gene News and Research

Latest Gene News and Research

Hypoxia signaling pathway could lead to COVID-19 treatments

UTSW study uncovers a gene linked to growth of breast cancer

OXGENE introduces SLIM platform for discovery of antibodies against membrane proteins

ARID1A gene in ovarian cancer plays a role in the regulation of metabolism

Stress during pregnancy could affect the baby's chance of developing multiple diseases

Mosaic mutations during embryonic development can cause autism spectrum disorder

Antibody recognition of linear SARS-CoV-2 epitopes preserved in mutated B.1.1.7 strain

Study monitors spatial shifts of liver gene expression in relationship to the circadian clock

Study sheds new light on the role of MLL4 gene in Kabuki syndrome

Master Regulator proteins control cancer transcriptional identity

Study finds association between severity of COVID-19 and shorter telomeres

Study: 20% of glioblastomas are fueled by overactive mitochondria

Researchers identify biomarkers in sperm for paternal offspring autism susceptibility

Research opens up hope-filled possibilities for new autism therapies

Researchers receive NIH grant to develop more effective flu vaccines

Study shows how intestinal stem cells constantly renew and give rise to specialized cell types

Study shows P681H mutation is becoming globally prevalent among SARS-CoV-2 sequences

Gene therapy can effectively treat mice with tuberous sclerosis complex, shows study

UCSF researchers discover a new way to control immune system's 'natural killer' cells

Study shows how new antibiotic resistance genes arise from random DNA sequences

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)