Gene News and Research

Latest Gene News and Research

Additional data demonstrates positive results of pridopidine drug on Total Functional Capacity

Positive results from additional analyses of PRIDE-HD and Open-HART trials with pridopidine published in a peer-reviewed journal, The Journal of Huntington's Disease.

17 Dec 2020

Researchers identify key gene necessary for cells to consume and destroy viruses

A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve the immune system's ability to combat viral infections, such as those fueling the ongoing COVID-19 pandemic.

17 Dec 2020

FAT1 mutations act as tumor suppressor and prevent cancer development, indicates study

Cancer metastasis, which is the dissemination of tumor cells into distant organs, is the leading cause of mortality in cancer patients. To undergo metastasis, cells must leave the primary tumor, circulate into the blood, colonize distant organs, and form distant metastasis.

17 Dec 2020

Specific genetic target could help explain the variation in COVID-19 effects

The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become.

17 Dec 2020

Study shows how melanomas assist T cells from identifying and killing tumor cells

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

17 Dec 2020

Researchers identify neurons that regulate nausea-like responses in mice

At some point, everyone experiences nausea. Whether it occurs after unwisely eating a week-old slice of pizza or as an accompaniment to a serious infection, that queasy, unsettling sensation centered around the stomach is a signal that something is amiss within the body and typically portends a bout of vomiting.

17 Dec 2020

Researchers explain the role of enzyme that facilitates appropriate development of mouse embryo

The body plan of an organism, crafted over millennia of evolutionary trial and error, is so exquisitely fine-tuned that even a subtle deviation can be detrimental to individual survival and reproductive success.

17 Dec 2020

Researchers examine proteins involved in SARS-CoV-2 infection

Like all viruses, the novel coronavirus is dependent on help from the human host cell. Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate.

17 Dec 2020

Brain protein indicates a link between circadian rhythm dysfunction and Alzheimer's Disease

Fractured sleep, daytime sleepiness and other signs of disturbance in one's circadian rhythm are common complaints of people with Alzheimer's disease, and the problems only get worse as the disease progresses.

17 Dec 2020

Researchers use bacterial strains to measure host gene expression in mouse model

The bacteria Streptococcus pneumoniae colonizes the nasopharynx and can cause pneumonia. Then, it can spread from the lungs to the bloodstream and cause organ damage.

16 Dec 2020

A new approach to identify genomic regions in our brain that contribute to make us human

With only 1% difference, the human and chimpanzee protein-coding genomes are remarkably similar.

16 Dec 2020

Clemson grad student focuses on studying how genes interact in a normal brain

You must first understand how something works normally before you can figure out why it's broken.

16 Dec 2020

Scientists identify new Salmonella proteins

Salmonella are bacteria that can cause food poisoning with severe diarrhea. If they penetrate from the intestine into the blood system, this can lead to sepsis, life-threatening inflammatory reactions in the entire organism.

16 Dec 2020

Autoimmune condition biomarkers promote SARS-CoV-2 viral entry, study finds

Researchers have reported that the autoimmune PTPN2 risk variant rs1893217 promotes the expression of the SARS-CoV-2 receptor, ACE2, and thus promotes cellular entry, which is mediated by SARS-CoV-2 spike S protein.

16 Dec 2020

New data shows encouraging results for patients with neuro-degenerative blinding eye disease

New data published in the Journal Science Translational Medicine shows encouraging results in a worldwide clinical trial for patients diagnosed with the neuro-degenerative blinding eye disease; Leber Hereditary Optic Neuropathy (LHON.)

16 Dec 2020

Researchers identify adenovirus gene therapy for placental insufficiency

A new study identified an adenovirus gene therapy vector carrying a VEGF isoform. It can improve uterine blood flow in placental insufficiency, as reported in the peer-reviewed journal Human Gene Therapy.

15 Dec 2020

Neanderthal gene variant increases risk of severe COVID-19

Researchers in Germany have conducted a study showing that between 2 and 8% of people in Eurasia carry a genetic variant inherited from Neanderthals that significantly increases the risk of becoming critically ill with coronavirus disease 2019 (COVID-19).

15 Dec 2020

Research could lead to potential new treatments for mutant RAS-driven cancers

Scientists have dedicated huge amounts of time and resources to better understanding the causes and mechanisms of cancer growth.

15 Dec 2020

Tumor's stiff-arm tactic limits the effectiveness of immunotherapeutics

In a paper just published in the Journal for the Immunotherapy of Cancer (doi:10.1136/jitc-2020-001712), Dr Herbert, Head of Discovery at InsideOutBio, asks whether cancer cells stiff-arm immune cells just like rugby players push off defenders from the other team.

15 Dec 2020

Genomic and immune indicators can help identify prostate cancer patients at high risk of lethal outcomes

Prostate cancer is one of the most common cancers among men in the United States. One in nine men will be diagnosed during his lifetime.

15 Dec 2020

Gene News and Research

Latest Gene News and Research

Additional data demonstrates positive results of pridopidine drug on Total Functional Capacity

Researchers identify key gene necessary for cells to consume and destroy viruses

FAT1 mutations act as tumor suppressor and prevent cancer development, indicates study

Specific genetic target could help explain the variation in COVID-19 effects

Study shows how melanomas assist T cells from identifying and killing tumor cells

Researchers identify neurons that regulate nausea-like responses in mice

Researchers explain the role of enzyme that facilitates appropriate development of mouse embryo

Researchers examine proteins involved in SARS-CoV-2 infection

Brain protein indicates a link between circadian rhythm dysfunction and Alzheimer's Disease

Researchers use bacterial strains to measure host gene expression in mouse model

A new approach to identify genomic regions in our brain that contribute to make us human

Clemson grad student focuses on studying how genes interact in a normal brain

Scientists identify new Salmonella proteins

Autoimmune condition biomarkers promote SARS-CoV-2 viral entry, study finds

New data shows encouraging results for patients with neuro-degenerative blinding eye disease

Researchers identify adenovirus gene therapy for placental insufficiency

Neanderthal gene variant increases risk of severe COVID-19

Research could lead to potential new treatments for mutant RAS-driven cancers

Tumor's stiff-arm tactic limits the effectiveness of immunotherapeutics

Genomic and immune indicators can help identify prostate cancer patients at high risk of lethal outcomes

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)