Gene News and Research

Latest Gene News and Research

Researchers create new tool to identify cancer-causing mutations lurking in 98% of the genome

Gene coding regions constitute 2% of the human genome. St. Jude Children's Research Hospital scientists have developed a computational tool to identify alterations that drive tumor formation in the remaining 98% of the genome.

6 Jul 2020

Clemson researcher receives DOD grant to explore cellular underpinnings of developmental disorder

College of Science associate professor and researcher David Feliciano has received a $667,000 grant from the Department of Defense to explore the cellular underpinnings of Tuberous Sclerosis Complex (TSC), a developmental disorder characterized by the growth of benign tumors throughout the body, most notably in the brain.

6 Jul 2020

Easy-to-use software developed to identify drug-resistant genes in bacteria

Washington State University researchers have developed an easy-to-use software program to identify drug-resistant genes in bacteria.

6 Jul 2020

Study reveals key role of a protein in regulating scar tissue growth after heart attacks

New UCLA research conducted in mice could explain why some people suffer more extensive scarring than others after a heart attack.

6 Jul 2020

New strategies can help increase the efficiency of artificial cell reprogramming

Maria-Elena: Can you imagine being able to artificially generate cells that can develop into any cell type? That would be really fantastic! We call this ability 'totipotency' and it is the highest level of cellular plasticity.

6 Jul 2020

Researchers use optogenetics to successfully induce arm movements in monkeys

Optogenetics is a recently developed technique that can control cellular functions by illuminating lights to the cells in which light-sensitive proteins are expressed by gene transfer.

6 Jul 2020

Using machine learning to analyze the interaction of breast cancer risk factors

A recently published article from University of Eastern Finland and Kuopio University Hospital reports new innovative use of machine learning to help understand the interplay of genetic and other breast cancer risk factors.

6 Jul 2020

NPHS1 is a disease-susceptibility gene for steroid-sensitive nephrotic syndrome, reveals study

An international research collaboration, including Professor IIJIMA Kazumoto et al. (of the Department of Pediatrics, Kobe University Graduate School of Medicine) has revealed that NPHS1 is a disease-susceptibility gene for steroid-sensitive nephrotic syndrome in children.

3 Jul 2020

Newly discovered endometrial cancer biomarker enables early detection and treatment

A newly discovered endometrial (uterine) cancer biomarker and diagnostic method will enable detection of the tumor type that is likely to spread and recur so that clinicians can initiate treatment early and stop the cancer from attacking other parts of the body.

3 Jul 2020

New editorial published following adverse events of gene therapy clinical trial

The Editor-in-Chief of Human Gene Therapy, the first journal devoted to the field of gene therapy, and one of the world's leading experts on gene therapy have co-authored a new editorial, Moving Forward After Two Deaths in a Gene Therapy Trial of Myotubular Myopathy, in response to the news of two deaths in a now-halted gene therapy clinical trial.

3 Jul 2020

Diagnosis of COVID-19 by RT-LAMP assay in 25 minutes

Even as COVID-19 continues its inexorable march, taking hundreds of thousands of lives and causing nearly 11 million cases, the diagnosis of the infection is still not sensitive or specific enough. Now, a new study by scientists at the Francis Crick Institute and published on the preprint server medRxiv...

3 Jul 2020

UCLA scientists identify new function for histones

UCLA scientists have identified a new function for histones, the spool-shaped proteins that regulate gene expression and serve as anchors for strands of DNA to wrap around.

2 Jul 2020

Researchers discover new candidate for raw material synthesis through gene transfer

Cyanobacteria hardly need any nutrients and use the energy of sunlight. Bathers are familiar with these microorganisms - often incorrectly called "blue-green algae" - as they often occur in waters.

2 Jul 2020

New platform helps investigate harmful effects of microplastics and nanoplastics

Plastic pollution is a critical environmental issue facing the world today, yet the impact of all the microplastics (MPs) and nanoplastics (NPs) that have seeped into the food and beverage supply on human health is an "undervalued avenue of research," according to the team behind a revealing new study released today in STEM CELLS.

2 Jul 2020

Researchers unravel how the body fights off urinary tract infections

Anyone who has ever had cystitis knows that urinary tract infections of this kind are annoying and painful. They can be well treated by antibiotics, but may be fatal if left untreated.

2 Jul 2020

Study identifies a promising way to delay the onset of Alzheimer's disease

Currently we are facing a dementia epidemic, estimations showing that by 2050 approximately 131 million people will be affected. Every 7 seconds a patient is diagnosed worldwide.

2 Jul 2020

Studies show how individual cells maintain their internal clocks

Two new studies led by UT Southwestern scientists outline how individual cells maintain their internal clocks, driven both through heritable and random means.

2 Jul 2020

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

An interview discussing the use of spherical nucleic acids (SNAs) and what they show about the importance of structure in pharmaceutical development.

From Pittcon 2 Jul 2020

SARS-CoV-2 infection modeling in iPSC-derived type 2 cells

The most fatal form of COVID-19 disease is acute respiratory distress syndrome (ARDS), caused by direct viral injury as well as indirect noxious effects caused by cytotoxic chemicals and inflammatory processes. A new study published on the preprint server bioRxiv* in June 2020 shows that this is partly due to the rapid onset of inflammation caused by the infection of type 2 alveolar cells with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Jul 2020

Repurposed drug for acute lung injury in COVID-19

Now, a new study addresses the possible use of an FDA-approved monoclonal antibody, called fostamatinib, a spleen tyrosine kinase inhibitor (SYK), to reduce the levels of mucin-1, a molecule associated with acute lung injury and acute respiratory distress syndrome (ARDS). People who have severe COVID-19 disease may develop ARDS.

2 Jul 2020

Gene News and Research

Latest Gene News and Research

Researchers create new tool to identify cancer-causing mutations lurking in 98% of the genome

Clemson researcher receives DOD grant to explore cellular underpinnings of developmental disorder

Easy-to-use software developed to identify drug-resistant genes in bacteria

Study reveals key role of a protein in regulating scar tissue growth after heart attacks

New strategies can help increase the efficiency of artificial cell reprogramming

Researchers use optogenetics to successfully induce arm movements in monkeys

Using machine learning to analyze the interaction of breast cancer risk factors

NPHS1 is a disease-susceptibility gene for steroid-sensitive nephrotic syndrome, reveals study

Newly discovered endometrial cancer biomarker enables early detection and treatment

New editorial published following adverse events of gene therapy clinical trial

Diagnosis of COVID-19 by RT-LAMP assay in 25 minutes

UCLA scientists identify new function for histones

Researchers discover new candidate for raw material synthesis through gene transfer

New platform helps investigate harmful effects of microplastics and nanoplastics

Researchers unravel how the body fights off urinary tract infections

Study identifies a promising way to delay the onset of Alzheimer's disease

Studies show how individual cells maintain their internal clocks

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

SARS-CoV-2 infection modeling in iPSC-derived type 2 cells

Repurposed drug for acute lung injury in COVID-19

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging