Gene News and Research

Latest Gene News and Research

Hokkaido University scientists reveal missing link in rare inherited skin disease

Hokkaido University scientists are getting closer to understanding how a rare hereditary disease impairs the skin's barrier function, which determines how well the skin is protected.

29 Jan 2020

Research uncovers disease-aggravating mutation in mouse model of GRACILE syndrome

The new mitochondrial DNA (mtDNA) variant drastically speeds up the disease progression in a mouse model of GRACILE syndrome. This discovery provides a new tool for studies of mitochondrial diseases.

29 Jan 2020

New way to treat stroke using an already FDA-approved drug shows promise

Stroke is the third leading cause of death and disability in the United States. More than 87 percent are ischemic strokes, caused by obstruction of one or more cerebral arteries. With limited progress in developing treatments, there is a critical need for neuroprotective agents to effectively treat stroke.

29 Jan 2020

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

Using genetically engineered human pluripotent stem cells, University of California San Diego School of Medicine researchers created a new type of cancer model to study in vivo how glioblastoma, the most common and aggressive form of brain cancer, develops and changes over time.

29 Jan 2020

Scientists 'knock out' gene in myeloid cells to create listeriosis-immune mice

An international research team which includes specialists from ITMO University has conducted a series of experiments with the goal of studying the immune system and identifying the genes and proteins involved in the response to certain harmful bacteria.

28 Jan 2020

Bone marrow chip provides new strategy for understanding Shwachman-Diamond syndrome

A new research tool that mimics the behavior of diseased bone marrow provides a new strategy for understanding the bone marrow disease, Shwachman-Diamond syndrome, and hopefully, developing new treatments.

28 Jan 2020

Successful gene therapy trial in patients with X-linked Chronic Septic Granulomatosis

American and British teams led by Drs Kohn (University of California, Los Angeles), Malech (NIH), Williams (Boston Children's) and Trasher (Great Ormond Street Institute of Child Health) published yesterday in Nature Medicine the conclusive results of a gene therapy trial conducted in the United States and Great Britain in 9 patients with X-linked Chronic Septic Granulomatosis (X-CGD), a rare and severe immune dysfunction. Six of them are free of treatment for complications generated by the disease.

28 Jan 2020

Study on axolotl's ability to regenerate might help find ways to restore damaged tissue in humans

The type of salamander called axolotl, with its frilly gills and widely spaced eyes, looks like an alien and has other-worldly powers of regeneration. Lose a limb, part of the heart or even a large portion of its brain? No problem: They grow back.

28 Jan 2020

Researchers discover how CDK8 oncogene gets activated in healthy humans

Most cancers are caused by a large variety of factors that vary from one person to another. To unravel this complexity, genes that contribute to the development of a respective cancer must be identified. Such genes are called oncogenes. A good example of an oncogene is CDK8: Cyclin-dependent kinase 8.

28 Jan 2020

New study of genes in Asian populations may help better understand, treat genetic diseases

An ambitious new study of genes in Asian populations is filling in big gaps in our understanding of human genetics, shedding light on the history of human migration and ultimately aiming to improve our ability to treat disease.

28 Jan 2020

New AI tool predicts disease progression and evolution in neurodegenerative disorders

Researchers have found that testing blood using an artificial intelligence algorithm successfully predicted disease progression in neurodegenerative disorders.

28 Jan 2020

Low-protein diet throughout pregnancy and lactation may increase risk of liver damage

A study in rats examines a pathway through which protein deficiency during pregnancy leads to fat accumulation in the liver and increased risk of liver damage.

28 Jan 2020

Scientists may soon be able to prevent disease-spreading mosquitoes from maturing

New research from UC Riverside shows scientists may soon be able to prevent disease-spreading mosquitoes from maturing. Using the same gene-altering techniques, they may also be able help boost reproduction in beneficial bumblebees.

28 Jan 2020

AI analysis of blood samples can predict progression of neurodegenerative disease

Evaluating the effectiveness of therapies for neurodegenerative diseases is often difficult because each patient's progression is different.

28 Jan 2020

Study finds unexpected response to estrogen at the single cell level

A team led by researchers at Baylor College of Medicine found that not only do individual mammalian cells in a population fail to respond synchronously to estrogen stimulation, neither do individual gene copies, known as alleles.

28 Jan 2020

New gene correction therapy for hereditary muscular disease among children

Duchenne type muscular dystrophy is the most common hereditary muscular disease among children, leaving them wheelchair-bound before the age of twelve and reducing life expectancy.

27 Jan 2020

Researchers develop new isolated limb infusion method for melanoma treatment

Worldwide, the incidence rates of skin cancer, like other types of cancer, is increasing. People in Europe and the Nordic countries are, compared to other areas of the world, at a higher risk of developing skin cancer due to their predominantly light and sun-sensitive skin type. The number of new cases of cancer in Estonia and Nordic countries has reached the same level as in sunny Australia, New Zealand and Florida. The increasing trend among Estonians to travel to southern counties is also likely to play a role in this.

27 Jan 2020

Expert genomics panel disputes certain genes linked to a dangerous heart condition

A panel of experts have said that nine genes linked to a dangerous heart disorder called long QT syndrome, are not associated with the condition.

27 Jan 2020

Study tracks milestones in the history of human disease genetics

Genetic discoveries over the past 25 years have substantially advanced understanding of both rare and common diseases, furthering the development of treatment and prevention for ailments ranging from inflammatory bowel diseases to diabetes, according to a study published in Nature Research in January.

27 Jan 2020

ClinGen expert panel disputes nine genes linked to long QT syndrome

Geneticists and heart specialists around the world had previously reported 17 genes to cause long QT syndrome, a little-known inherited heart condition. However, the Clinical Genome Resource's expert panel has critically reevaluated the scientific evidence for all 17 reported genes, disputing nine of the genes and revealing only three of the genes to be definitively associated with the most common form of the disease.

27 Jan 2020

Gene News and Research

Latest Gene News and Research

Hokkaido University scientists reveal missing link in rare inherited skin disease

Research uncovers disease-aggravating mutation in mouse model of GRACILE syndrome

New way to treat stroke using an already FDA-approved drug shows promise

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

Scientists 'knock out' gene in myeloid cells to create listeriosis-immune mice

Bone marrow chip provides new strategy for understanding Shwachman-Diamond syndrome

Successful gene therapy trial in patients with X-linked Chronic Septic Granulomatosis

Study on axolotl's ability to regenerate might help find ways to restore damaged tissue in humans

Researchers discover how CDK8 oncogene gets activated in healthy humans

New study of genes in Asian populations may help better understand, treat genetic diseases

New AI tool predicts disease progression and evolution in neurodegenerative disorders

Low-protein diet throughout pregnancy and lactation may increase risk of liver damage

Scientists may soon be able to prevent disease-spreading mosquitoes from maturing

AI analysis of blood samples can predict progression of neurodegenerative disease

Study finds unexpected response to estrogen at the single cell level

New gene correction therapy for hereditary muscular disease among children

Researchers develop new isolated limb infusion method for melanoma treatment

Expert genomics panel disputes certain genes linked to a dangerous heart condition

Study tracks milestones in the history of human disease genetics

ClinGen expert panel disputes nine genes linked to long QT syndrome

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging