Gene News and Research

Latest Gene News and Research

EZH2 mutations can be used as marker for diagnosing different types of cancers

Inside the cell, DNA is tightly wrapped around proteins and packed in a complex, 3D structure that we call "chromatin".

29 Jan 2019

Review paper on transformative potential of precision and personalized medicine for cancer treatment

In a paper published in the September/December 2018 issue of TECHNOLOGY, a group of researchers from Rutgers University Department of Biomedicine Engineering have published a review paper on the transformative potential of precision and personalized medicine (PPM) for cancer treatment.

29 Jan 2019

NIH grants awarded to Nanoscope to recruit talent and develop optogenetic delivery platforms

Retinal dystrophies such as Age-related macular degeneration (AMD) are a major cause of vision loss in aging populations. National Eye Institute (NEI) estimates that the prevalence of advanced AMD will grow to nearly 3 million by 2020.

29 Jan 2019

New class of antisense oligonucleotide therapeutics tested in humans

A first-in-human study with a new class of antisense oligonucleotide therapeutics showed the ability to target the RNA-silencing drug to the liver, resulting in improved potency and safety at therapeutic doses. The design and results of this trial, conducted in healthy human volunteers are reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Jan 2019

Antibiotic-resistant superbugs have reached the Arctic

An international team of researchers has identified antibiotic-resistant genes (ARGs) in an area of the arctic that have spread from urban India.

28 Jan 2019

Stress and paradoxical sleep associated with pathways of brain cell death and survival

The first and most distinct consequence of daily mild stress is an increase in rapid-eye-movement (REM) sleep, a new study in the journal PNAS reports. The research also demonstrated that this increase is associated with genes involved in cell death and survival.

28 Jan 2019

Mechanism of inflammation initiation through NLRP3 inflammasome activation revealed

Inflammation is the response of our immune system to infection and harmful environmental effects. On one hand, it is beneficial as it defends our body against microbes. On the other hand, excessive inflammation leads to serious diseases.

28 Jan 2019

Study identifies new genetic variant associated with ARDS

An international study in which Javier Belda, Professor of Surgery at the University of Valencia and Incliva researcher, participated, has identified a new genetic variant associated with Acute Respiratory Distress Syndrome.

28 Jan 2019

Researchers discover immune regulator that appears to dictate glioblastoma

Researchers at The University of Texas MD Anderson Cancer Center have discovered an immune regulator that appears to dictate glioblastoma progression by shutting down immune surveillance, indicating a potential new area of therapeutic investigation.

28 Jan 2019

Gluten-free wheat can be produced for people with celiac disease by using gene editing

One to two per cent of the population has Celiac Disease (CD), an immune reaction to gluten. Wheat grains contain gluten, a mixture of glutenin and gliadin proteins, which build a network that gives wheat bread its unique properties and quality.

28 Jan 2019

'Antibiotic-Resistant Genes' found in one of the last pristine places on earth

Antibiotic-Resistant Genes that were first detected in urban India have been found 8,000 miles away in one of the last 'pristine' places on earth, a new study has shown.

28 Jan 2019

Researchers create synthetic growth factor that offers comparable biological response

Growth factors are ligands that play important roles in the body - they are responsible for tissue regeneration, wound healing, and the maintenance and growth of cells.

28 Jan 2019

Regular use of aspirin may help some patients survive head and neck cancer

Regular use of aspirin or other nonsteroidal anti-inflammatory drugs may help some patients with head and neck cancer survive the disease, according to a study led by Professor Jennifer Grandis at the University of California, San Francisco.

27 Jan 2019

Scientists pinpoint mechanism that leads to steroid diabetes

Patients undergoing long-term treatment with steroids may suffer from metabolic side effects. Researchers at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich, partners in the German Center for Diabetes Research, have now pinpointed a mechanism that leads to so-called steroid diabetes

25 Jan 2019

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Regular use of a common type of medication, such as aspirin and ibuprofen, significantly improves survival for a third or more patients with head and neck cancer, a new study led by UC San Francisco has found.

25 Jan 2019

Fish oil does not appear to provide therapeutic benefits for obese teens with uncontrolled asthma

Fish oil does not appear to improve asthma control in adolescents and young adults with uncontrolled asthma who are overweight or obese, according to new research published online in the Annals of the American Thoracic Society.

25 Jan 2019

Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

An open label Phase 3 study conducted at Ann & Robert H. Lurie Children's Hospital of Chicago and other centers established that a combination of cystic fibrosis drugs lumacaftor and ivacaftor is safe and effective in children aged 2-5 years, whose disease is caused by two copies of F508del-CFTR gene mutation - the most common and severe form of cystic fibrosis.

25 Jan 2019

Discovery could guide future treatments for patients with hypertension

A team of Vanderbilt University Medical Center researchers, working with the U.S. Department of Veteran's Affairs, has discovered genetic associations with blood pressure that could guide future treatments for patients with hypertension.

25 Jan 2019

Understanding healing role for kidney-resident macrophages may help treat acute kidney injury

During development in the womb, immune cells called macrophages go to the kidneys, and they remain there for life. Understanding the possible healing role for these macrophages after kidney damage may be crucial to helping treat patients who suffer acute kidney injury.

25 Jan 2019

PET imaging post-HBOT shows improvement in brain metabolism in Alzheimer’s disease

Dr. Paul Harch, Clinical Professor and Director of Hyperbaric Medicine at LSU Health New Orleans School of Medicine, and Dr. Edward Fogarty, Chairman of Radiology at the University of North Dakota School of Medicine, report the first PET scan-documented case of improvement in brain metabolism in Alzheimer's disease in a patient treated with hyperbaric oxygen therapy.

24 Jan 2019

Gene News and Research

Latest Gene News and Research

EZH2 mutations can be used as marker for diagnosing different types of cancers

Review paper on transformative potential of precision and personalized medicine for cancer treatment

NIH grants awarded to Nanoscope to recruit talent and develop optogenetic delivery platforms

New class of antisense oligonucleotide therapeutics tested in humans

Antibiotic-resistant superbugs have reached the Arctic

Stress and paradoxical sleep associated with pathways of brain cell death and survival

Mechanism of inflammation initiation through NLRP3 inflammasome activation revealed

Study identifies new genetic variant associated with ARDS

Researchers discover immune regulator that appears to dictate glioblastoma

Gluten-free wheat can be produced for people with celiac disease by using gene editing

'Antibiotic-Resistant Genes' found in one of the last pristine places on earth

Researchers create synthetic growth factor that offers comparable biological response

Regular use of aspirin may help some patients survive head and neck cancer

Scientists pinpoint mechanism that leads to steroid diabetes

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Fish oil does not appear to provide therapeutic benefits for obese teens with uncontrolled asthma

Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

Discovery could guide future treatments for patients with hypertension

Understanding healing role for kidney-resident macrophages may help treat acute kidney injury

PET imaging post-HBOT shows improvement in brain metabolism in Alzheimer’s disease

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging