Gene News and Research

Latest Gene News and Research

OGT develops targeted NGS panel for constitutional cytogenetics research

Oxford Gene Technology, A Sysmex Group Company, has developed a breakthrough targeted NGS panel for constitutional cytogenetics research. The new CytoSure NGS panel—launching early in 2020—will combine the strengths of microarrays and NGS to deliver a comprehensive all-in-one assay.

From Oxford Gene Technology 11 Dec 2019

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

A genetic variant in the gene transthyretin (TTR)- which is found in about 3 percent of individuals of African ancestry- is a more significant cause of heart failure than previously believed, according to a multi-institution study led by researchers at Penn Medicine.

10 Dec 2019

Online decision aid provides more knowledge about the benefits of genomic sequencing

A decision aid developed to support patients undergoing genomic sequencing can reduce the amount of time patients spend speaking with overburdened genetic counselors while helping them were more knowledgeable about the benefits of sequencing, suggests a study from St. Michael's Hospital.

10 Dec 2019

Huntington's disease patients need to better understand the risks and benefits of new therapies

For patients with Huntington's disease (HD), clinical trials can offer hope when there are no treatments available despite unknowns about whether the therapy will work or is safe.

10 Dec 2019

Researchers find another piece of puzzle relating to bird flu viruses

Normally, bird flu viruses do not spread easily from person to person. But if this does happen, it could trigger a pandemic. Researchers from the MDC and RKI have now explained in the journal Nature Communications what makes the leap from animals to humans less likely.

10 Dec 2019

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

10 Dec 2019

A network approach to explore the causes of IBD

Diseases of the gut are often notoriously difficult to diagnose, nevermind understand, which is where a network-based approach comes in.

10 Dec 2019

ERC promotes CRISPR research to better treat infections

Chase Beisel heads the "Synthetic Biology of RNA" research group at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, a branch of the Helmholtz Centre for Infection Research in Braunschweig and run in collaboration with the Julius-Maximilians-Universität in Würzburg.

10 Dec 2019

New study uncovers the genetic basis of memory

New research has uncovered the genetic basis for different functions of memory.

10 Dec 2019

Genetic alteration increases risk of Autism and Tourette's impacts on the brain

Lancaster University researchers have discovered, for the first time, how a genetic alteration that increases the risk of developing Autism and Tourette's impacts on the brain.

10 Dec 2019

Study reveals new mechanism that contributes to bone maintenance and repair

Led by researchers at Baylor College of Medicine, a study published in the journal Cell Stem Cell reveals a new mechanism that contributes to adult bone maintenance and repair and opens the possibility of developing therapeutic strategies for improving bone healing.

9 Dec 2019

Pairing chemotherapy azacitidine with enasidenib boosts complete remission in AML patients

A multi-institutional, Phase II study led by The University of Texas MD Anderson Cancer Center showed that pairing standard chemotherapy azacitidine (AZA) with a drug called enasidenib (ENA) measurably boosts complete remission in patients newly diagnosed with a specific form of acute myeloid leukemia (AML).

9 Dec 2019

Metformin shows benefits on aging and different diseases

Researchers at McMaster University have unlocked one of the secrets behind the many benefits of metformin.

9 Dec 2019

Some phages employ new strategy to avoid becoming the next casualty of DNA-dicing enzymes

Bacteria and the viruses that infect them are engaged in a molecular arms race as ancient as life itself. Evolution has equipped bacteria with an arsenal of immune enzymes, including CRISPR-Cas systems, that target and destroy viral DNA. But bacteria-killing viruses, also known as phages, have devised their own tools to help them outmaneuver even the most formidable of these bacterial defenses.

9 Dec 2019

Study shows how a new combination approach helps overcome resistance to cancer immunotherapy

Cancer immunology drugs, which harness the body's immune system to better attack cancer cells, have significantly changed the face of cancer treatment. People with aggressive cancers are now living longer, healthier lives. Unfortunately, cancer immunology therapy only works in a subset of patients.

9 Dec 2019

Researchers identify key protein associated with aging

Aging is a dramatic public health issue in the face of the current demographic changes: the proportion of 60 and over in the world's population will almost double by 2050. In this context, a new discovery has just broadened scientific knowledge.

9 Dec 2019

New partnership enables launch of POCare cell therapy platform within HYGEIA Group’s hospital network

Orgenesis Inc., a leading cell and gene therapy enabling company providing centralized CDMO manufacturing and development services through its subsidiary Masthercell Global, Inc., as well as localized point-of-care development and processing centers for therapeutic treatments, today announces a strategic partnership agreement between the HYGEIA Group and the Theracell–Orgenesis joint venture.

9 Dec 2019

Study shows safety of palbociclib for advanced breast cancer patients with unique gene alteration

Women who receive palbociclib (Ibrance) to treat their advanced breast cancer and have a gene alteration that can lead to a condition known as benign ethnic neutropenia (BEN), can safely receive the drug without major concerns of developing infections associated with neutropenia, or low white blood cell counts, say Georgetown Lombardi Comprehensive Cancer Center researchers.

9 Dec 2019

New startup aims to prevent reperfusion-related organ damage after liver transplant

Roughly 65 years ago, the first human organ transplant was successfully performed. A decade later, heart and liver transplants became possible. Now, a startup founded by researchers from the Medical University of South Carolina and elsewhere hopes to bring about the next major breakthrough.

8 Dec 2019

New technique holds promise in cancer research and science studies

A new technique reported this week in Science overcomes several limitations of typical high-throughput chemical screens conducted on cell samples. Such screens are commonly used to try to discover new cancer drugs, and in many other biomedical applications.

8 Dec 2019

Gene News and Research

Latest Gene News and Research

OGT develops targeted NGS panel for constitutional cytogenetics research

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

Online decision aid provides more knowledge about the benefits of genomic sequencing

Huntington's disease patients need to better understand the risks and benefits of new therapies

Researchers find another piece of puzzle relating to bird flu viruses

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

A network approach to explore the causes of IBD

ERC promotes CRISPR research to better treat infections

New study uncovers the genetic basis of memory

Genetic alteration increases risk of Autism and Tourette's impacts on the brain

Study reveals new mechanism that contributes to bone maintenance and repair

Pairing chemotherapy azacitidine with enasidenib boosts complete remission in AML patients

Metformin shows benefits on aging and different diseases

Some phages employ new strategy to avoid becoming the next casualty of DNA-dicing enzymes

Study shows how a new combination approach helps overcome resistance to cancer immunotherapy

Researchers identify key protein associated with aging

New partnership enables launch of POCare cell therapy platform within HYGEIA Group’s hospital network

Study shows safety of palbociclib for advanced breast cancer patients with unique gene alteration

New startup aims to prevent reperfusion-related organ damage after liver transplant

New technique holds promise in cancer research and science studies

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

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