Gene News and Research

Latest Gene News and Research

Human iPS cell-derived inner ear cells may improve hereditary hearing loss

A Japanese research group has successfully grafted human iPS cell-derived inner ear cells that express human-derived proteins into the inner ears of embryonic mice.

8 Feb 2018

Special protein improves survival and lung function of mice with influenza, study shows

GM-CSF, a protein that modifies the immune response to the flu, may also help reduce lung inflammation and improve survival during influenza, according to Penn State researchers.

8 Feb 2018

International research collaboration finds genetic mutation linked to Crohn's disease

A genetic mutation was found to be associated with Crohn's disease. The discovery was made by international research collaboration and was published in the prestigious journal Science Translational Medicine.

8 Feb 2018

Scientists identify special pair of RNA scissors with many functions

CRISPR/Cas systems are known as promising "gene scissors" in the genome editing of plants, animals, and microorganisms by targeting specific regions in their DNA - and perhaps they can even be used to correct genetic defects.

8 Feb 2018

Myriad’s myRisk Hereditary Cancer test finds inherited gene mutations in more than 12% of prostate cancer patients

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, announced today that results from a large 1,162 patient study of the Myriad myRisk Hereditary Cancer test will be featured during the poster presentation at the 2018 Genitourinary Cancer Symposium in San Francisco, Calif.

8 Feb 2018

Positivity keeps dementia at bay finds study

Persons who have developed positive attitudes towards life and aging are less likely to develop dementia finds a new study. Becca Levy from the Yale School of Public Health, USA, and colleagues have published the reports of this encouraging study in the latest issue of the journal PLOS ONE.

8 Feb 2018

Researchers identify presence of ER gene fusion proteins in treatment-resistant breast cancer

At Magee-Womens Research Institute and UPMC Hillman Cancer Center, a large team of clinical and laboratory researchers dedicated to understanding treatment resistance in the most common form of breast cancer have identified a new genetic change in the estrogen receptor that contributes to therapy resistance.

7 Feb 2018

Novel genetic mutations may explain link between high HDL cholesterol and reduced heart disease risk

Researchers at the University of Maryland School of Medicine have uncovered genetic mutations that may explain why people with high levels of high-density lipoprotein (HDL) cholesterol, the "good cholesterol," have a reduced risk of coronary heart disease.

7 Feb 2018

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

A research team led by a biochemist at the University of California, Riverside has solved the crystal structure for an enzyme that plays a key role in DNA methylation, the process by which methyl groups are added to the DNA molecule.

7 Feb 2018

Novel technology platform for custom designing bacteriophages

Bacteriophages, known informally as phages, are viruses that can attack and kill specific bacteria. They occur everywhere in the natural world. Precisely because they are matched to just one specific type of bacteria, researchers and medics hope that phages can be engineered to combat certain bacterial infections.

7 Feb 2018

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Scientists have for the first time discovered a mechanism that limits the number of "cellular janitors" in the nervous system, leading to increased risk for two neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal dementia, according to a Keck School of Medicine of USC study published today in Nature Medicine.

7 Feb 2018

Study adds more evidence that intestinal microbiome plays substantial role in obesity

A new Johns Hopkins study of mice with the rodent equivalent of metabolic syndrome has added to evidence that the intestinal microbiome - a "garden" of bacterial, viral and fungal genes - plays a substantial role in the development of obesity and insulin resistance in mammals, including humans.

6 Feb 2018

UIC scientists identify new chemical compound to stop bacteria from causing sickness

A study published in the Journal of Biological Chemistry is the first to describe a signaling pathway that affects communication -- a process called quorum sensing -- between Streptococcus bacteria cells.

6 Feb 2018

New CRISPR gene-editing technique can correct majority of mutations that cause DMD

Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of the 3,000 mutations that cause Duchenne muscular dystrophy (DMD) by making a single cut at strategic points along the patient's DNA, according to a study from UT Southwestern Medical Center.

6 Feb 2018

Scientists develop new system to match genetic anomalies with precision medicine treatments

A team of computer scientists from the University of Delaware and Georgetown University has developed a new system to rapidly determine which cancer drugs are likely to work best given a patient's genetic markers.

6 Feb 2018

Next-generation ‘active genetics’ tool opens new horizons

In 2015, University of California San Diego biologists Ethan Bier and Valentino Gantz developed a breakthrough technology known as "active genetics," which results in parents transmitting a genetic trait to most of their offspring (instead of 50 percent receiving the trait under standard inheritance).

6 Feb 2018

Detailed phenotypic information on resistance genes can guide future drug development

The genes that are able to equip bacteria with resistance to clinically used antibiotics have been found in many different natural environments. Nevertheless, a functional overview of the resistance genes found in common human bacterial pathogens has been missing so far.

6 Feb 2018

Researchers identify potential 'first-line' treatment for rare bone loss disease

A possible 'first-line' treatment for a rare bone loss disease has been identified by a research team led by Tohoku University in Japan. The research findings, published in the journal Molecular Cell, could also provide insight into treating age-related osteoporosis.

6 Feb 2018

Researchers report technical advances in production of HIV vaccines

Research on HIV over the past decade has led to many promising ideas for vaccines to prevent infection by the AIDS virus, but very few candidate vaccines have been tested in clinical trials.

6 Feb 2018

Researchers uncover novel therapeutic target for type 2 diabetes

Researchers from Kanazawa University and the National Center for Global Health and Medicine in Tokyo report, in Nature Communications, a new mechanism for regulating glucose uptake by the liver which has implications for type 2 diabetes and its treatment.

6 Feb 2018

Gene News and Research

Latest Gene News and Research

Human iPS cell-derived inner ear cells may improve hereditary hearing loss

Special protein improves survival and lung function of mice with influenza, study shows

International research collaboration finds genetic mutation linked to Crohn's disease

Scientists identify special pair of RNA scissors with many functions

Myriad’s myRisk Hereditary Cancer test finds inherited gene mutations in more than 12% of prostate cancer patients

Positivity keeps dementia at bay finds study

Researchers identify presence of ER gene fusion proteins in treatment-resistant breast cancer

Novel genetic mutations may explain link between high HDL cholesterol and reduced heart disease risk

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

Novel technology platform for custom designing bacteriophages

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Study adds more evidence that intestinal microbiome plays substantial role in obesity

UIC scientists identify new chemical compound to stop bacteria from causing sickness

New CRISPR gene-editing technique can correct majority of mutations that cause DMD

Scientists develop new system to match genetic anomalies with precision medicine treatments

Next-generation ‘active genetics’ tool opens new horizons

Detailed phenotypic information on resistance genes can guide future drug development

Researchers identify potential 'first-line' treatment for rare bone loss disease

Researchers report technical advances in production of HIV vaccines

Researchers uncover novel therapeutic target for type 2 diabetes

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research