Gene News and Research

Latest Gene News and Research

Defect in DNA repair machinery causes underdevelopment of neural network

DNA is the computer code that programs every event in the body. Despite the importance of DNA fidelity, as the body develops, cells grow and replicate, DNA is constantly turned over. This repeated process can compromise the DNA, which is why the body has many DNA repair machineries.

30 Aug 2017

Stabilizing TREM2 could be viable therapeutic strategy to combat Alzheimer's disease

A gene called triggering receptor expressed on myeloid cells 2, or TREM2, has been associated with numerous neurodegenerative diseases, such as Alzheimer's disease, Frontotemporal lobar degeneration, Parkinson's disease, and Nasu-Hakola disease. Recently, a rare mutation in the gene has been shown to increase the risk for developing Alzheimer's disease.

30 Aug 2017

Study sheds new light on gene fusion in bladder and brain cancer

A study by the University of Warwick sheds new light on gene fusion in bladder and brain cancer.

30 Aug 2017

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Scientists at Children's Hospital of Philadelphia report that a drug candidate that blocks abnormal protein signals may lead to the first pharmacologic treatment for hereditary multiple exostoses (HME), a rare pediatric genetic disease.

29 Aug 2017

Immunotherapy that uses existing cancer drugs in a new way delivers promising results

Immunotherapy is an emerging field in the global fight against cancer, even though scientists and clinicians have been working for decades to find ways to help the body's immune system detect and attack cancerous cells.

29 Aug 2017

Pathway from ADI to AUD symptoms influenced by ethnicity and genetics

Studies have shown that an early age of drinking initiation (ADI) increases the chance of developing an alcohol use disorder (AUD).

29 Aug 2017

SBP scientist receives DoD award to identify new and efficacious treatments for pancreatic cancer

Sanford Burnham Prebys Medical Discovery Institute is pleased to announce that the Department of Defense (DoD) has awarded Cosimo Commisso, Ph.D., a Career Development Award to identify new and efficacious treatments for pancreatic cancer.

29 Aug 2017

Research reveals LEGO-like stacking of protein complexes

When hemoglobin undergoes just one mutation, the protein complexes stick to one another, stacking like LEGO blocks to form long, stiff filaments.

29 Aug 2017

Research findings potentially open door to new treatments for eye trauma and retinal disease

Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye's circuitry, new research shows. The findings potentially open the door to new treatments for eye trauma and retinal disease.

28 Aug 2017

Biomedical engineering researchers aim to attack two banes of cardiovascular disease

Biomedical engineering researchers will attack two banes of cardiovascular disease - heart failure after heart attacks and the scourge of resistant high blood pressure - with $4.8 million in National Institutes of Health grants that begin this fall.

26 Aug 2017

Junk genes could one day offer framework for treating people with familial hypercholesterolemia

Scientists from UCLA and the Howard Hughes Medical Institute successfully used a gene that suppresses cholesterol levels as part of a treatment to reduce plaque in mice with a disorder called familial hypercholesterolemia.

26 Aug 2017

High levels of microbes deprive host of essential nutrients, research suggests

"Gut bacteria get to use a lot of our food before we do," says Federico Rey, a professor of bacteriology at the University of Wisconsin-Madison. Then we get their leftovers -- or their waste.

26 Aug 2017

New drug shows promising results for treating spinal muscular atrophy

A drug developed by an Iowa State University biomedical researcher as a potential treatment for spinal muscular atrophy showed promising results in a recently published study.

26 Aug 2017

Yale experts uncover genes associated with immune response to flu vaccination

Yale experts and their partners in a national research consortium have identified several genes and gene clusters associated with the immune response to flu vaccination.

26 Aug 2017

Scientists develop new system to identify and characterize regulatory DNA sequences

Scientists from the Children's Medical Center Research Institute at UT Southwestern have developed an innovative system to identify and characterize the molecular components that control the activities of regulatory DNA sequences in the human genome.

24 Aug 2017

Manipulation of single gene defines new pathway to mood disorders

Removing a single gene from the brains of mice and zebrafish causes these animals to become more anxious than normal.

24 Aug 2017

Increased enzyme production by the liver causes fatty liver, obesity and insulin resistance

In mice that are given a high-fat diet, an increased production of the enzyme DPP4 by the liver promotes an increase in body fat, the development of fatty liver disease and insulin resistance.

24 Aug 2017

Long non-coding RNAs could represent novel male infertility drug targets

Scientists have found distinctive portions of genetic material--known as lncRNAs--that help sperm develop. Male mice lacking a particular lncRNA have low sperm count, suggesting lncRNAs could represent novel infertility drug targets.

24 Aug 2017

Study provides better understanding of how estrogen regulates gene expression

Estrogen hormones regulate gene expression. They achieve this by first binding to estrogen receptor in the cell nucleus, which triggers the recruitment of different molecules called coactivators in specific order.

24 Aug 2017

Acid-sensing receptor may have significant relevance to physiological response in panic disorder

Panic disorder is a syndrome characterized by spontaneous and recurrent episodes of incapacitating anxiety. It typically emerges during adolescence or early adulthood and can take an exhausting emotional and physical toll on the body.

24 Aug 2017

Gene News and Research

Latest Gene News and Research

Defect in DNA repair machinery causes underdevelopment of neural network

Stabilizing TREM2 could be viable therapeutic strategy to combat Alzheimer's disease

Study sheds new light on gene fusion in bladder and brain cancer

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Immunotherapy that uses existing cancer drugs in a new way delivers promising results

Pathway from ADI to AUD symptoms influenced by ethnicity and genetics

SBP scientist receives DoD award to identify new and efficacious treatments for pancreatic cancer

Research reveals LEGO-like stacking of protein complexes

Research findings potentially open door to new treatments for eye trauma and retinal disease

Biomedical engineering researchers aim to attack two banes of cardiovascular disease

Junk genes could one day offer framework for treating people with familial hypercholesterolemia

High levels of microbes deprive host of essential nutrients, research suggests

New drug shows promising results for treating spinal muscular atrophy

Yale experts uncover genes associated with immune response to flu vaccination

Scientists develop new system to identify and characterize regulatory DNA sequences

Manipulation of single gene defines new pathway to mood disorders

Increased enzyme production by the liver causes fatty liver, obesity and insulin resistance

Long non-coding RNAs could represent novel male infertility drug targets

Study provides better understanding of how estrogen regulates gene expression

Acid-sensing receptor may have significant relevance to physiological response in panic disorder

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging