Gene News and Research

Latest Gene News and Research

Researchers identify new antibiotic resistance gene in bacteria from dairy cows

Researchers of the University of Bern have identified a new antibiotic resistance gene in bacteria from dairy cows. This gene confers resistance to all beta-lactam antibiotics including the last generation of cephalosporins used against methicillin-resistant Staphylococcus aureus.

26 Apr 2017

Removing senescent cells from joints could reverse progression of osteoarthritis

In a preclinical study in mice and human cells, researchers report that selectively removing old or 'senescent' cells from joints could stop and even reverse the progression of osteoarthritis.

26 Apr 2017

Obesity amplifies effects of three risk alleles linked to NAFLD

An international study based at UT Southwestern Medical Center revealed a striking genetic-environmental interaction: Obesity significantly amplifies the effects of three gene variants that increase risk of nonalcoholic fatty liver disease by different metabolic pathways.

26 Apr 2017

Study provides new insights on molecular mechanisms that impair muscle stem cells during aging

Researchers at Sanford Burnham Prebys Medical Discovery Institute have identified a previously unrecognized step in stem cell-mediated muscle regeneration.

26 Apr 2017

Studies uncover link between immune system, brain structure and memory

The body's immune system performs essential functions, such as defending against bacteria and cancer cells. However, the human brain is separated from immune cells in the bloodstream by the so-called blood-brain barrier.

26 Apr 2017

New field laboratory-deployed molecular test could eliminate malaria

As the global community gathers for World Malaria Day to celebrate successes and plot strategy to eliminate the disease from the face of the earth, a new ray of hope is emerging from a surprising place: the testing side of the equation.

26 Apr 2017

Epigenetic changes detectable at birth linked to risk of obesity

These changes, known as epigenetic modifications, control the activity of our genes without changing the actual DNA sequence. One of the main epigenetic modifications is DNA methylation, which plays a key role in embryonic development and the formation of different cell types, regulating when and where genes are switched on.

26 Apr 2017

Scientists use modern techniques to investigate how silver poisons pathogenic microbes

Silver and other metals have been used to fight infections since ancient times. Today, researchers are using sophisticated techniques such as the gene-editing platform Crispr-Cas9 to take a closer look at precisely how silver poisons pathogenic microbes - and when it fails.

26 Apr 2017

Vitamin A combined with high-fat diet may lead to increased risk for obesity and diabetes

Vitamin A is an essential nutrient that the human body needs to function properly. But new research presented today at the American Physiological Society annual meeting at Experimental Biology 2017 in Chicago suggests that normal levels of vitamin A within a high-fat diet can negatively affect expression of liver genes associated with glucose and fat metabolism.

26 Apr 2017

Researchers discover genes linked to resilience against brain pathologies

The pathologies (damage) in the brain that stroke, Alzheimer's disease and other neurological conditions cause in older adults only partially explain the memory loss, reduced reasoning ability and other cognitive impairments that result from these conditions. Little is known about why the effects of brain pathology vary between people who develop it.

26 Apr 2017

Changes in estrogen can trigger atypical functioning in memory circuit of women with gene variant

Fluctuations in estrogen can trigger atypical functioning in a key brain memory circuit in women with a common version of a gene, NIMH scientists have discovered.

25 Apr 2017

Study provides new understanding of molecular mechanisms that impact intellectual disability

Scientists from the Florida campus of The Scripps Research Institute have shown that a protein helps balance nerve cell communication.

25 Apr 2017

Researchers identify new rare genetic variants linked to extreme longevity

The search for the genetic determinants of extreme longevity has been challenging, with the prevalence of centenarians (people older than 100) just one per 5,000 population in developed nations.

25 Apr 2017

Research shows how TET2 protein loss can open door for mutations that drive blood cancers

Imagine this scenario on a highway: A driver starts to make a sudden lane change but realizes his mistake and quickly veers back, too late. Other motorists have already reacted and, in some cases, collide. Meanwhile, the original motorist - the one who caused the problem - drives on.

25 Apr 2017

Scientists create new technique for studying how chlamydia interacts with immune system

Scientists at the Wellcome Trust Sanger Institute and their collaborators at the University of British Columbia have created an innovative technique for studying how chlamydia interacts with the human immune system.

25 Apr 2017

Low levels of NPTX2 protein in the brain may lead to learning and memory loss in Alzheimer's disease

Working with human brain tissue samples and genetically engineered mice, Johns Hopkins Medicine researchers together with colleagues at the National Institutes of Health, the University of California San Diego Shiley-Marcos Alzheimer's Disease Research Center, Columbia University, and the Institute for Basic Research in Staten Island say that consequences of low levels of the protein NPTX2 in the brains of people with Alzheimer's disease (AD) may change the pattern of neural activity in ways that lead to the learning and memory loss that are hallmarks of the disease.

25 Apr 2017

Orange essential oil may offer non-pharmaceutical option to help improve PTSD

About 8 percent of people will develop post-traumatic stress disorder at some point in their lives, according to the U.S. Department of Veterans Affairs, yet treatments for this debilitating condition remain limited.

25 Apr 2017

Scientists use stem cells to identify underlying cellular defects that cause Angelman syndrome

Researchers at UConn Health used stem cells derived from patients with Angelman syndrome to identify the underlying cellular defects that cause the rare neurogenetic disorder, an important step in the ongoing search for potential treatments for Angelman and a possible cure.

25 Apr 2017

Whole-exome sequencing may routinely miss detecting some disease-causing genes, say researchers

Whole-exome DNA sequencing -- a technology that saves time and money by sequencing only protein-coding regions and not the entire genome -- may routinely miss detecting some genetic variations associated with disease, according to Penn State researchers who have developed new ways to identify such omissions.

24 Apr 2017

Researchers discover gene that may play role in restoring hearing after noise exposure

Researchers have discovered that a protein implicated in human longevity may also play a role in restoring hearing after noise exposure. The findings, where were published in the journal Scientific Reports, could one day provide researchers with new tools to prevent hearing loss.

24 Apr 2017

Gene News and Research

Latest Gene News and Research

Researchers identify new antibiotic resistance gene in bacteria from dairy cows

Removing senescent cells from joints could reverse progression of osteoarthritis

Obesity amplifies effects of three risk alleles linked to NAFLD

Study provides new insights on molecular mechanisms that impair muscle stem cells during aging

Studies uncover link between immune system, brain structure and memory

New field laboratory-deployed molecular test could eliminate malaria

Epigenetic changes detectable at birth linked to risk of obesity

Scientists use modern techniques to investigate how silver poisons pathogenic microbes

Vitamin A combined with high-fat diet may lead to increased risk for obesity and diabetes

Researchers discover genes linked to resilience against brain pathologies

Changes in estrogen can trigger atypical functioning in memory circuit of women with gene variant

Study provides new understanding of molecular mechanisms that impact intellectual disability

Researchers identify new rare genetic variants linked to extreme longevity

Research shows how TET2 protein loss can open door for mutations that drive blood cancers

Scientists create new technique for studying how chlamydia interacts with immune system

Low levels of NPTX2 protein in the brain may lead to learning and memory loss in Alzheimer's disease

Orange essential oil may offer non-pharmaceutical option to help improve PTSD

Scientists use stem cells to identify underlying cellular defects that cause Angelman syndrome

Whole-exome sequencing may routinely miss detecting some disease-causing genes, say researchers

Researchers discover gene that may play role in restoring hearing after noise exposure

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