Gene News and Research

Latest Gene News and Research

Targeted lung cancer treatments may benefit smokers and non-smokers alike

Smokers are less likely than non-smokers to have lung cancers caused by targetable genetic changes. But a study published this week in the journal Clinical Cancer Research shows that when they do, smokers benefit just as much as non-smokers from targeted treatments.

13 Dec 2017

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

A new study shows that attaching antibody-like RNA nanoparticles to microvesicles can deliver effective RNA therapeutics such as small interfering RNA specifically to cancer cells.

13 Dec 2017

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Inflammatory bowel disease (IBD), including the two conditions ulcerative colitis and Crohn's disease, results in long-term inflammation of the gut and is associated with dysregulation of the immune system.

13 Dec 2017

Scientists develop new, high resolution method for identifying microbial species and strains

Scientists from the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions New York University and the University of Florida today published a report detailing their new, more accurate method for identifying individual microbial species and strains in a community.

13 Dec 2017

New study explains why one identical twin more at risk for autoimmune diseases

It does not matter if you raise them the same, feed them the same, or dress them the same, any parent with identical twins knows their two children are remarkably different. Identical twins are identical in genes, but they are not identical in gene expressions, a difference due to epigenetics.

12 Dec 2017

Study reveals how the body clock and time of day may influence autoimmune conditions

Insights into how the body clock and time of day influence immune responses are revealed today in a study published in leading international journal Nature Communications.

12 Dec 2017

Researchers reveal pathological mechanisms in congenital myotonic dystrophy

Myotonic dystrophy (DM) is the most common form of genetic muscular dystrophy that begins in adulthood. DM is characterized by progressive muscle wasting and weakness. People with this disorder often have prolonged muscle contractions (myotonic) and are not able to relax certain muscles after use.

12 Dec 2017

New scientific yardstick released to help early detection of Alzheimer's disease

The European Commission's Joint Research Centre released a new scientific yardstick, in the form of a certified reference material, to help early detection of Alzheimer's disease.

12 Dec 2017

Myriad Genetics announces new data on EndoPredict test at 2017 San Antonio Breast Cancer Symposium

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced new results from two studies with EndoPredict are being featured at the 2017 San Antonio Breast Cancer Symposium in San Antonio, Texas.

12 Dec 2017

Researchers identify promising solution for improving cystic fibrosis treatments

Researchers at the University of Montreal Hospital Research Centre have identified a promising solution to improving treatments offered to patients with cystic fibrosis.

12 Dec 2017

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

Huntington's disease is a neurodegenerative disease. It is always fatal. The disease is caused by a defect in the Huntingtin gene. To this day, no therapy will put a stop to the insidious disintegration of brain cells.

12 Dec 2017

Researchers find new role for SHARPIN protein in melanoma growth

Researchers at Sanford Burnham Prebys Medical Discovery and the Technion in Israel have found a new role for the SHARPIN protein. In addition to being one of three proteins in the linear ubiquitin chain assembly complex, regulating NFκB and other inflammatory molecules, SHARPIN modulates PRMT5, an epigenetic master switch that controls several proteins linked to melanoma. The research was published in The Journal of Clinical Investigation.

12 Dec 2017

Huntington's disease drug clears initial hurdles - raising hopes

Huntington’s disease is a genetic disorder that affects the brain progressively and has no known cure till date. In a breakthrough, the first drug that can target and reduce the cause behind this dreaded disease has been found to be effective, safe and well tolerated in a human clinical trial that was conducted by UCL scientists.

11 Dec 2017

Study: Combination targeted therapy has high response rates in AML patients

Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up to 50 percent patients say researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2017

Study provides new insights into mechanism of tumor survival in glioblastoma

A Northwestern Medicine study, published in the journal Cancer Cell, has provided new insights into a mechanism of tumor survival in glioblastoma and demonstrated that inhibiting the process could enhance the effects of radiation therapy.

11 Dec 2017

Butler Hospital launches international Alzheimer's disease prevention study

The Memory and Aging Program at Butler Hospital, a member of Care New England and a major teaching affiliate of The Warren Alpert Medical School of Brown University, enrolled one of the initial participants in an international Alzheimer's disease (AD) prevention study.

11 Dec 2017

Researchers discover potential regulator essential for killer T cells to reside in tumors

Researchers report the discovery that a protein called "Runx3" programs killer T cells to establish residence in tumors and infection sites.

11 Dec 2017

New, more easily administered therapies offer benefits for bleeding and clotting disorders

In three studies being presented today during the 59th American Society of Hematology (ASH) Annual Meeting and Exposition in Atlanta, researchers report remarkable benefits from new, more easily administered therapies for bleeding and clotting disorders.

11 Dec 2017

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Among younger patients newly diagnosed with chronic lymphocytic leukemia (CLL), treatment with a combination of chemotherapy and a molecularly targeted drug significantly improves response over what is typically seen with chemotherapy alone, according to an investigator-initiated multi-center phase II clinical trial.

11 Dec 2017

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Early evidence suggests that gene therapy developed at St. Jude Children's Research Hospital will lead to broad protection for infants with the devastating immune disorder X-linked severe combined immunodeficiency disorder.

11 Dec 2017

Gene News and Research

Latest Gene News and Research

Targeted lung cancer treatments may benefit smokers and non-smokers alike

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Scientists develop new, high resolution method for identifying microbial species and strains

New study explains why one identical twin more at risk for autoimmune diseases

Study reveals how the body clock and time of day may influence autoimmune conditions

Researchers reveal pathological mechanisms in congenital myotonic dystrophy

New scientific yardstick released to help early detection of Alzheimer's disease

Myriad Genetics announces new data on EndoPredict test at 2017 San Antonio Breast Cancer Symposium

Researchers identify promising solution for improving cystic fibrosis treatments

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

Researchers find new role for SHARPIN protein in melanoma growth

Huntington's disease drug clears initial hurdles - raising hopes

Study: Combination targeted therapy has high response rates in AML patients

Study provides new insights into mechanism of tumor survival in glioblastoma

Butler Hospital launches international Alzheimer's disease prevention study

Researchers discover potential regulator essential for killer T cells to reside in tumors

New, more easily administered therapies offer benefits for bleeding and clotting disorders

Combination of chemotherapy and targeted drug improves response in younger CLL patients

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)