Gene News and Research

Latest Gene News and Research

Study paves way for new therapeutic strategies to impede growth of virus-induced cancers

Researchers at the Cancer Science Institute of Singapore at the National University of Singapore have identified a novel molecular pathway by which a tumor suppressor, TIP60, inhibits the growth of cancer cells.

7 Dec 2017

Researchers establish function of long RNA strands in skin development and disease

Researchers have found out how long pieces of RNA called “long non-coding RNAs” (LncRNAs) work in skin cells to modulate connective tissue proteins such as collagen, potentially laying the foundations for new skin repair therapies.

7 Dec 2017

UA researcher awarded $2.3 million NIH grant to develop new treatments for depression

A University of Arizona College of Medicine-Phoenix researcher has received a $2.3 million grant from the National Institutes of Health to develop new treatments for depression.

7 Dec 2017

Brazilian researchers identify genes linked to melanoma progression

When researchers at the University of São Paulo in Brazil treated human melanoma cell lines with a synthetic compound similar to curcumin, one of the pigments that give turmeric its orange color, they identified genes with altered expression in potentially invasive tumors and malignant cells resistant to chemotherapy.

6 Dec 2017

CLOCK gene plays key role in regulating many genes important to brain evolution

Scientists have long sought to unravel the molecular mysteries that make the human brain special: What processes drove its evolution through the millennia? Which genes are critical to cognitive development?

6 Dec 2017

Clinical study uses genetic testing to match AML patients with new therapies

A clinical trial using genetic testing to match acute myeloid leukemia (AML) patients with new therapies is now open at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center

6 Dec 2017

New compound targets APOE gene to reduce Alzheimer's damage in mice

People who carry the APOE4 genetic variant face a substantial risk for developing Alzheimer's disease.

6 Dec 2017

Study shows how interplay between two key enzymes promotes brain tumor growth

Study results revealed previously unknown interplay between two key enzymes and a novel understanding of how brain cancer tumors form and spread, according to researchers at The University of Texas MD Anderson Cancer Center.

6 Dec 2017

Bacteria carrying colistin resistant mcr-1 gene commonly exist in ecosystem, study finds

Food Safety and Technology Research Centre of the Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University recently found that bacteria that carry the colistin resistance gene mcr-1 commonly exist in human and various types of food and environmental samples collected from Hong Kong and the Chinese mainland.

6 Dec 2017

Researchers identify risk factor for drug-induced skin disease in diabetic patients

Researchers have identified a type of human leukocyte antigen (HLA) that is associated with the skin disease bullous pemphigoid (BP) in diabetic patients administered with DPP-4 inhibitory drugs.

6 Dec 2017

High ADAR1 enzyme levels correlate with reduced survival rates in multiple myeloma

Multiple myeloma is the second most common blood cancer in the United States. Thirty to 50 percent of multiple myeloma patients have extra copies of the gene that encodes the enzyme ADAR1.

6 Dec 2017

Harvard scientists discover hundreds of genetic switches that influence height

It's been understood for decades that a host of factors - everything from pre- and post-natal health, nutrition, and genetics - play a role in determining height, but efforts to untangle the complex web of factors that contribute to height have long been stymied.

6 Dec 2017

Reducing mitochondrial protein in cardiac muscle cells initiates heart failure

Reducing a protein found in the mitochondria of cardiac muscle cells initiates cardiac dysfunction and heart failure, a finding that could provide insight for new treatments for cardiovascular diseases, a study led by Georgia State University has shown.

6 Dec 2017

Specific protein negatively affects pancreatic cells and leads to cancer growth

Pancreatic cancer is one of the most aggressive forms of cancer and is currently very difficult to treat. However, the last few years have seen advances in the scientific understanding of how this cancer develops at a molecular level.

6 Dec 2017

Immune-boosting drug combination may hold promise for treating ovarian cancer

Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor burden and significantly longer survival than those that received any of the drugs alone.

5 Dec 2017

New study examines effects of gene variant on resting-state brain function in patients with MDD

A new study assessed the effects of a SLC6A15 gene variant on resting-state brain function in patients with major depressive disorder (MDD), comparing the results with those in healthy individuals.

5 Dec 2017

Study uncovers genes that drive peanut allergy reactions

Mount Sinai researchers have identified six genes that activate hundreds of other genes in children experiencing severe allergic reactions to peanuts.

5 Dec 2017

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

The investigational Zika purified inactivated virus (ZPIV) vaccine was well-tolerated and induced an immune response in participants, according to initial results from three Phase 1 clinical trials.

5 Dec 2017

DNA sequencing could identify genetic cause of kidney disease

DNA sequencing could soon become part of the routine diagnostic workup for patients with chronic kidney disease, suggests a new study from Columbia University Medical Center.

5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Gene News and Research

Latest Gene News and Research

Study paves way for new therapeutic strategies to impede growth of virus-induced cancers

Researchers establish function of long RNA strands in skin development and disease

UA researcher awarded $2.3 million NIH grant to develop new treatments for depression

Brazilian researchers identify genes linked to melanoma progression

CLOCK gene plays key role in regulating many genes important to brain evolution

Clinical study uses genetic testing to match AML patients with new therapies

New compound targets APOE gene to reduce Alzheimer's damage in mice

Study shows how interplay between two key enzymes promotes brain tumor growth

Bacteria carrying colistin resistant mcr-1 gene commonly exist in ecosystem, study finds

Researchers identify risk factor for drug-induced skin disease in diabetic patients

High ADAR1 enzyme levels correlate with reduced survival rates in multiple myeloma

Harvard scientists discover hundreds of genetic switches that influence height

Reducing mitochondrial protein in cardiac muscle cells initiates heart failure

Specific protein negatively affects pancreatic cells and leads to cancer growth

Immune-boosting drug combination may hold promise for treating ovarian cancer

New study examines effects of gene variant on resting-state brain function in patients with MDD

Study uncovers genes that drive peanut allergy reactions

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

DNA sequencing could identify genetic cause of kidney disease

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

eBook: Using iPSCs models for human disease research and drug discovery eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)