Gene News and Research

Latest Gene News and Research

Genetic variant encoded in NCF1 linked to increased risk for autoimmune diseases, study shows

Investigators at the Medical University of South Carolina report pre-clinical research showing that a genetic variant encoded in neutrophil cystolic factor 1 (NCF1) is associated with increased risk for autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and Sjögren's syndrome, in the January 2017 issue of Nature Genetics.

8 Feb 2017

Geneticists use evolutionary history to shine light on plethora of neurodevelopmental disorders

Geneticists from Trinity College Dublin have used our evolutionary history to shine light on a plethora of neurodevelopmental disorders and diseases.

8 Feb 2017

Study sheds light on role of brain region in social behavior and pathology in autism

Researchers at Rosalind Franklin University of Medicine and Science have induced empathy-like behavior by identifying then manipulating a brain circuit in an experimental model, an indication that new strategies may help people with autism spectrum disorder gain social abilities.

8 Feb 2017

Researchers discover function of olfactory receptors in human heart muscle

Researchers have for the first time identified the function of olfactory receptors in the human heart muscle, such as are also present in the nose. One of the receptors reacts to fatty acids that occur in the blood, in patients with diabetes significantly above the normal range.

8 Feb 2017

Study sheds light on role of Armc5 protein in foetal development and T-cell immune responses

Genetic mutations of the Armc5 gene disrupt foetal development and compromise the immune response.

8 Feb 2017

UNC scientists confirm and clarify key molecular details of nucleotide excision repair

Day in and day out, in our bodies, the DNA in cells is damaged for a variety of reasons, and thus intercellular DNA-repair systems are fundamental to the maintenance of life.

8 Feb 2017

Novel cell therapy may repair heart damage using modified cells from facial muscle

Researchers at the University of Cincinnati have received $2.4 million in federal funding to pursue research on a novel cell therapy that would repair heart damage using modified cells taken from the patient's own facial muscle.

8 Feb 2017

New study uncovers important links between glioblastoma and epileptic seizures

Detecting brain tumors at the earliest possible stage and eliminating them before seizures begin might be possible one day, according to research by scientists at Baylor College of Medicine and Texas Children's Hospital.

7 Feb 2017

Mutated genes lead to tooth enamel defects that increase risk of caries

Bacteria are not the sole cause of caries; tooth resistance also plays an instrumental role. Researchers from the University of Zurich demonstrate that mutated genes lead to defects in the tooth enamel and can therefore encourage the development of caries.

7 Feb 2017

Melanoma research breakthrough opens up new pathways to treatment

A QUT-driven project has identified the way in which melanoma cells spread, opening up new pathways to treatment via drugs to 'turn off' the invasive gene.

7 Feb 2017

Researchers create first animal model of rare disease linked to problem of adrenal glands

The name of the gene is Armc5, for Armadillo repeat containing 5. Until now, its function was unknown. After 10 years of research, a team at the University of Montreal Hospital Research Centrehas succeeded in deleting this gene in experimental mice and discovered that its loss gives rise to a heretofore unidentified syndrome.

7 Feb 2017

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

One of the most promising areas of cancer research is personalized therapy using precision medicine. The National Cancer Institute's NCI-MATCH is a large, ongoing clinical trial that matches tumors to therapies based on the tumor's genetic characteristics.

7 Feb 2017

Scientists find new method for identifying therapeutic targets in cancers lacking tumor suppressor genes

A new method has been found for identifying therapeutic targets in cancers lacking specific key tumor suppressor genes.

7 Feb 2017

Uterine glands produce several key factors for embryo growth and pregnancies, study shows

The majority of pregnancy losses occur during the first trimester, when biological communication between the embryo and mother is critical for the establishment of the pregnancy.

7 Feb 2017

Scientists show how immune receptor activated by bacteria contributes to diabetic bladder dysfunction

Bladder dysfunction is a reality for about half of patients with diabetes and now scientists have evidence that an immune system receptor that's more typically activated by bacteria is a major contributor.

7 Feb 2017

Study could provide novel therapeutic approach for preventing severe jaundice in newborn babies

For many newborn babies, an enzyme that breaks down the molecule bilirubin doesn't activate right away. The resulting bilirubin buildup can lead to jaundice, a typically harmless condition that causes a baby's skin to temporarily appear yellow.

6 Feb 2017

Northwestern Medicine scientists discover retinal cell that may cause myopia

Northwestern Medicine scientists have discovered a cell in the retina that may cause myopia when it dysfunctions. The dysfunction may be linked to the amount of time a child spends indoors and away from natural light.

6 Feb 2017

Scientists evaluate rapid test that detects colistin resistance gene in bacterial isolates

Colistin is used as the "last-resort antibiotic" for dreaded multidrug-resistant pathogens, especially in hospitals. However, gut bacteria that have become insensitive to colistin now exist -- owing to the mobile resistance gene mcr-1. In early 2016, bacteria carrying this resistance gene were detected in Germany for the first time.

6 Feb 2017

Researchers evaluate biological effects of exposure to cigarette smoke versus e-cigarette aerosols

Researchers reported changes in the expression levels of 123 genes when reconstituted lung tissue was exposed to cigarette smoke, compared to only two genes that could be confirmed following exposure to e-cigarette aerosols.

6 Feb 2017

PERK protein could be target for development of new drugs for progressive supranuclear palsy

The brain disease "progressive supranuclear palsy" (PSP) is currently incurable and its symptoms can only be eased to a very limited degree. PSP impairs eye movements, locomotion, balance control, and speech.

6 Feb 2017

Gene News and Research

Latest Gene News and Research

Genetic variant encoded in NCF1 linked to increased risk for autoimmune diseases, study shows

Geneticists use evolutionary history to shine light on plethora of neurodevelopmental disorders

Study sheds light on role of brain region in social behavior and pathology in autism

Researchers discover function of olfactory receptors in human heart muscle

Study sheds light on role of Armc5 protein in foetal development and T-cell immune responses

UNC scientists confirm and clarify key molecular details of nucleotide excision repair

Novel cell therapy may repair heart damage using modified cells from facial muscle

New study uncovers important links between glioblastoma and epileptic seizures

Mutated genes lead to tooth enamel defects that increase risk of caries

Melanoma research breakthrough opens up new pathways to treatment

Researchers create first animal model of rare disease linked to problem of adrenal glands

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

Scientists find new method for identifying therapeutic targets in cancers lacking tumor suppressor genes

Uterine glands produce several key factors for embryo growth and pregnancies, study shows

Scientists show how immune receptor activated by bacteria contributes to diabetic bladder dysfunction

Study could provide novel therapeutic approach for preventing severe jaundice in newborn babies

Northwestern Medicine scientists discover retinal cell that may cause myopia

Scientists evaluate rapid test that detects colistin resistance gene in bacterial isolates

Researchers evaluate biological effects of exposure to cigarette smoke versus e-cigarette aerosols

PERK protein could be target for development of new drugs for progressive supranuclear palsy

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