Gene News and Research

Latest Gene News and Research

UT Southwestern scientists unravel role of PARP enzymes in major cellular activities

A component of an enzyme family linked to DNA repair, stress responses, and cancer also plays a role in enhancing or inhibiting major cellular activities under physiological conditions, new research shows.

16 Feb 2017

Discovery of 'molecular switch' could lead to effective new treatments for auto-immune diseases

The discovery of the 'molecular switch' that causes inflammatory bowel disease (IBD) and Celiac disease, could lead to more effective new treatments for these life-changing auto-immune conditions, according to research from scientists at King's College London and University College London.

16 Feb 2017

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

The Helmholtz Zentrum München has published results of the largest genome-wide association study on proteomics to date.

16 Feb 2017

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

Genomic testing of biopsies from patients with deadly, treatment-resistant cancerous blood syndromes called histiocytoses allowed doctors to identify genes fueling the ailments and use targeted molecular drugs to successfully treat them.

16 Feb 2017

HMS scientists listen to crosstalk between gut microbes and immune system

The human gut is home to some 100 trillion bacteria, comprising between 250 and 500 species. This astounding array of organisms, collectively known as the gut microbiome, is a powerful regulator of disease and health and has been implicated in conditions ranging from inflammatory bowel disease to multiple sclerosis.

16 Feb 2017

Glowing mice could mark major step forward for new gene therapy

Timothy Blake, a postdoctoral fellow in the Waymouth lab, was hard at work on a fantastical interdisciplinary experiment. He and his fellow researchers were refining compounds that would carry instructions for assembling the protein that makes fireflies light up and deliver them into the cells of an anesthetized mouse. If their technique worked, the mouse would glow in the dark.

16 Feb 2017

Canadian researchers use gene therapy to treat patient with Fabry disease

A team of Canadian physicians and researchers is believed to be the first in the world to have used gene therapy to treat a patient with Fabry disease, a rare inherited enzyme deficiency that can damage major organs and shorten lifespan.

16 Feb 2017

UAB researchers show how GARP2 protein accelerates retinal degeneration in mice

In the retina of the eye, rod and cone cells turn light into electrical signals, the first step toward human vision.

16 Feb 2017

IBS scientists modify fat content in soybean oil using new CRISPR-Cpf1 technology

A team from the Center for Genome Engineering, within the Institute for Basic Research (IBS), succeeded in editing two genes that contribute to the fat contents of soybean oil using the new CRISPR-Cpf1 technology: an alternative of the more widely used gene editing tool CRISPR-Cas9. The results of this new plant gene editing method, applied to soybeans and wild tobacco genes, are published in Nature Communications.

16 Feb 2017

UNIGE researchers develop new technique to improve diagnosis of genetic diseases

When a child is conceived, he or she receives DNA from both parents. The child's own genome thus consists of a maternal and a paternal genome. However, some genes — about 100 out of the 20,000 encoded genes— are exclusively expressed either from the maternal or from the paternal genome, with the other copy of the gene remaining silent.

16 Feb 2017

New report highlights serious health problems faced by spinal cord injury patients

Paralysis is just one of the many serious health problems faced by patients who suffer spinal cord injuries.

16 Feb 2017

Gene therapy treats myotubular myopathy in dogs

The rare disorder, called myotubular myopathy, or MTM, affects only males. It causes fatal muscle wasting. Both dogs and boys with the disease typically succumb in early life due to breathing difficulties.

16 Feb 2017

Salk scientists use mRNA to successfully treat hemophilia B in mice

FedEx, UPS, DHL--when it comes to sending packages, choices abound. But the most important delivery service you may not have heard of mRNA.

16 Feb 2017

Yale researchers find potential new way to combat brain cancer

A recent Yale study may have found a new way to fight brain cancer.

15 Feb 2017

Signals from fat cells may aid in diagnostics for metabolic conditions

Fat cells are not simply big blobs of lipid quietly standingby in the body--instead, they send out hormones and other signaling proteins that affect many types of tissues.

15 Feb 2017

Naturally occurring protein shows promise as biocontrol weapon against schistosomiasis

A naturally occurring protein has been discovered that shows promise as a biocontrol weapon against schistosomiasis, one of the world's most prevalent parasitic diseases, Oregon State University researchers reported today in a new study.

15 Feb 2017

TSRI scientists target obesity-linked protein to prevent weight gain in animal models

Scientists are working to understand the mechanisms that make weight loss so complicated. Exercise burns calories, of course, but scientists are also looking at how the body burns more energy to stay warm in cold temperatures.

15 Feb 2017

UNIST researchers make breakthrough in search for potential root causes of bipolar disorder

A team of researchers, affiliated with UNIST has made a significant breakthrough in the search for the potential root causes of bipolar disorder.

15 Feb 2017

Scientists develop new bioinformatics tool to make biological experiments more transparent

Biological experiments are generating increasingly large and complex sets of data. This has made it difficult to reproduce experiments at other research laboratories in order to confirm - or refute - the results.

15 Feb 2017

Researchers discover sulfide-responsive protein that regulates photosynthesis in purple bacteria

Recent evidence demonstrates that the origins of photosynthesis can be found in deep sea hydrothermal vents, where microbes evolved to obtain energy from ejected hydrogen sulfide and methane gases.

15 Feb 2017

Gene News and Research

Latest Gene News and Research

UT Southwestern scientists unravel role of PARP enzymes in major cellular activities

Discovery of 'molecular switch' could lead to effective new treatments for auto-immune diseases

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

HMS scientists listen to crosstalk between gut microbes and immune system

Glowing mice could mark major step forward for new gene therapy

Canadian researchers use gene therapy to treat patient with Fabry disease

UAB researchers show how GARP2 protein accelerates retinal degeneration in mice

IBS scientists modify fat content in soybean oil using new CRISPR-Cpf1 technology

UNIGE researchers develop new technique to improve diagnosis of genetic diseases

New report highlights serious health problems faced by spinal cord injury patients

Gene therapy treats myotubular myopathy in dogs

Salk scientists use mRNA to successfully treat hemophilia B in mice

Yale researchers find potential new way to combat brain cancer

Signals from fat cells may aid in diagnostics for metabolic conditions

Naturally occurring protein shows promise as biocontrol weapon against schistosomiasis

TSRI scientists target obesity-linked protein to prevent weight gain in animal models

UNIST researchers make breakthrough in search for potential root causes of bipolar disorder

Scientists develop new bioinformatics tool to make biological experiments more transparent

Researchers discover sulfide-responsive protein that regulates photosynthesis in purple bacteria

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