Gene News and Research

Latest Gene News and Research

IMB researchers unveil mystery of aging process

Researchers at the Institute of Molecular Biology in Mainz have made a breakthrough in understanding the origin of the aging process. They have identified that genes belonging to a process called autophagy, which is one of the cells most critical survival processes, promote health and fitness in young worms but drive the process of aging later in life.

27 Sep 2017

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

My research uses budding yeast as a tool for synthetic biology, and also in chemical and functional genomic applications. We are interested in understanding molecular mechanisms and metabolic pathways of yeast for drug discovery.

From Tecan 27 Sep 2017

Genetic testing can improve safety of common blood thinner, study shows

Warfarin is a blood thinner that is commonly prescribed to patients to prevent life-threatening blood clots. Despite its longtime use, warfarin remains tricky to dose because a person's genetic makeup influences how the drug is processed in the body.

27 Sep 2017

Trial identifies genetic fault that affects treatment response in leukemia patients

A genetic fault has been identified in people with an aggressive type of leukemia that can significantly affect how they respond to treatment.

27 Sep 2017

Sophisticated 'social control' system allows embryos to protect purity of pluripotent cell population

A sophisticated system of 'social control' operating between neighboring cells allows embryos to protect the purity of their pluripotent cell population, which is able to generate all body tissues.

27 Sep 2017

Adding, removing water from a stem cell can determine its role as bone or fat

Adding or removing water from a stem cell can change the destiny of the cell, researchers have discovered in a new study published in the Proceedings of the National Academy of Sciences.

27 Sep 2017

MIT study sheds light on flu viruses' rapid evolution

Influenza viruses mutate rapidly, which is why flu vaccines have to be redesigned every year. A new study from MIT sheds light on just how these viruses evolve so quickly and offers a potential way to slow them down.

26 Sep 2017

Injections of hunger hormone blocker can halt typical weight gain in mice

Mayo Clinic scientists have shown that injections of a hunger hormone blocker in mice can halt the typical weight gain after dieting and help prevent rebound obesity in the long term. The research findings appear in the Proceedings of the National Academy of Sciences.

26 Sep 2017

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

26 Sep 2017

Study: Gene linked to schizophrenia risk controls early neurodevelopment

A gene associated with the risk of schizophrenia regulates critical components of early brain development, according to a new study led by researchers from Penn State University.

26 Sep 2017

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Pediatric researchers investigating the childhood cancer neuroblastoma have identified common gene variants that raise the risk of an aggressive form of that disease. The discovery may assist doctors in better diagnosing subtypes of neuroblastoma.

25 Sep 2017

Rutgers scientists use genetic engineering technique to create brain cells for studying Tourette’s

Scientists at Rutgers University-New Brunswick used a genetic engineering technique for the first time to create brain cells from the blood cells of individuals in a three-generation family with Tourette syndrome to help determine what causes the disease.

25 Sep 2017

Mother's diet during pregnancy could affect brain reward circuitry of children

Researchers in France found that rats who ate a junk food diet during pregnancy had heavier pups that strongly preferred the taste of fat straight after weaning. While a balanced diet in childhood seemed to reduce the pups' desire for fat, they nevertheless showed altered brain reward circuitry into adulthood.

25 Sep 2017

“Super malaria” resistant to standard medications in South East Asia

The spread of a single multidrug resistant malaria parasite strain in Vietnam is cause for alarm say researchers.

25 Sep 2017

UAB researchers detail underlying mechanism leading to age-associated osteoporosis

A major health problem in older people is age-associated osteoporosis -- the thinning of bone and the loss of bone density that increases the risk of fractures. Often this is accompanied by an increase in fat cells in the bone marrow.

22 Sep 2017

Study identifies two genes involved in invasive group A Streptococcus infections

Group A Streptococcus bacteria cause a variety of illnesses that range from mild nuisances like strep throat to life-threatening conditions including pneumonia, toxic shock syndrome and the flesh-eating disease formally known as necrotizing fasciitis.

22 Sep 2017

Genome-wide study reveals how transposons get prepared for jumping

The genome of a typical organism consists of many genes that are stringed like beads. This alignment has been surprisingly stable even over very long evolutionary periods. In addition to these genes, there are also many mobile elements, referred to as parasitic, that are spread across the whole genome and aggregated into different families according to their relatedness.

22 Sep 2017

Multi-gene test found to be better at identifying older adults at risk for Alzheimer's

A new test that combines the effects of more than two dozen genetic variants, most associated by themselves with only a small risk of Alzheimer's disease, does a better job of predicting which cognitively normal older adults will go on to develop Alzheimer's dementia than testing only for the well-known genetic variant APOE E4, a scientific team led by researchers at UC San Francisco and UC San Diego has found.

22 Sep 2017

Novel approach facilitates long-term persistence of AAV vector genomes in proliferating cells

Researchers added a scaffold/matrix attachment region (S/MAR) to a conventional adeno-associated virus (AAV) vector used for gene transfer, and the modified vectors were able to establish colonies and maintain long-term transgene expression in HeLa cells, as reported in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

22 Sep 2017

Targeting mutant p53 specific binding protein could lead to new therapeutic strategies for cancer patients

Research by Rutgers Cancer Institute of New Jersey investigators shows the targeting of a binding protein of mutant p53 known as Rac1 could lead to new therapeutic strategies for patients whose cancer carries mutations in the p53 gene.

22 Sep 2017

Gene News and Research

Latest Gene News and Research

IMB researchers unveil mystery of aging process

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

Genetic testing can improve safety of common blood thinner, study shows

Trial identifies genetic fault that affects treatment response in leukemia patients

Sophisticated 'social control' system allows embryos to protect purity of pluripotent cell population

Adding, removing water from a stem cell can determine its role as bone or fat

MIT study sheds light on flu viruses' rapid evolution

Injections of hunger hormone blocker can halt typical weight gain in mice

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Study: Gene linked to schizophrenia risk controls early neurodevelopment

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Rutgers scientists use genetic engineering technique to create brain cells for studying Tourette’s

Mother's diet during pregnancy could affect brain reward circuitry of children

“Super malaria” resistant to standard medications in South East Asia

UAB researchers detail underlying mechanism leading to age-associated osteoporosis

Study identifies two genes involved in invasive group A Streptococcus infections

Genome-wide study reveals how transposons get prepared for jumping

Multi-gene test found to be better at identifying older adults at risk for Alzheimer's

Novel approach facilitates long-term persistence of AAV vector genomes in proliferating cells

Targeting mutant p53 specific binding protein could lead to new therapeutic strategies for cancer patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)