Gene News and Research

Latest Gene News and Research

Researchers use genomics to advance understanding of Parkinson´s disease

It is widely known that genomics has already begun to influence medicine and that bioinformatics holds the key for developing new medical approaches, but how does medical genomics really work?

19 Dec 2017

Researchers link stress-related genetic changes to suicide risk and psychiatric illness

Researchers have linked genetic changes in the so-called CRH gene, which affects the regulation of the body's stress system, to suicide risk and psychiatric illness.

19 Dec 2017

Study shows vital role for maternally inherited gene in embryonic development

A new study indicates an essential role for a maternally inherited gene in embryonic development. The study found that zebrafish that failed to inherit specific genetic instructions from mom developed fatal defects earlier in development, even if the fish could make their own version of the gene.

18 Dec 2017

Researchers identify novel mechanism that protects from brain tumor

A group of researchers at the Spanish National Cancer Research Centre have identified a protein called RanBP6 as a new regulator of EGFR. In a paper published in Nature Communications they show how silencing of RanBP6 promoted glioma growth, by upregulating EGFR expression.

18 Dec 2017

Moderate exercise reduces progression of Marfan syndrome symptoms in mice

Regular physical activity is a common therapy for people with cardiovascular problems, but not recommended to those with Marfan syndrome, a rare disease of the connective tissue, but mainly affecting the cardiovascular system.

18 Dec 2017

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

When a coronary artery is obstructed by atheroma, blood flow is depressed or even arrested. This causes hypoxia of cardiac cells associated with the deprivation of nutrients. In clinic, the first objective is to restore blood flow. However, this is associated with a burst in oxidation of cellular proteins and lipids. This oxidation enhances cell death and participates to the so-called reperfusion injury.

From Logos Biosystems 18 Dec 2017

A guide to Severe Combined Immunodeficiency Disease, review released

A new review published today in the Canadian Medical Association Journal provides guidance on Severe Combined Immunodeficiency Disease (SCID), a deadly and rare disease that is potentially curable if detected early.

18 Dec 2017

New review provides guidance to doctors who may treat infants with ‘bubble boy disease’

A new review provides guidance on a deadly, but rare, disease that is potentially curable if identified early. Severe combined immunodeficiency disease (SCID), known as the "bubble boy disease" in the 1970s, is treatable with a stem cell transplant, gene therapy and other treatments if identified at birth or soon after.

18 Dec 2017

Gene that could be associated with reduced pain response found

Researchers found an Italian family, the Marsilis that have six individuals who respond significantly differently to pain than others. This includes a 78-year-old lady and her two daughters and their three children.

18 Dec 2017

Prostate cancer researchers find significant disparities between two liquid biopsy providers

Two Johns Hopkins prostate cancer researchers found significant disparities when they submitted identical patient samples to two different commercial liquid biopsy providers.

15 Dec 2017

Long-term U-M study yields framework that could be useful for studying bipolar disorder

Nearly 6 million Americans have bipolar disorder, and most have probably wondered why. After more than a decade of studying over 1,100 of them in-depth, a University of Michigan team has an answer – or rather, seven answers.

15 Dec 2017

Researchers uncover THOR gene involved in cancer development

It turns out Thor, the Norse god of thunder and the Marvel superhero, has special powers when it comes to cancer too.

15 Dec 2017

Researchers examine human mutations' impact on therapeutic effect of medicine

Every person has a unique DNA sequence in their genome. Now researchers from the University of Copenhagen and the MRC Laboratory of Molecular Biology in Cambridge have tried to quantify what these differences in the genome mean in the context of the genes targeted by drugs.

15 Dec 2017

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Cancer cells arise when DNA is mutated, and these cells should be recognized as "foreign" by the immune system. However, cancer cells have found ways to evade detection by the immune system.

15 Dec 2017

Rare gene mutation gives rise to low sensitivity to pain

Researchers at University College London have identified a rare gene mutation in an Italian family who have little sensitivity to some forms of pain. Chronic pain caused by conditions such as lower back pain and osteoarthritis is one of the most prominent causes of disability worldwide, as assessed by the Global Burden of Disease reviews.

15 Dec 2017

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

Predicting how patients will respond to anti-cancer therapies can be vital in informing clinical decisions and improving treatment outcome.

15 Dec 2017

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Researchers at Kanazawa University report in EMBO Reports, 7 December 2017, new molecular mechanisms regulating cellular fate of squamous cell carcinomas.

15 Dec 2017

Scientists create atomic scale map that tracks how brain signals connect to neurons

Scientists at Johns Hopkins have used supercomputers to create an atomic scale map that tracks how the signaling chemical glutamate binds to a neuron in the brain. The findings, say the scientists, shed light on the dynamic physics of the chemical's pathway, as well as the speed of nerve cell communications.

15 Dec 2017

Inherited gene variation may be to blame for poor survival of patients with early-onset breast cancer

A new study led by scientists at the University of Southampton has found that inherited variation in a particular gene may be to blame for the lower survival rate of patients diagnosed with early-onset breast cancer.

14 Dec 2017

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

A fusion gene is a single composite gene that is the result of the combination of two formerly independent genes. Researchers from Kumamoto University, Japan have determined that a particular fusion gene has a tendency to be found in cutaneous squamous cell carcinoma (cSCC) lesions on skin exposed frequently to the sun.

14 Dec 2017

Gene News and Research

Latest Gene News and Research

Researchers use genomics to advance understanding of Parkinson´s disease

Researchers link stress-related genetic changes to suicide risk and psychiatric illness

Study shows vital role for maternally inherited gene in embryonic development

Researchers identify novel mechanism that protects from brain tumor

Moderate exercise reduces progression of Marfan syndrome symptoms in mice

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

A guide to Severe Combined Immunodeficiency Disease, review released

New review provides guidance to doctors who may treat infants with ‘bubble boy disease’

Gene that could be associated with reduced pain response found

Prostate cancer researchers find significant disparities between two liquid biopsy providers

Long-term U-M study yields framework that could be useful for studying bipolar disorder

Researchers uncover THOR gene involved in cancer development

Researchers examine human mutations' impact on therapeutic effect of medicine

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Rare gene mutation gives rise to low sensitivity to pain

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Scientists create atomic scale map that tracks how brain signals connect to neurons

Inherited gene variation may be to blame for poor survival of patients with early-onset breast cancer

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition)

Fourier 80: bringing benchtop NMR systems to the laboratory

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