Gene News and Research

Latest Gene News and Research

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Advanced engineering of a mini-intronic plasmid (MIP) system designed to carry a therapeutic gene can significantly enhance the expression of the transgene delivered using an adeno-associated viral (AAV) vector.

28 Jan 2017

Studies show prevalence of multi-drug resistant bacteria in China

The mcr-1 gene--a gene that makes bacteria resistant to colistin, an antibiotic of last resort, and that is transferrable between bacteria--has been found in a wide variety of strains of Escherichia coli in China following widespread use of colistin in agriculture.

28 Jan 2017

Interventions that change the brain may promote resilience and improved mental health

In an article published in the current issue of Psychotherapy and Psychosomatic Dr. Bruce McEwen (Rockefeller University) analyzes promising outlooks that interventions that affect brain may have on health.

28 Jan 2017

Both accelerator and brake in the brain control all types of movements, research shows

In order to drive a car, you need a good balance between accelerator and brake. The same applies to a part of the brain - the striatum - that controls our movements.

28 Jan 2017

Scientists identify key 'survival gene' that reduces mutation rates in mycobacteria

Scientists have discovered a key 'survival gene' that prevents strains of tuberculosis (TB) from mutating into drug-resistant 'superbugs'.

28 Jan 2017

New study explores how protein production goes off script when skin cells turn cancerous

Each cell in the body follows a strict protocol for manufacturing the proteins it needs to function.

27 Jan 2017

TSRI biologists identify brain hormone that selectively stimulates fat metabolism

Biologists at The Scripps Research Institute have identified a brain hormone that appears to trigger fat burning in the gut. Their findings in animal models could have implications for future pharmaceutical development.

27 Jan 2017

Light emitted from digital screens can cause irreversible damage to eyes, research shows

The University Complutense of Madrid (UCM), one of the oldest Universities in the world, presents the results of its latest research confirming the irreversible damage to animals’ eyes caused by light emitted from digital screens.

27 Jan 2017

Stem cell secretions appear to protect retinal ganglion cells in rats, study shows

A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye.

27 Jan 2017

New gene therapy for Pompe disease may replace currently available treatments

After decades investigating a rare, life-threatening condition that cripples the muscles, Duke Health researchers have developed a gene therapy they hope could enhance or even replace the only FDA-approved treatment currently available to patients.

27 Jan 2017

Novel gene therapy restores partial hearing and balance in mice born with genetic deafness

Using a novel form of gene therapy, scientists from Harvard Medical School and the Massachusetts General Hospital have managed to restore partial hearing and balance in mice born with a genetic condition that affects both.

27 Jan 2017

Old tuberculosis drug improves impaired social behavior in autism mouse model

Reducing the function of the autism-associated gene Pcdh10 leads to impairments in social behavior, according to a study published in Biological Psychiatry.

26 Jan 2017

Researchers identify novel risk genes linked to bipolar disorder

Bipolar disorder (BD), characterized by mood swings between positive manic/hypomanic and negative/depressive states, is a common psychiatric disorder with a lifetime prevalence of ~1%.

26 Jan 2017

Missing gene may cause kidney and urinary tract defects in people with DiGeorge syndrome

Loss of function of the CRKL gene causes kidney and urinary tract defects in people with DiGeorge syndrome, a multinational team of scientists led by Columbia University Medical Center has found.

25 Jan 2017

Researchers map genetic changes resulting from short bowel syndrome

Investigators at Children's Hospital Los Angeles, led by Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short bowel syndrome using a novel zebrafish model and by performing intensive gene sequencing.

25 Jan 2017

Study suggests best sequence of therapies for brain metastases in EGFR mutant lung cancer patients

About 10 percent of lung cancers in the United States and as many as 40 percent in Asia are driven by mutations in the EGFR gene.

25 Jan 2017

HCI scientists uncover new way that bones get destroyed through breast cancer

Once breast cancer spreads through the body, it can degrade a patient's healthy bones, causing numerous problems. Scientists at Huntsman Cancer Institute at the University of Utah have identified a new way that bones get destroyed through cancer.

25 Jan 2017

Prenatal infection-induced epigenetic modifications may alter brain development in offspring

Maternal infection during pregnancy increases the risk for psychiatric disorders in the child, but the path between the two is something of a mystery.

25 Jan 2017

BRCA1 gene required for survival of blood forming stem cells, UT Southwestern study finds

Researchers at from the Harold C. Simmons Comprehensive Cancer Center have found that the BRCA1 gene is required for the survival of blood forming stem cells, which could explain why patients with BRCA1 mutations do not have an elevated risk for leukemia.

25 Jan 2017

Scientists discover new way to inhibit growth of glioblastoma

Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O'Donnell Jr. Brain Institute and Harold C. Simmons Comprehensive Cancer Center.

25 Jan 2017

Gene News and Research

Latest Gene News and Research

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Studies show prevalence of multi-drug resistant bacteria in China

Interventions that change the brain may promote resilience and improved mental health

Both accelerator and brake in the brain control all types of movements, research shows

Scientists identify key 'survival gene' that reduces mutation rates in mycobacteria

New study explores how protein production goes off script when skin cells turn cancerous

TSRI biologists identify brain hormone that selectively stimulates fat metabolism

Light emitted from digital screens can cause irreversible damage to eyes, research shows

Stem cell secretions appear to protect retinal ganglion cells in rats, study shows

New gene therapy for Pompe disease may replace currently available treatments

Novel gene therapy restores partial hearing and balance in mice born with genetic deafness

Old tuberculosis drug improves impaired social behavior in autism mouse model

Researchers identify novel risk genes linked to bipolar disorder

Missing gene may cause kidney and urinary tract defects in people with DiGeorge syndrome

Researchers map genetic changes resulting from short bowel syndrome

Study suggests best sequence of therapies for brain metastases in EGFR mutant lung cancer patients

HCI scientists uncover new way that bones get destroyed through breast cancer

Prenatal infection-induced epigenetic modifications may alter brain development in offspring

BRCA1 gene required for survival of blood forming stem cells, UT Southwestern study finds

Scientists discover new way to inhibit growth of glioblastoma

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