Gene News and Research

Latest Gene News and Research

Specific protein negatively affects pancreatic cells and leads to cancer growth

Pancreatic cancer is one of the most aggressive forms of cancer and is currently very difficult to treat. However, the last few years have seen advances in the scientific understanding of how this cancer develops at a molecular level.

6 Dec 2017

Immune-boosting drug combination may hold promise for treating ovarian cancer

Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor burden and significantly longer survival than those that received any of the drugs alone.

5 Dec 2017

New study examines effects of gene variant on resting-state brain function in patients with MDD

A new study assessed the effects of a SLC6A15 gene variant on resting-state brain function in patients with major depressive disorder (MDD), comparing the results with those in healthy individuals.

5 Dec 2017

Study uncovers genes that drive peanut allergy reactions

Mount Sinai researchers have identified six genes that activate hundreds of other genes in children experiencing severe allergic reactions to peanuts.

5 Dec 2017

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

The investigational Zika purified inactivated virus (ZPIV) vaccine was well-tolerated and induced an immune response in participants, according to initial results from three Phase 1 clinical trials.

5 Dec 2017

DNA sequencing could identify genetic cause of kidney disease

DNA sequencing could soon become part of the routine diagnostic workup for patients with chronic kidney disease, suggests a new study from Columbia University Medical Center.

5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

New biomarker test can accurately predict which chemical compounds induce DNA damage

A new biomarker test developed by researchers at Georgetown Lombardi Comprehensive Cancer Center and their colleagues can help predict, with up to 90 percent certainty, which chemical compounds can cause DNA damage that could lead to cancer.

5 Dec 2017

Scientists investigate new role of old protein in breast cancer

Scientists led by Dr Chris Toseland of the University's School of Biosciences studied a protein called Myosin VI, a molecular motor which acts as a courier to transport other proteins within our cells.

4 Dec 2017

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Children with an extremely deadly form of brain cancer might benefit from a new treatment that aims to direct an immune response against an abnormally shaped protein found exclusively on cancer cells, according to a new study led by UC San Francisco researchers.

4 Dec 2017

Study reveals gene linked to metastatic melanoma

A study by Craig J. Ceol, PhD, assistant professor of molecular medicine at the University of Massachusetts Medical School, has revealed a protein active during early embryo development called GDF6 plays a primary role in metastatic melanoma.

4 Dec 2017

FDA grants approval to first biosimilar for treatment of patients with breast, stomach cancers

The U.S. Food and Drug Administration today approved Ogivri (trastuzumab-dkst) as a biosimilar to Herceptin (trastuzumab) for the treatment of patients with breast or metastatic stomach cancer (gastric or gastroesophageal junction adenocarcinoma) whose tumors overexpress the HER2 gene (HER2+).

4 Dec 2017

Innovative nanoparticle-based approach to fight myocardial infarction

How can damaged cardiac tissue following a heart attack best be treated with replacement muscle cells? A research team under the supervision of the University of Bonn is now presenting an innovative method on mice: Muscle replacement cells, which are to take over the function of the damaged tissue, are loaded with magnetic nanoparticles.

1 Dec 2017

Study identifies cluster of dysregulated genes in pancreatic islets of type 2 diabetes patients

Type 2 diabetes, which affects >0.5 billion people worldwide, results from the inability of beta cells in the pancreatic islets to provide the body with enough insulin to maintain blood glucose levels within the range for a healthy life.

1 Dec 2017

Study provides insights on mechanisms involved in tolerance after kidney transplantation

A new study provides insights on the mechanisms that allow an individual's immune system to accept, rather than reject, a donor kidney. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, point to markers that could be monitored to assess and track the health of organs following transplantation.

1 Dec 2017

Australian researchers develop new risk scoring system to predict childhood leukemia relapse

Australian researchers have developed a new risk scoring system for children with leukemia based on missing DNA fragments or 'microdeletions'.

1 Dec 2017

Researchers identify vulnerability for glioblastoma subtypes

Glioblastoma, the most common and aggressive form of brain cancer, typically fails to respond to treatment or rapidly becomes drug resistant.

1 Dec 2017

Scientists identifies new genetic changes that increase risk of developing Hodgkin lymphoma

People who inherit genetic changes which alter the function of their immune system are at increased risk of developing Hodgkin lymphoma, a major new study reports.

1 Dec 2017

Orchard Therapeutics opens new facility for technical operations in San Francisco Bay area

Orchard Therapeutics, a clinical-stage biotechnology company dedicated to transforming the lives of patients with rare disorders through innovative gene therapies, today announced the opening of a second facility for technical operations in the San Francisco Bay Area.

1 Dec 2017

New drugs Erenumab and Fremanezumab show promise for migraine

Migraine headaches affect thousands of Americans and millions worldwide. There are several medications that are being prescribed for migraines and for many these do not work well.

30 Nov 2017

Gene News and Research

Latest Gene News and Research

Specific protein negatively affects pancreatic cells and leads to cancer growth

Immune-boosting drug combination may hold promise for treating ovarian cancer

New study examines effects of gene variant on resting-state brain function in patients with MDD

Study uncovers genes that drive peanut allergy reactions

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

DNA sequencing could identify genetic cause of kidney disease

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

New biomarker test can accurately predict which chemical compounds induce DNA damage

Scientists investigate new role of old protein in breast cancer

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Study reveals gene linked to metastatic melanoma

FDA grants approval to first biosimilar for treatment of patients with breast, stomach cancers

Innovative nanoparticle-based approach to fight myocardial infarction

Study identifies cluster of dysregulated genes in pancreatic islets of type 2 diabetes patients

Study provides insights on mechanisms involved in tolerance after kidney transplantation

Australian researchers develop new risk scoring system to predict childhood leukemia relapse

Researchers identify vulnerability for glioblastoma subtypes

Scientists identifies new genetic changes that increase risk of developing Hodgkin lymphoma

Orchard Therapeutics opens new facility for technical operations in San Francisco Bay area

New drugs Erenumab and Fremanezumab show promise for migraine

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition)

Fourier 80: bringing benchtop NMR systems to the laboratory

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