Gene News and Research

Latest Gene News and Research

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

Previous studies at the University of Colorado Cancer Center show that the experimental drug AMPI-109 potently kills triple-negative breast cancer cells.

30 Aug 2016

KU Leuven researchers use microbubbles to evaluate effectiveness of cancer radiation treatment

An interdisciplinary team of researchers at KU Leuven (University of Leuven), Belgium, have developed a new way to evaluate whether a cancer radiation treatment is effective.

30 Aug 2016

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

A study in The Journal of Cell Biology by scientists at the University of Massachusetts Medical School reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene editing tool.

30 Aug 2016

Penn scientists find striking similarities between human patients with LCA and dogs

Ciliopathies are diseases that affect the cilia, sensory organelles that most mammalian cells possess and which play a critical role in many biological functions.

30 Aug 2016

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

In microseconds, every light ray that enters the eye triggers an explosion of coordinated cellular events.

29 Aug 2016

Studying mutant peptides may help detect weaknesses in tumor cells

Researchers from MIPT, the Institute of Biomedical Chemistry, the Institute for Energy Problems of Chemical Physics, and the Research Institute of Physico-Chemical Medicine have presented an algorithm to detect mutant proteins based on mass spectrometry data and the results of exome sequencing.

29 Aug 2016

Nicotinic receptors could be new therapeutic target to prevent memory loss linked to Alzheimer's

Several scientific studies have indicated that nicotine may be beneficial for memory function.

29 Aug 2016

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

BRAF mutation occurs in between 40% and 50% of metastasising melanomas (skin cancers), boosting tumour growth.

29 Aug 2016

Is the virtual gene panel the way forward asks Congenica at Dx Summit

Although the current practice of analysing defined gene panels for a specific disease has great utility, it is of limited benefit when a condition is not well defined.

29 Aug 2016

NEJM publishes MINDACT trial results

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, announces the peer-reviewed publication of the primary outcome results of the Microarray In Node-negative and 1 to 3 positive lymph node Disease may Avoid ChemoTherapy (MINDACT) clinical trial in the prestigious New England Journal of Medicine (NEJM). (i, iii, iv) The publication demonstrates that 46% of breast cancer patients considered for chemotherapy, whose tumors are classified MammaPrint Low Risk, have excellent survival without chemotherapy, and can thus be candidates to avoid this toxic therapy.

29 Aug 2016

NanoScope awarded AGI Grant to re-sensitize photo-degenerated retinal areas with MCO

Millions of individuals affected by Retinitis Pigmentosa (RP) are visually impaired due to photo-degeneration of retina. The visual loss starts with the peripheral region progressing towards the center leading to tunnel vision. Currently, there is no cure to restore vision in these patients. The disease leads not only to physical impairment, but has a significant emotional and psychological impact on quality of life of patients as well as their family members.

27 Aug 2016

Basic cell biology research into neurodegeneration may fuel understanding of neurodegenerative diseases

Clinical trials and translational medicine have certainly given people hope and rapid pathways to cures for some of mankind's most troublesome diseases, but now is not the time to overlook the power of basic research, says UC Santa Barbara neuroscientist Kenneth S. Kosik.

27 Aug 2016

Study suggests microRNAs may connect inflammation with heart disease risk in obese people

Inflammation likely plays a role in the increased risk of heart disease that comes with obesity, but scientists don't fully understand how obesity leads to heart disease.

26 Aug 2016

Researchers explore molecular mechanisms through which lead exposure may affect neural stem cells

Researchers have identified a potential molecular mechanism through which lead, a pervasive environmental toxin, may harm neural stem cells and neurodevelopment in children.

26 Aug 2016

SSRI treatment improves cognitive and social functioning in young children with fragile X

Treatment with sertraline may provide nominal but important improvements in cognition and social participation in very young children with fragile X syndrome, the most common genetic cause of intellectual disability and the leading single-gene cause of autism, a study by researchers with the UC Davis MIND Institute has found.

26 Aug 2016

Gene News and Research

Latest Gene News and Research

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

KU Leuven researchers use microbubbles to evaluate effectiveness of cancer radiation treatment

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

Penn scientists find striking similarities between human patients with LCA and dogs

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

Studying mutant peptides may help detect weaknesses in tumor cells

Nicotinic receptors could be new therapeutic target to prevent memory loss linked to Alzheimer's

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

Is the virtual gene panel the way forward asks Congenica at Dx Summit

NEJM publishes MINDACT trial results

NanoScope awarded AGI Grant to re-sensitize photo-degenerated retinal areas with MCO

Basic cell biology research into neurodegeneration may fuel understanding of neurodegenerative diseases

Study suggests microRNAs may connect inflammation with heart disease risk in obese people

Researchers explore molecular mechanisms through which lead exposure may affect neural stem cells

SSRI treatment improves cognitive and social functioning in young children with fragile X

Kobe University researchers develop new technique for high-level genome editing operation

Naturally-occurring sugars in woman's breast milk may protect infants against life threatening bacteria

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

Study reveals how pluripotency differs among mice, monkeys, and humans

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

Industry Focus: Cell & Gene Therapy eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research