Gene News and Research

Latest Gene News and Research

Study identifies new gene that suppresses breast cancer in mice

In recent years, the incidence of breast cancer has been increasing worldwide, and breast cancer is becoming a serious object of public concern.

13 Sep 2016

New dermatological treatment could potentially help prevent or reverse diabetic neuropathy

For the 25 percent of type-2 diabetes patients who suffer from numbness and extreme nerve pain in their feet, a new dermatological treatment being tested by Northwestern Medicine scientists could potentially help prevent and maybe even reverse the neuropathy.

13 Sep 2016

ATR inhibitors show improved survival and effectiveness in animal models of cancer

Tumours are an accumulation of cells that divide without control, accumulating hundreds of chromosomal alterations and mutations in their DNA.

13 Sep 2016

Researchers identify genes that regulate cellular senescence

A research group including Professor KAMADA Shinji, Research Fellow NAGANO Taiki (both from the Kobe University Biosignal Research Center), and Unit Chief ENARI Masato (National Cancer Research Institute) has succeeded in identifying genes that control cellular senescence - permanently arrested cell growth.

13 Sep 2016

Novel DNA-altering method could lead to more treatment options for diseases

Researchers in Singapore have developed a new protein that can alter DNA in living cells with much higher precision than current methods.

13 Sep 2016

NUS study reveals RNA editing events play vital role in gastric cancer development

A team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has found that changes in ribonucleic acid (RNA) sequences play a major role in the development of gastric cancer.

13 Sep 2016

New four-stranded version of DNA may hold key to development of targeted cancer therapies

Scientists have identified where a four-stranded version of DNA exists within the genome of human cells, and suggest that it may hold a key to developing new, targeted therapies for cancer.

13 Sep 2016

International researchers discover 44 novel gene sites linked to hypertension

In papers receiving advance online publication in Nature Genetics, two international multi-institutional research teams describe identifying a total of 44 novel gene sites associated with hypertension or high blood pressure.

13 Sep 2016

Combinational analysis of FISH and IHC detects NSCLC patients with rare ALK fusions

The combined use of fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) identified non-small cell lung cancer (NSCLC) patients with rare or novel anaplastic lymphoma kinase (ALK) gene rearrangements, not otherwise identified by FISH alone, that showed response to crizotinib treatment.

12 Sep 2016

Researchers uncover specific sites in the genome linked to high blood pressure

Three large, collaborating international consortia of researchers, including a team co-led by investigators from Brigham and Women's Hospital, have uncovered new genes and sites in the genome tied to elevated blood pressure, implicating certain biological pathways and pointing toward new therapeutic strategies for treating hypertension.

12 Sep 2016

Study reveals promising strategy against bladder cancer metastasis

The popular kids' card game "Exploding Kittens" teaches a concept critical to cancer science: When a player plays a "Nope" card, the subsequent player may lay another "Nope", thus creating a double-negative that becomes a positive, allowing the initial action to proceed.

12 Sep 2016

Novel controlled clinical trial finds Ayurvedic-based well-being program can alter blood-based metabolites

In a novel controlled clinical trial, participants in a six-day Ayurvedic-based well-being program that featured a vegetarian diet, meditation, yoga and massages experienced measurable decreases in a set of blood-based metabolites associated with inflammation, cardiovascular disease risk and cholesterol regulation.

9 Sep 2016

Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Individual cells within a tumor are not all the same. This may sound like a modern medical truism, but it wasn't very long ago that oncologists assumed that taking a single biopsy from a patient's tumor would be an accurate reflection of the physiological and genetic make-up of the entire mass.

9 Sep 2016

Study opens door to new class of therapies for Ras-dependent cancers

New research from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai identifies a protein that may be an unexplored target to develop new cancer therapies.

9 Sep 2016

Research offers new insights into underlying mechanisms of deadly cystic fibrosis

A minor hiccup in the sequence of a human gene can have devastating impacts on health. Such flaws cause cystic fibrosis (CF), a disease affecting the lungs and other vital organs, often leading to death by the age of 30.

9 Sep 2016

New treatment reduces activity of Huntington's disease gene for several months in mice

A single injection of a new treatment has reduced the activity of the gene responsible for Huntington's disease for several months in a trial in mice.

9 Sep 2016

UAB researchers find microRNA as potential therapeutic target for MDD

A tiny RNA appears to play a role in producing major depression, the mental disorder that affects as many as 250 million people a year worldwide.

9 Sep 2016

Liquid biopsies may be effective option for detecting mutations in advanced lung cancer patients

For patients with advanced lung cancer, a non-invasive liquid biopsy may be a more effective and suitable alternative to the gold standard tissue biopsy to detect clinically relevant mutations and help guide their course of treatment, suggests a new study published this week in the journal Clinical Cancer Research from researchers at the Abramson Cancer Center at the University of Pennsylvania.

9 Sep 2016

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists from Jerusalem and Duesseldorf have succeeded in generating induced pluripotent stem cells from a rare disorder called Nijmegen breakage syndrome (NBS) and to push these cells to become early neurons, revealing the mechanisms leading to the neurological phenotype observed in these patients.

9 Sep 2016

Viral vector-based approaches could improve effectiveness of CFTR gene therapy

Cystic fibrosis (CF) is characterized by accumulation of thick mucus in the lungs and is associated with a high incidence of bacterial infection. Mutations in the gene encoding CF transmembrane conductance regulator (CFTR) underlie the disease.

9 Sep 2016

Gene News and Research

Latest Gene News and Research

Study identifies new gene that suppresses breast cancer in mice

New dermatological treatment could potentially help prevent or reverse diabetic neuropathy

ATR inhibitors show improved survival and effectiveness in animal models of cancer

Researchers identify genes that regulate cellular senescence

Novel DNA-altering method could lead to more treatment options for diseases

NUS study reveals RNA editing events play vital role in gastric cancer development

New four-stranded version of DNA may hold key to development of targeted cancer therapies

International researchers discover 44 novel gene sites linked to hypertension

Combinational analysis of FISH and IHC detects NSCLC patients with rare ALK fusions

Researchers uncover specific sites in the genome linked to high blood pressure

Study reveals promising strategy against bladder cancer metastasis

Novel controlled clinical trial finds Ayurvedic-based well-being program can alter blood-based metabolites

Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Study opens door to new class of therapies for Ras-dependent cancers

Research offers new insights into underlying mechanisms of deadly cystic fibrosis

New treatment reduces activity of Huntington's disease gene for several months in mice

UAB researchers find microRNA as potential therapeutic target for MDD

Liquid biopsies may be effective option for detecting mutations in advanced lung cancer patients

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Viral vector-based approaches could improve effectiveness of CFTR gene therapy

Industry Focus: Cell & Gene Therapy eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research