Gene News and Research

Latest Gene News and Research

Researchers unravel how drug interacts with ribosome to halt protein production

The discovery of a chemical compound that halts the production of a small set of proteins while leaving general protein production untouched suggests a new drug search strategy: Find compounds that target undesired proteins before they are even made.

23 Mar 2017

Androgens more important for ovarian development, study suggests

Scientists have discovered that the male "androgen" hormone is an important element in the ovarian development of female chicken embryos, more so than in the development of male testes.

23 Mar 2017

Method used to pick up laboratory mice has major impact on result of mouse studies

A new study shows that how mice are picked up by the experimenter can substantially change their behaviour in cognitive tests. The work, by Dr Kelly Gouveia and Professor Jane Hurst from the University of Liverpool, was published in Scientific Reports today and funded by the NC3Rs .

23 Mar 2017

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have shown that in a mouse model of early stage resected pancreatic cancer, intratumoral vaccination induces an anti-tumor response that results in a significant improvement in overall survival.

23 Mar 2017

Study finds steady increase in BRCA testing among low-risk women

Discovery of the BRCA genetic mutation in the mid-90s represented a breakthrough in breast and ovarian cancer prevention. About 5-10% of breast cancer cases and 10-18% of ovarian cancer cases can be attributed to two BRCA mutations.

23 Mar 2017

Researchers develop novel genetic score to calculate age-specific risk of Alzheimer's disease

An international team of scientists, led by researchers at University of California San Diego School of Medicine and University of California San Francisco, has developed a novel genetic score that allows individuals to calculate their age-specific risk of developing Alzheimer's disease (AD), based upon genetic information.

22 Mar 2017

New genetic biomarker for colon cancer may lead to development of personalized treatment

Researchers at Baylor Scott & White Research Institute identified a new genetic biomarker for colon cancer that may lead to development of more targeted treatment of the disease.

22 Mar 2017

Researchers examine potential for microRNAs to detect gastrointestinal cancer in blood, bodily fluids

Blood tests that could detect cancer before it develops show promise for the future of screening and prevention, though researchers continue to test which cancer clues are good markers for diagnosis.

22 Mar 2017

Heroin use linked to epigenetic alterations in the brain

Heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression, and more years of drug use correlate with higher levels of hyperacetylation, according to research conducted at The Icahn School of Medicine at Mount Sinai and published in the journal Biological Psychiatry.

22 Mar 2017

Researchers develop new software tool to provide fast, accurate quantification of gene expression

A group of computational biological researchers, led by Stony Brook University's Rob Patro, an Assistant Professor in the Department of Computer Science in the College of Engineering and Applied Sciences, has developed a new software tool, Salmon — a lightweight method to provide fast and bias-aware quantification from RNA-sequencing reads.

22 Mar 2017

New technology may provide non-invasive approach to diagnose and monitor prostate cancer

Technology being developed at Washington State University provides a non-invasive approach for diagnosing prostate cancer and tracking the disease's progression.

22 Mar 2017

RUB researchers identify new rare muscle disorder

A new rare muscle disorder has been identified by researchers at Ruhr-Universität Bochum. This hereditary disease is caused by a defect in the BICD2 gene that manifests itself in altered cellular transport processes in skeletal muscle cells.

22 Mar 2017

Researchers uncover gene mutation that may provide answers to unexplained female infertility

Researchers at Baylor College of Medicine, Texas Children's Hospital and Rice University have uncovered a gene mutation that may provide answers to unexplained female infertility. The study appears in Scientific Reports, a member of the Nature family of journals.

22 Mar 2017

Changes in the vascular system could play role in initiating Alzheimer’s disease

As the average age of Americans increases, so too does the problem of Alzheimer's, one of the world's most common neurological diseases. In recent years, scientists have explored many new approaches to clear the plaques and tangles in the brain that characterize the condition, but the new drugs have largely turned out to be disappointing.

22 Mar 2017

USC study close to finding gene involved in cleft lip and palate

A group of researchers has found that three siblings born with cleft lip and palate share a common gene mutation associated with the birth defect.

22 Mar 2017

Penn researcher wins Scientific Innovations Award from Chicago-based Brain Research Foundation

James Eberwine, PhD, the Elmer Holmes Bobst Professor of Systems Pharmacology and Translational Therapeutics at the Perelman School of Medicine at the University of Pennsylvania, has received the 2017 Scientific Innovations Award from the Chicago-based Brain Research Foundation, which supports research for preventing and treating neurological diseases.

22 Mar 2017

Study identifies potential Achilles heel of kinase-driven cancers

Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models.

22 Mar 2017

Research shows how Ohr enzyme plays central role in bacterial anti-oxidant defense

A research project conducted at the University of São Paulo in Brazil in collaboration with other Brazilian research institutions and abroad has revealed new aspects of the action mechanism of organic hydroperoxide resistance (Ohr) enzyme, which enables several species of bacteria to neutralize oxidizing substances released by the defense system of the host organism, be it a plant or an animal.

21 Mar 2017

New study correlates 80 cancer-related gene mutations with 34 AML subgroups

A large, new study of adults with acute myeloid leukemia (AML) correlates 80 cancer-related gene mutations with five subtypes of AML, which are defined by the presence of specific chromosomal abnormalities. The findings might help guide mutation testing and treatment decisions in the future.

21 Mar 2017

Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model

Using a new cellular model, innovative gene therapy approaches for the hereditary immunodeficiency Chronic Granulomatous Disease can be tested faster and cost-effectively in the lab for their efficacy.

21 Mar 2017

Gene News and Research

Latest Gene News and Research

Researchers unravel how drug interacts with ribosome to halt protein production

Androgens more important for ovarian development, study suggests

Method used to pick up laboratory mice has major impact on result of mouse studies

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Study finds steady increase in BRCA testing among low-risk women

Researchers develop novel genetic score to calculate age-specific risk of Alzheimer's disease

New genetic biomarker for colon cancer may lead to development of personalized treatment

Researchers examine potential for microRNAs to detect gastrointestinal cancer in blood, bodily fluids

Heroin use linked to epigenetic alterations in the brain

Researchers develop new software tool to provide fast, accurate quantification of gene expression

New technology may provide non-invasive approach to diagnose and monitor prostate cancer

RUB researchers identify new rare muscle disorder

Researchers uncover gene mutation that may provide answers to unexplained female infertility

Changes in the vascular system could play role in initiating Alzheimer’s disease

USC study close to finding gene involved in cleft lip and palate

Penn researcher wins Scientific Innovations Award from Chicago-based Brain Research Foundation

Study identifies potential Achilles heel of kinase-driven cancers

Research shows how Ohr enzyme plays central role in bacterial anti-oxidant defense

New study correlates 80 cancer-related gene mutations with 34 AML subgroups

Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model

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