Gene News and Research

Latest Gene News and Research

IBBL becomes first biobank to be accredited for next-generation microbial sequencing

Further to a successful follow-up audit, IBBL (Integrated BioBank of Luxembourg) becomes the first biobank worldwide to be accredited for the next-generation 16S rRNA gene sequencing, a cutting-edge method that takes forward research into the human microbiome.

23 Dec 2016

Researchers working to develop pill for inherited bleeding disorders

Motivated by the tribulations of hemophilia patients and their families, researchers funded by the National Institute of Biomedical Imaging and Bioengineering are working to develop a pill to treat this serious inherited bleeding disorder.

23 Dec 2016

Linking human genome sequences to EHR information could influence clinical medicine, says expert

The value of intersecting the sequencing of individuals' exomes or full genomes to find rare genetic variants -- on a large scale -- with their detailed electronic health record information has "myriad benefits, including the illumination of basic human biology, the early identification of preventable and treatable illnesses, and the identification and validation of new therapeutic targets," wrote Daniel J. Rader, MD, chair of the Department of Genetics, in the Perelman School of Medicine at the University of Pennsylvania, in Science this week, with Scott M. Damrauer, MD, an assistant professor of Surgery at Penn and the Veterans Affairs Medical Center in Philadelphia.

23 Dec 2016

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

An international team of scientists has discovered that the gene, OGDHL, a key protein required for normal function of the mitochondria -- the energy-producing factory of the cell -- and its chaperone, nardilysin (NRD1) are linked to progressive loss of neurological function in humans.

22 Dec 2016

Making muscles burn more fat and less glucose could cause diabetes, say researchers

Making muscles burn more fat and less glucose can increase exercise endurance, but could simultaneously cause diabetes, says a team of scientists from Baylor College of Medicine and other institutions.

22 Dec 2016

Scientists identify gene variants causing unrecognized developmental disorder

An international team of scientists has identified variants of the gene EBF3 causing a developmental disorder with features in common with autism.

22 Dec 2016

New computational tool can predict personal cancer driver genes to optimize treatment

Columbia University Medical Center researchers have created a computational tool that can rapidly predict which genes are implicated in an individual's cancer and recommend treatments.

22 Dec 2016

New study explores circadian timekeeping to create genetic knock-out rescue mice

A new study from the laboratory of Hiroki Ueda at the RIKEN Quantitative Biology Center investigates circadian timekeeping with a novel approach to creating genetic knock-out rescue mice.

22 Dec 2016

Gene testing could help predict ovarian cancer patients' sensitivity to new class of drugs

Testing for a gene commonly mutated in ovarian cancers could pick out patients who will respond well to a promising new class of cancer drugs, a major new study reveals.

22 Dec 2016

High BMI leads to epigenetic changes, study shows

The extra pounds you gain during the holidays will not only show up on your hips but will also affect your DNA.

22 Dec 2016

Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, has presented new prospective data demonstrating the strong impact of its 70-Gene Breast Cancer Recurrence assay, MammaPrint, and the corresponding 80-Gene Molecular Subtyping Assay BluePrint, in clinical decision-making for patients with early-stage breast cancer in Germany.

22 Dec 2016

New class of monocyte cells with strange morphology may cause fibrosis

Scientists at the Immunology Frontier Research Center (IFReC) at Osaka University, Japan, report a new group of monocytes they call SatM.

22 Dec 2016

UNC scientists develop new tool to study G-protein signaling

Scientists from the UNC School of Medicine have developed a new tool for studying a key process in cells called G-protein signaling, which plays a central role in the normal functioning of cells and can go awry to cause severe disease, including cancers.

22 Dec 2016

Combined genetic disruptions can counteract premature aging, TSRI study suggests

In a new study, scientists from the Florida campus of The Scripps Research Institute have shown how two genes "balance" each other to maintain normal cell function.

22 Dec 2016

Scientists discover link between Huntington's disease and dysfunction of subthalamic nucleus

Northwestern Medicine scientists identified a link between Huntington's disease and dysfunction of the subthalamic nucleus, a component of the basal ganglia, a group of brain structures critical for movement and impulse control.

21 Dec 2016

Music may regulate mood, emotional responses at behavioral and neuronal level

Sounds, such as music and noise, are capable of reliably affecting individuals' moods and emotions, possibly by regulating brain dopamine, a neurotransmitter strongly involved in emotional behavior and mood regulation.

21 Dec 2016

Researchers find accumulation of tumor suppressor in liver after food withdrawal

Tumor suppressors stop healthy cells from becoming cancerous. Researchers from Charité - Universitätsmedizin Berlin, the Medical University of Graz and the German Institute of Human Nutrition in Potsdam-Rehbruecke have found that p53, one of the most important tumor suppressors, accumulates in liver after food withdrawal.

21 Dec 2016

Fly study shows RNA pathway plays major role in normal health and longevity

Humans and other animals carry rogue sequences of DNA in their genomes called transposable elements. To prevent passing TEs to their offspring, they employ the piRNA pathway in their reproductive organs to block the elements from being active in their sperm and eggs.

21 Dec 2016

Research sheds new light on key drivers of cancer metastasis

Latest research from New Zealand's University of Otago is shedding new light on why and how cancer cells spread from primary tumours to other parts of the body. This phenomenon - known as metastasis - causes about 90 per cent of all cancer deaths.

21 Dec 2016

Researchers engineer promising live-attenuated RSV vaccine candidate

Crafting a vaccine against RSV (respiratory syncytial virus) has been a minefield for 50 years, but scientists believe they have found the right balance.

21 Dec 2016

Gene News and Research

Latest Gene News and Research

IBBL becomes first biobank to be accredited for next-generation microbial sequencing

Researchers working to develop pill for inherited bleeding disorders

Linking human genome sequences to EHR information could influence clinical medicine, says expert

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

Making muscles burn more fat and less glucose could cause diabetes, say researchers

Scientists identify gene variants causing unrecognized developmental disorder

New computational tool can predict personal cancer driver genes to optimize treatment

New study explores circadian timekeeping to create genetic knock-out rescue mice

Gene testing could help predict ovarian cancer patients' sensitivity to new class of drugs

High BMI leads to epigenetic changes, study shows

Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

New class of monocyte cells with strange morphology may cause fibrosis

UNC scientists develop new tool to study G-protein signaling

Combined genetic disruptions can counteract premature aging, TSRI study suggests

Scientists discover link between Huntington's disease and dysfunction of subthalamic nucleus

Music may regulate mood, emotional responses at behavioral and neuronal level

Researchers find accumulation of tumor suppressor in liver after food withdrawal

Fly study shows RNA pathway plays major role in normal health and longevity

Research sheds new light on key drivers of cancer metastasis

Researchers engineer promising live-attenuated RSV vaccine candidate

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research