Gene News and Research

Latest Gene News and Research

Scientists engineer smallest CRISPR-Cas9 system to date

Scientists at the Center for Genome Engineering, within the Institute for Basic Science0, in collaboration with KIM Eunji and KIM Jeong Hun have engineered the smallest CRISPR-Cas9 to date, delivered it to the muscle cells and in the eyes of mice via adeno-associated viruses and used it to modify a gene causing blindness.

21 Feb 2017

High levels of biomarker linked to poor prognosis in African-Americans with triple-negative breast cancer

Having high levels of a certain biomarker is linked to poor prognosis in African-American patients with triple-negative breast cancer, while the same biomarker doesn't influence disease outcomes in white patients, according to a new study.

21 Feb 2017

microDimensions launches new version of high precision whole slide alignment software

microDimensions launches a new version of its high precision whole slide alignment software Slidematch. With the new version users can align digital whole slide images from consecutive sections in brightfield and fluorescence mode, e.g. for the evaluation of the HER2 status of cancer patients.

From microDimensions - Bramlage Scientific GmbH 21 Feb 2017

Targeting tumor suppressor protein could be effective treatment for some AML patients, study suggests

Researchers in Germany have discovered that a tumor suppressor protein thought to prevent acute myeloid leukemia (AML) can actually promote a particularly deadly form of the disease.

17 Feb 2017

New imaging technology catches DNA naturally fluorescing

Many of the secrets of cancer and other diseases lie in the cell's nucleus. But getting way down to that level -- to see and investigate the important genetic material housed there -- requires creative thinking and extremely powerful imaging techniques.

17 Feb 2017

Mice study provides clues to how genetic variations in gut microbes influence metabolic disease

The community of microorganisms that resides in the gut, known as the microbiome, has been shown to work in tandem with the genes of a host organism to regulate insulin secretion, a key variable in the onset of the metabolic disease diabetes.

17 Feb 2017

UTMB researchers unravel mystery of how Zika virus causes birth defects

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered the mechanisms that the Zika virus uses to alter brain development. These findings are detailed in Stem Cell Reports.

17 Feb 2017

Researchers provide insight into causes of left or right-handedness

A preference for the left or the right hand might be traced back to that asymmetry. "These results fundamentally change our understanding of the cause of hemispheric asymmetries," conclude the authors. The team report about their study in the journal eLife.

17 Feb 2017

MRC researchers discover genetic 'switch' that plays key role in Parkinson's disease

A genetic 'switch' has been discovered by MRC researchers at the University of Leicester which could help to prevent or delay the symptoms of Parkinson's disease.

17 Feb 2017

DNAstack provides key support to strengthen global Internet of Genomics

Even though 60% of the global population resides in the African and Asian continents, only a small portion of these genomes have been sequenced, representing less than 0.2% of data currently collected. There are more than 4 billion people who are not represented well with the current genome sequencing efforts.

17 Feb 2017

Scientists map vast spider web of cancer proteins to reveal new drug targets

Scientists at Winship Cancer Institute of Emory University have mapped a vast spider web of interactions between proteins in lung cancer cells, as part of an effort to reach what was considered "undruggable."

17 Feb 2017

New method that detects NMD efficiency could help in treatment of many diseases

In cells, DNA is first converted to RNA, and RNA is next converted to proteins--a complicated process involving several other steps. Nonsense-mediated RNA decay is a processing pathway in cells that, like a broom, cleans up erroneous RNA to prevent its productive conversion into an aberrant protein, which could lead to disease.

17 Feb 2017

UT Southwestern scientists unravel role of PARP enzymes in major cellular activities

A component of an enzyme family linked to DNA repair, stress responses, and cancer also plays a role in enhancing or inhibiting major cellular activities under physiological conditions, new research shows.

16 Feb 2017

Discovery of 'molecular switch' could lead to effective new treatments for auto-immune diseases

The discovery of the 'molecular switch' that causes inflammatory bowel disease (IBD) and Celiac disease, could lead to more effective new treatments for these life-changing auto-immune conditions, according to research from scientists at King's College London and University College London.

16 Feb 2017

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

The Helmholtz Zentrum München has published results of the largest genome-wide association study on proteomics to date.

16 Feb 2017

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

Genomic testing of biopsies from patients with deadly, treatment-resistant cancerous blood syndromes called histiocytoses allowed doctors to identify genes fueling the ailments and use targeted molecular drugs to successfully treat them.

16 Feb 2017

HMS scientists listen to crosstalk between gut microbes and immune system

The human gut is home to some 100 trillion bacteria, comprising between 250 and 500 species. This astounding array of organisms, collectively known as the gut microbiome, is a powerful regulator of disease and health and has been implicated in conditions ranging from inflammatory bowel disease to multiple sclerosis.

16 Feb 2017

Glowing mice could mark major step forward for new gene therapy

Timothy Blake, a postdoctoral fellow in the Waymouth lab, was hard at work on a fantastical interdisciplinary experiment. He and his fellow researchers were refining compounds that would carry instructions for assembling the protein that makes fireflies light up and deliver them into the cells of an anesthetized mouse. If their technique worked, the mouse would glow in the dark.

16 Feb 2017

Canadian researchers use gene therapy to treat patient with Fabry disease

A team of Canadian physicians and researchers is believed to be the first in the world to have used gene therapy to treat a patient with Fabry disease, a rare inherited enzyme deficiency that can damage major organs and shorten lifespan.

16 Feb 2017

UAB researchers show how GARP2 protein accelerates retinal degeneration in mice

In the retina of the eye, rod and cone cells turn light into electrical signals, the first step toward human vision.

16 Feb 2017

Gene News and Research

Latest Gene News and Research

Scientists engineer smallest CRISPR-Cas9 system to date

High levels of biomarker linked to poor prognosis in African-Americans with triple-negative breast cancer

microDimensions launches new version of high precision whole slide alignment software

Targeting tumor suppressor protein could be effective treatment for some AML patients, study suggests

New imaging technology catches DNA naturally fluorescing

Mice study provides clues to how genetic variations in gut microbes influence metabolic disease

UTMB researchers unravel mystery of how Zika virus causes birth defects

Researchers provide insight into causes of left or right-handedness

MRC researchers discover genetic 'switch' that plays key role in Parkinson's disease

DNAstack provides key support to strengthen global Internet of Genomics

Scientists map vast spider web of cancer proteins to reveal new drug targets

New method that detects NMD efficiency could help in treatment of many diseases

UT Southwestern scientists unravel role of PARP enzymes in major cellular activities

Discovery of 'molecular switch' could lead to effective new treatments for auto-immune diseases

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

Doctors use targeted molecular drugs to treat fatal cancerous blood syndromes

HMS scientists listen to crosstalk between gut microbes and immune system

Glowing mice could mark major step forward for new gene therapy

Canadian researchers use gene therapy to treat patient with Fabry disease

UAB researchers show how GARP2 protein accelerates retinal degeneration in mice

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)