Gene News and Research

Latest Gene News and Research

Study opens up possibility of developing potential hormone therapies for SSc skin disease

The results of a study presented today at the European League Against Rheumatism Annual Congress showed for the first time a beneficial effect of oestrogens in experimental models of skin fibrosis that are representative of the disease process in systemic sclerosis (SSc).

13 Jun 2016

Defects in cerebrospinal fluid flow may contribute to scoliosis during adolescence

A new study in zebrafish suggests that irregular fluid flow through the spinal column brought on by gene mutations is linked to a type of scoliosis that can affect humans during adolescence.

13 Jun 2016

Findings may help explain why rheumatoid arthritis drugs vary in effect

Researchers at the University of California San Diego School of Medicine, with colleagues in Pennsylvania and China, report that not only are there distinct differences in key cellular processes and molecular signatures between rheumatoid arthritis (RA) and osteoarthritis (OA) but, more surprisingly, there are joint-specific differences in RA.

12 Jun 2016

About 30% of iPSCs not safe for clinical use, report multi-institutional researchers

As the promise of using regenerative stem cell therapies draws closer, a consortium of biomedical scientists reports about 30 percent of induced pluripotent stem cells they analyzed from 10 research institutions were genetically unstable and not safe for clinical use.

10 Jun 2016

Carfilzomib therapy shows promise for pre-kidney transplant patients

Early findings by researchers at the University of Cincinnati College of Medicine suggest that the use of a second generation cancer drug, carfilzomib, may provide an improved approach for the reduction of antibodies in potential kidney transplant candidates.

10 Jun 2016

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors.

10 Jun 2016

Lack of signaling protein CXCR4 may halt cancer development

Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties.

10 Jun 2016

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

Scientists discover new ZBTB7A gene mutation that promotes growth of cancer cells

Biomarkers play an important role in modern cancer medicine. They are used as tools to diagnose cancers more precisely and to better predict the course of the disease.

10 Jun 2016

Researchers receive $2.4 million grant to study effects of parenting on behavior of adolescents with FXS

University of Kansas researchers have been awarded a five-year, $2.4 million grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development to study the effects of parenting on the development and behavior of adolescents with Fragile X syndrome, a single-gene disorder that is the most common cause of inherited developmental disability and the leading genetic cause of autism.

9 Jun 2016

UCLA scientists develop statistical method for conducting survival analysis of cancer patients

People with cancer are often told by their doctors approximately how long they have to live, and how well they will respond to treatments, but what if there were a way to improve the accuracy of doctors' predictions?

9 Jun 2016

Study provides insights into new pathways to generate universal vaccine against influenza viruses

Diverse antibodies induced in humans by vaccination with an avian influenza virus vaccine may offer broader, more durable protection against multiple strains of influenza than today's vaccines typically provide, according to a study led by Florian Krammer, PhD, Assistant Professor in the Department of Microbiology at the Icahn School of Medicine at Mount Sinai, and Patrick Wilson, PhD, Associate Professor in the Department of Medicine at the University of Chicago.

9 Jun 2016

Whole-exome sequencing can help characterize genetic alterations for commonly used bladder cancer cell lines

Much of basic cancer research is based on studies with cultured cancer cells. However, the usefulness of these studies greatly depends on how accurately these cancer cells grown in a dish represent human tumors.

9 Jun 2016

New drug for chronic migraine may reduce headache hours in few days

A new drug to prevent migraine was associated with fewer headache hours for people with chronic migraine within three to seven days after the first injection, according to a study published in the June 8, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Jun 2016

Gene News and Research

Latest Gene News and Research

Study opens up possibility of developing potential hormone therapies for SSc skin disease

Defects in cerebrospinal fluid flow may contribute to scoliosis during adolescence

Findings may help explain why rheumatoid arthritis drugs vary in effect

About 30% of iPSCs not safe for clinical use, report multi-institutional researchers

Carfilzomib therapy shows promise for pre-kidney transplant patients

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Lack of signaling protein CXCR4 may halt cancer development

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

Scientists discover new ZBTB7A gene mutation that promotes growth of cancer cells

Researchers receive $2.4 million grant to study effects of parenting on behavior of adolescents with FXS

UCLA scientists develop statistical method for conducting survival analysis of cancer patients

Study provides insights into new pathways to generate universal vaccine against influenza viruses

Whole-exome sequencing can help characterize genetic alterations for commonly used bladder cancer cell lines

New drug for chronic migraine may reduce headache hours in few days

Age may play major role in cell's ability to respond to physical exercise

Migraine drug has quick onset of action

New technology can detect KRAS gene mutations, facilitate targeted therapies for lung and colorectal cancers

B lymphocytes can influence psoriasis by regulating cytokine IL-10

Genetic variation may predispose certain Asian-Americans to food addiction

Lund researchers discover two new types of childhood leukaemia

eBook: Using iPSCs models for human disease research and drug discovery eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research