Gene News and Research

Latest Gene News and Research

Virologists demonstrate how poxviruses defeat the body's host immune defenses

Smallpox virus, which killed millions of humans through the ages, ranks among the world's most feared bioterrorism agents. Human monkeypox continues to occur sporadically in remote African villages.

11 Dec 2015

Shank3 gene linked to both autism and schizophrenia

Although it is known that psychiatric disorders have a strong genetic component, untangling the web of genes contributing to each disease is a daunting task. Scientists have found hundreds of genes that are mutated in patients with disorders such as autism, but each patient usually has only a handful of these variations.

10 Dec 2015

Videregen-led TETRA consortium awarded EUR 6.8 million for pivotal Phase II trial of replacement trachea

The pan-European TETRA consortium, led by Videregen Limited, has been awarded EUR 6.8 million under the Horizon 2020 programme for a pivotal Phase II clinical trial of the company's tissue engineered replacement trachea.

10 Dec 2015

Circuit awarded contract to pursue optogenetic therapies for peripheral nervous system indications

Circuit Therapeutics today announced that it has been awarded a 2.7 million dollar contract from the Defense Advanced Research Projects Agency to pursue optogenetic therapies for peripheral nervous system indications. The award, part of DARPA's Electrical Prescriptions (ElectRX) program, will enable Circuit to pursue research and development projects related to its treatment for neuropathic pain.

10 Dec 2015

Probe based qPCR assay complete solution

Integrated DNA Technologies (IDT) has introduced its latest addition to an expanding genomic applications portfolio: PrimeTime® Gene Expression Master Mix, an optimized enzyme mix for probe-based qPCR

From Integrated DNA Technologies 10 Dec 2015

Renowned experts, Nobel laureates to convene at Toulouse Onco Week to discuss latest advances in oncology

The first Toulouse Onco Week (TOW) is due to take place from 3 to 6 February 2016 at the Pierre Baudis Congess Center, Toulouse, France. This unique event will be focused on the international fight against cancer by bringing together stakeholders from around the world and presenting the latest global innovations in oncology.

10 Dec 2015

Environmental and lifestyle factors damage men's reproductive health

Environmental and lifestyle factors are damaging men's reproductive health and may be playing a large role in decreasing fertility rates in industrialized countries, a new study in Physiological Reviews reports. Socioeconomic influences and female reproductive health cannot solely be blamed for higher incidences of infertility, the study supports.

10 Dec 2015

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

Pulmonary hypertension is an umbrella term used for many conditions that all result in elevation of the pulmonary arterial pressure. Of interest, many of these completely different clinical and pathophysiological entities result in a final common pathway of vasoconstriction, micro thrombosis and vascular remodelling.

10 Dec 2015

TET proteins needed to maintain genome instability, say researchers

Members of the TET (short for ten-eleven translocation) family have been known to function as tumor suppressors for many years, but how they keep a lid on the uncontrolled cell proliferation of cancer cells had remained uncertain. Now, researchers at the La Jolla Institute for Allergy and Immunology demonstrate that TET proteins collectively constitute a major class of tumor suppressors and are required to maintain genome instability.

9 Dec 2015

Seeing alcohol abuse, drug use can make teens engage in antisocial behavior on the same day

Seeing others drink alcohol or use drugs makes it more likely that teenagers will engage in antisocial behavior on the same day, according to new findings from Duke University.

9 Dec 2015

Tetra begins human Phase 1 safety trials of BPN14770

Tetra Discovery Partners today announced that the company has initiated human Phase 1 safety trials of its lead compound BPN14770, which Tetra is developing as a potential treatment to both improve memory and slow the progression of Alzheimer's disease.

9 Dec 2015

Gene mutations that cause congenital heart disease also lead to neurodevelopmental delays

Some of the same gene mutations that cause heart defects in children also lead to neurodevelopmental delays, including learning disabilities. A large study of congenital heart disease (CHD) reveals overlapping genetic influences during early childhood development.

9 Dec 2015

Gene may play role in protecting breast cancer patients from developing chemobrain

A team of researchers from the National University of Singapore has established that variation of a gene may have a role in protecting cancer patients from developing chemotherapy-induced cognitive impairment, commonly known as 'chemofog' or 'chemobrain'.

9 Dec 2015

Providing cancer patients with counseling before and after testing for genetic mutations decreases anxiety

Many BRCA 1/2-negative patients choose to proceed with comprehensive testing for genetic mutations that increase cancer risk, and when presented with counseling before and after testing, most make informed decisions and experience decreased levels of anxiety, according to new research from the Perelman School of Medicine at the University of Pennsylvania and the Basser Center for BRCA in Penn's Abramson Cancer Center.

9 Dec 2015

Expression of particular estrogen receptor can reinstate lost memory function

The hormone estrogen helps protect memory and promote a healthy brain, but this effect wanes as women age, and even estrogen replacement therapy stops working in humans after age 65. Now researchers at University of Florida Health have used gene therapy in a rat model to show that the expression of a particular receptor can reinstate lost memory function.

9 Dec 2015

Oxitec prepares to increase supplies of OX513A to address recent outbreak of Zika virus in Brazil

Intrexon Corporation, a leader in synthetic biology, today announced that Oxitec, a UK-based subsidiary of the Company, is prepared to increase supplies of its proprietary mosquito control solution, OX513A, through its Brazil facilities to assist Brazil in addressing the recent devastating outbreak of the Zika virus and other diseases transmitted by the Aedes aegypti mosquito.

8 Dec 2015

Researchers find new significant link between NPM protein and development of AML

A team of researchers from the National University of Singapore has found a new significant correlation between the protein nucleophosmin (NPM) and the development of an aggressive form of blood cancer called acute myeloid leukemia (AML).

8 Dec 2015

Existing compound offers hope for slowing Huntington's disease progression

Currently, there is no treatment to halt the progression of Huntington's disease (HD), a fatal genetic disorder that slowly robs sufferers of their physical and mental abilities. Now, researchers at University of California, San Diego School of Medicine have discovered that an existing compound, previously tested for diabetes, offers hope for slowing HD and its symptoms.

8 Dec 2015

Plasmacytoid dendritic cells may not contribute to late-stage lupus

For years, biomedical researchers have suspected that a specific set of immune cells are responsible for causing disease in lupus patients, but until now they haven't known for sure one way or the other.

8 Dec 2015

CTTV launches new web platform for identifying therapeutic targets

The Centre for Therapeutic Target Validation (CTTV) has launched a new web platform for life-science researchers that helps them identify therapeutic targets for new and repurposed medicines. Today's launch underscores the CTTV's commitment to share its data openly to benefit the broader scientific community.

8 Dec 2015

Gene News and Research

Latest Gene News and Research

Virologists demonstrate how poxviruses defeat the body's host immune defenses

Shank3 gene linked to both autism and schizophrenia

Videregen-led TETRA consortium awarded EUR 6.8 million for pivotal Phase II trial of replacement trachea

Circuit awarded contract to pursue optogenetic therapies for peripheral nervous system indications

Probe based qPCR assay complete solution

Renowned experts, Nobel laureates to convene at Toulouse Onco Week to discuss latest advances in oncology

Environmental and lifestyle factors damage men's reproductive health

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

TET proteins needed to maintain genome instability, say researchers

Seeing alcohol abuse, drug use can make teens engage in antisocial behavior on the same day

Tetra begins human Phase 1 safety trials of BPN14770

Gene mutations that cause congenital heart disease also lead to neurodevelopmental delays

Gene may play role in protecting breast cancer patients from developing chemobrain

Providing cancer patients with counseling before and after testing for genetic mutations decreases anxiety

Expression of particular estrogen receptor can reinstate lost memory function

Oxitec prepares to increase supplies of OX513A to address recent outbreak of Zika virus in Brazil

Researchers find new significant link between NPM protein and development of AML

Existing compound offers hope for slowing Huntington's disease progression

Plasmacytoid dendritic cells may not contribute to late-stage lupus

CTTV launches new web platform for identifying therapeutic targets

eBook: Using iPSCs models for human disease research and drug discovery eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich