Genetics News and Research

Latest Genetics News and Research

Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China

Cornelia de Lange syndrome (CdLS) is a rare genetic disorder with symptoms, including facial anomalies (such as fused eyebrows, short nose, upturned nose tip, and downturned mouth corners), growth retardation, small head (microcephaly), developmental delays, cognitive impairments, excess hair growth, and limb anomalies.

29 Aug 2025

New off-the-shelf immunotherapy for metastatic kidney cancer could help improve outcomes

UCLA researchers have developed a new kind of immunotherapy that uses specially engineered immune cells equipped with built-in weapons to attack kidney cancer tumors and reprogram their protective environment - all without the need to customize treatment for each individual patient.

29 Aug 2025

Proteomic study reveals new drug targets in gastric signet ring cell carcinoma

Gastric signet ring cell carcinoma (GSRCC) is a distinct subtype of gastric cancer (GC) with unique epidemiological and pathogenic characteristics.

29 Aug 2025

Inherited DNA changes can cause hormone imbalance in women with polycystic ovary syndrome

Increased testosterone levels are a consistent hormonal abnormality in women with polycystic ovary syndrome (PCOS). This study identified specific DNA variants in the gene DENND1A, which increase testosterone production in PCOS.

29 Aug 2025

Gut disorders forecast Alzheimer’s and Parkinson’s risk years before diagnosis

Study maps clinical, genetic, and proteomic links between gut-brain disorders and neurodegeneration, showing how diabetes, vitamin D deficiency, and bowel disorders forecast Alzheimer’s and Parkinson’s years in advance. Multimodal models in biobanks highlight early detection and personalized prevention opportunities.

28 Aug 2025

Research sheds new light on depression’s biological roots

Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are altered in people with depression.

28 Aug 2025

AI and routine lab tests offer a more accurate prediction of genetic disease risk

When genetic testing reveals a rare DNA mutation, doctors and patients are frequently left in the dark about what it actually means.

28 Aug 2025

COPD care pathways improve hospital outcomes and standardize treatment

Using a care pathway focused on chronic obstructive pulmonary disease (COPD) can lead to shorter hospital stays, increased referrals to pulmonary rehabilitation, and improved standardization of care, according to a new study.

28 Aug 2025

Killifish study reveals multi-generational impacts of exposure to crude oil and flame retardants

A tiny fish with transparent embryos is helping University of California, Davis, researchers shed light on how exposure to crude oil and flame retardants can affect behavior, skeletal growth, cardiac health and other internal functions in offspring and subsequent generations.

28 Aug 2025

Older age and low fitness identified as independent risk factors for heart rhythm disorders

New research has revealed that older age and low aerobic fitness levels are strong and independent risk factors for a high burden of heartbeat irregularities, known as arrhythmias, that indicate future cardiovascular risk.

27 Aug 2025

Multi-analyte test accurately identifies brain cancers using cerebrospinal fluid

A novel, multi-analyte test developed by researchers at the Johns Hopkins Kimmel Cancer Center, its Ludwig Center and the Johns Hopkins Department of Neurosurgery can accurately identify brain cancers using small samples of cerebrospinal fluid (CSF), offering a promising new tool to guide clinical decision-making.

27 Aug 2025

Using cannabis to self medicate linked to higher risk of paranoia

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London, in partnership with the University of Bath, has found that the reasons why a person chooses to use cannabis can increase their risk of developing paranoia.

27 Aug 2025

Yale scientists boost mRNA vaccine power with new technology

Messenger RNA, or mRNA, vaccines entered the public consciousness when they were introduced during the COVID-19 pandemic, and both Pfizer-BioNTech and Moderna used the technology in developing their highly effective vaccines to fight the virus.

27 Aug 2025

Mediterranean diet lowers dementia risk by altering key metabolites

Researchers linked genetics, plasma metabolites, and Mediterranean diet adherence to dementia risk in two large US cohorts, showing APOE4 homozygotes had distinct metabolic pathways. Diet-related metabolites mediated protection, highlighting precision-prevention opportunities.

26 Aug 2025

Genetic variants mimicking IL-6 inhibition linked to lower cardiovascular risk

People with lower interleukin-6 activity have a reduced risk of cardiovascular diseases, a new LMU study reveals.

26 Aug 2025

Vesalius: Harnessing artificial intelligence to decode cancer tissue architecture

Researchers at VCU Massey Comprehensive Cancer Center have developed a new computational tool called Vesalius, which could help clinicians understand the complex relationships between cancer cells and their surrounding cells, leading to potential discoveries regarding the development of hard-to-treat cancers.

26 Aug 2025

Genetics News and Research

Latest Genetics News and Research

Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China

New off-the-shelf immunotherapy for metastatic kidney cancer could help improve outcomes

Proteomic study reveals new drug targets in gastric signet ring cell carcinoma

Inherited DNA changes can cause hormone imbalance in women with polycystic ovary syndrome

Gut disorders forecast Alzheimer’s and Parkinson’s risk years before diagnosis

Research sheds new light on depression’s biological roots

AI and routine lab tests offer a more accurate prediction of genetic disease risk

COPD care pathways improve hospital outcomes and standardize treatment

Killifish study reveals multi-generational impacts of exposure to crude oil and flame retardants

Older age and low fitness identified as independent risk factors for heart rhythm disorders

Multi-analyte test accurately identifies brain cancers using cerebrospinal fluid

Using cannabis to self medicate linked to higher risk of paranoia

Yale scientists boost mRNA vaccine power with new technology

Mediterranean diet lowers dementia risk by altering key metabolites

Genetic variants mimicking IL-6 inhibition linked to lower cardiovascular risk

Vesalius: Harnessing artificial intelligence to decode cancer tissue architecture

Mitochondria fight infection by starving parasites of essential nutrients

People with schizophrenia are more likely to develop COPD

Genetics and diet work together to shape daily rhythms of fat metabolism

Mediterranean-style diet may reduce dementia risk in individuals with high genetic risk

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging