Genetics News and Research

Latest Genetics News and Research

Genetic markers show promise in predicting mood disorder treatment outcomes

In a comprehensive Genomic Press Thought Leaders Invited Review, researchers have synthesized findings from dozens of studies examining how genetic markers for mood disorders influence treatment outcomes and clinical features across major psychiatric conditions.

24 Jun 2025

New genomic test predicts chemotherapy resistance in cancer patients

Chemotherapy seeks to destroy tumor cells and has been a standard treatment for cancer for decades.

24 Jun 2025

New DNA test predicts chemotherapy resistance in cancer patients

Cancer Research UK-funded scientists at the University of Cambridge, in collaboration with the Spanish National Cancer Research Centre (CNIO) and Cambridge-based startup Tailor Bio, have created a test which can successfully predict whether cancer will resist common forms of chemotherapy treatment.

23 Jun 2025

Men lose more weight than women on the keto diet, new study reveals why

Men lose more weight than women on a ketogenic diet, according to a comprehensive review in Frontiers in Nutrition. Sex differences in hormones, metabolism, and fat distribution influence the effectiveness of the ketogenic diet for obesity.

22 Jun 2025

Researchers find unique genetic profile in childhood cancer survivors with cardiomyopathy

Scientists at St. Jude Children’s Research Hospital studied how common and rare genetic variants influence late-onset cardiomyopathy risk, highlighting the unique genetic complexity of childhood cancer survivors.

20 Jun 2025

Scientists develop tool to predict bowel cancer drug resistance

Scientists have developed a tool that can predict how bowel cancer adapts to treatment – helping researchers to design new personalized drugs that will keep patients living well for longer.

20 Jun 2025

Transfer RNA-derived small RNAs transform the landscape of liquid biopsy

A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of diseases, particularly cancers.

20 Jun 2025

Exploring the intricate epigenetic regulatory network of lncRNAs in hepatocellular carcinoma

A new review published in Genes & Diseases explores the intricate epigenetic regulatory network of long noncoding RNAs (lncRNAs) in hepatocellular carcinoma (HCC), shedding light on the profound impact of DNA methylation, histone modifications, RNA methylation, and microRNAs on lncRNA transcription.

20 Jun 2025

Inflammation and immune dysregulation drive breast cancer in aging women

Age-related and postmenopausal breast cancer progression remains a significant challenge, with growing evidence pointing to the role of pro-inflammatory cytokines and CXC chemokines in tumor development and immune system modulation.

20 Jun 2025

Targeting IGF2BP1 offers a new approach to cancer therapy

The RNA-binding protein IGF2BP1 has emerged as a key regulator of cancer hallmarks, influencing tumor proliferation, metastasis, immune evasion, and resistance to cell death.

20 Jun 2025

Fibroblast Growth Factor 8 drives key processes in embryonic development

The role of Fibroblast Growth Factor 8 (FGF8) in embryonic development and organ formation is gaining increased recognition as scientists uncover its wide-ranging influence.

20 Jun 2025

Circular RNAs emerge as key players in hepatitis B-related liver cancer

Hepatitis B virus-induced hepatocellular carcinoma (HCC) remains a major global health burden, and new therapeutic and diagnostic approaches are urgently needed.

20 Jun 2025

Why Alzheimer’s DNA tests don’t treat all populations equally

A major global study tested whether European-derived polygenic risk scores (PGS) for Alzheimer’s disease can predict risk across diverse populations. While PGS performed well in many groups, it was less accurate in individuals of sub-Saharan African and Indian ancestry, highlighting the urgent need for more inclusive genetic data.

19 Jun 2025

Researchers identify key differences in Alzheimer's progression in humans and animal models

Although it is known that Alzheimer's disease can start up to 20 years before the first symptoms appear, the lack of knowledge about how it progresses prevents the development of effective treatments, as well as a clear diagnosis to confront this neurodegenerative disease, which origin is also unknown.

19 Jun 2025

Understanding the interconnected roles of microbial, metabolic, and immune biomarkers in IBD

Inflammatory Bowel Disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory condition of the gastrointestinal tract with a rising global burden.

19 Jun 2025

Scientists find hundreds of genes that behave like light switches

Gene expression, where cells use the genetic information encoded in DNA to produce proteins, has been thought of as a dimmer light.

19 Jun 2025

New gene therapy strategy reactivates dormant genes to treat blood disorders

Researchers have found a promising new method for gene therapy. They successfully restarted inactive genes by bringing them closer to genetic switches on the DNA called enhancers.

19 Jun 2025

Early infant behavior predicts cognitive ability decades later

Watching a baby babble, play and interact with others can provide useful insight into what their cognitive ability might be like decades later, according to new University of Colorado Boulder research published in the journal PNAS.

19 Jun 2025

Utah State biologist investigates chromosomal changes driving evolution

How do living things evolve? What is the myriad of processes by which generic variations in a population affect organisms' survival and allow reproduction in an ever-changing environment?

19 Jun 2025

What matters more for diabetes risk: lifestyle or body weight?

A large, multi-ethnic US cohort study found that combining healthy lifestyle factors—non-smoking, regular physical activity, a healthy diet, and moderate alcohol consumption into a Lifestyle Risk Factor Index (LSRI) was linked to a significantly lower risk of type 2 diabetes. However, BMI was a stronger predictor of diabetes risk, and the impact of lifestyle varied across ethnic groups.

18 Jun 2025