Genetics News and Research

Latest Genetics News and Research

MGI Tech joins forces with SAMRC and DSTI to launch South Africa’s 110K Human Genome Program and unveil Africa’s first DNBSEQ-T7, ushering in a new era in African genomics

The DNBSEQ-T7 sequencing platform and 110K Human Genome Program are transforming South Africa's genomic landscape, promoting local expertise and health equity.

From MGI 11 Nov 2025

Daily oral medication matches injectable therapies in reducing bad cholesterol

Among people with a previous heart attack or stroke, or who are at high risk for one, a daily oral medication may offer an effective alternative to injections of PCSK9 inhibitors to lower low-density lipoprotein (LDL or "bad" cholesterol), according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Can your gut bacteria predict your age and lifestyle? New study says yes

Researchers used a new covariance-based method, MANOCCA, to map how environmental factors like age, sex, smoking, and BMI shape bacterial co-abundance in the healthy gut microbiome. The study revealed that key microbial interactions cluster in a few core families and that MANOCCA predicts host traits more accurately than standard models.

9 Nov 2025

Rockefeller scientists engineer next-generation antibody to replace IVIG therapy

Intravenous immunoglobulin (IVIG) therapy involves infusing patients with naturally occurring IgG antibodies to treat autoimmune conditions.

7 Nov 2025

Study reveals structural and cellular clues behind cancer-linked GnT-V enzyme selectivity

Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection.

7 Nov 2025

Study reveals tumor defense mechanisms in colorectal cancer

Colorectal cancer is one of the leading causes of cancer death worldwide. In recent years, immunotherapies-treatments that reactivate the immune system to attack tumor cells-have transformed the treatment of many types of cancer.

7 Nov 2025

Researchers refine tools to map DNA’s 3D structure inside cells

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the code itself, but how it's arranged in space.

6 Nov 2025

Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections

Lowering the transcription factor PU.1 reprograms microglia into a neuroprotective, lymphoid-like state that compacts amyloid, blocks tau spread, and preserves synapses in Alzheimer’s disease. Microglial CD28 signaling helps restrain inflammation, revealing a regulatory switch that may inform future immunotherapies targeting microglia rather than neurons.

6 Nov 2025

Two main methods for discovering disease genes reveal distinct aspects of biology

The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While both methods are widely used, the research found that they identify different genes, with major implications for drug development.

6 Nov 2025

Oxidative stress linked to repetitive behaviors in mice

Abnormal repetitive behaviors in mice are strongly linked to multiple biomarkers of oxidative stress, which occurs when antioxidants cannot counteract the effects of harmful molecules in the body, according to a study published November 5, 2025, in the open-access journal PLOS One by Kendall Coden and Dr. Joseph Garner of Stanford University, U.S.

5 Nov 2025

Newly identified microglia subtype offers protection against Alzheimer’s disease

In Alzheimer's disease, the leading cause of dementia, microglia-the brain's immune defenders-can act as both protectors and aggressors, shaping how the disease progresses.

5 Nov 2025

Radiotherapy may be unnecessary for many breast cancer patients after mastectomy

Radiotherapy can be safely omitted as a treatment for many breast cancer patients who have had a mastectomy and are taking anti-cancer drugs, a study shows.

5 Nov 2025

Bowel cancer’s “Big Bang” moment reveals how the disease takes shape

Like the astronomical explosion that kickstarted the universe, bowel cancer has a "Big Bang" moment which determines how it will grow, according to new research from Cancer Research UK and Wellcome Trust-funded scientists.

5 Nov 2025

Do gut microbes cause autism? New research says diet plays the bigger role

In a family-based study, researchers found that children with autism spectrum disorder (ASD) shared similar gut microbiomes with their relatives but showed distinctly different eating habits. Their preference for sweets and limited vegetable intake suggests behavior-driven dietary choices may influence, rather than result from, microbiome differences.

5 Nov 2025

PTGES3 emerges as key regulator of androgen receptor in prostate cancer

A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player in prostate cancer.

5 Nov 2025

Japanese study finds widespread reluctance to donate cells for brain organoid research

Research on human brain organoids (HBOs) is directly challenging how biobanks and biomedical institutes recruit volunteers.

4 Nov 2025

USC researchers map genetic architecture of the human corpus callosum

For the first time, a research team led by the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has mapped the genetic architecture of a crucial part of the human brain known as the corpus callosum-the thick band of nerve fibers that connects the brain's left and right hemispheres.

4 Nov 2025

Over one-third of men would rather endure stressful situations than discuss prostate health

A new survey from Orlando Health reveals that over one-third of men (38%) would rather endure stressful situations, such as watching their team lose a big game or being stuck in traffic, than discuss their prostate health.

4 Nov 2025

Stress hormones may silence crucial neuronal genes through specific RNA molecules

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

4 Nov 2025

Combined analysis of three blood tests enhances heart attack risk prediction

A combined analysis of blood tests to measure three biomarkers linked to higher risk of cardiovascular disease-lipoprotein a (Lp(a)), remnant cholesterol and high-sensitivity C-reactive protein (hsCRP)-may help identify high-risk individuals earlier and guide more personalized prevention strategies, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Genetics News and Research

Latest Genetics News and Research

MGI Tech joins forces with SAMRC and DSTI to launch South Africa’s 110K Human Genome Program and unveil Africa’s first DNBSEQ-T7, ushering in a new era in African genomics

Daily oral medication matches injectable therapies in reducing bad cholesterol

Can your gut bacteria predict your age and lifestyle? New study says yes

Rockefeller scientists engineer next-generation antibody to replace IVIG therapy

Study reveals structural and cellular clues behind cancer-linked GnT-V enzyme selectivity

Study reveals tumor defense mechanisms in colorectal cancer

Researchers refine tools to map DNA’s 3D structure inside cells

Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections

Two main methods for discovering disease genes reveal distinct aspects of biology

Oxidative stress linked to repetitive behaviors in mice

Newly identified microglia subtype offers protection against Alzheimer’s disease

Radiotherapy may be unnecessary for many breast cancer patients after mastectomy

Bowel cancer’s “Big Bang” moment reveals how the disease takes shape

Do gut microbes cause autism? New research says diet plays the bigger role

PTGES3 emerges as key regulator of androgen receptor in prostate cancer

Japanese study finds widespread reluctance to donate cells for brain organoid research

USC researchers map genetic architecture of the human corpus callosum

Over one-third of men would rather endure stressful situations than discuss prostate health

Stress hormones may silence crucial neuronal genes through specific RNA molecules

Combined analysis of three blood tests enhances heart attack risk prediction

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