Genetics News and Research

Latest Genetics News and Research

Researchers discover two new gene regions connected to bipolar disorder

First on top of the world and then in the depths of despair - this is what the extreme mood changes for people with bipolar disorder are like. Under the direction of scientists from Bonn, Mannheim and Basel, an international collaboration of researchers discovered two new gene regions that are connected to the prevalent disease. In addition, they were able to confirm three additional suspect genes.

11 Mar 2014

First Edition: March 11, 2014

Today's headlines include reports that the Centers for Medicare & Medicaid Services is stepping back from proposed changes to the Medicare drug program.

11 Mar 2014

Bayer and Onyx announce Phase 3 trial evaluating use of NEXAVAR for patients with HCC after local ablation

Bayer HealthCare Pharmaceuticals Inc. and Onyx Pharmaceuticals, Inc., an Amgen subsidiary (Nasdaq: AMGN), today announced that a Phase 3 trial evaluating the investigational use of NEXAVAR® (sorafenib) tablets as an adjuvant treatment for patients with hepatocellular carcinoma (HCC), or liver cancer, who had no detectable disease after surgical resection or local ablation, did not meet its primary endpoint of improving recurrence-free survival.

11 Mar 2014

Genetics may explain why some athletes are high functioning despite having hip abnormalities

Genetics may explain why some senior athletes are high functioning despite having one or both hip abnormalities typically associated with early onset osteoarthritis (OA): developmental dislocation of the hip (dysplasia), a loose hip joint; or femoroacetabular impingement (FAI), a condition in which the hip bones are abnormally shaped, according to new research presented today at the 2014 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).

11 Mar 2014

Singapore's largest institute launched to improve treatment for stroke, Parkinson disease

The National Neuroscience Research Institute Singapore - a joint venture by the National Neuroscience Institute and Duke-NUS Graduate Medical School - has been launched to improve treatment and seek cures through research for brain and nervous system disorders such as stroke, Parkinson disease and dementia.

11 Mar 2014

Thirteen graduate students to receive 2014 Harold M. Weintraub Graduate Student Award

Thirteen graduate students from institutes throughout North America have been chosen to receive the 2014 Harold M. Weintraub Graduate Student Award sponsored by the Basic Sciences Division of Fred Hutchinson Cancer Research Center.

11 Mar 2014

Professors receive $31M grant to establish Center for Research in Diagnostics and Discovery

W. Ian Lipkin, director of the Center for Infection and Immunity and John Snow Professor of Epidemiology at the Mailman School of Public Health, has received an award of up to $31 million over a five-year period by the National Institutes of Health (NIH) to establish the Center for Research in Diagnostics and Discovery (CRDD) under the auspices of a new National Institute of Allergy and Infectious Diseases (NIAID) program entitled Centers of Excellence for Translational Research.

11 Mar 2014

Genetic basis of hereditary disease causes severe brain atrophy in Jews of Moroccan ancestry

Ben-Gurion University of the Negev (BGU) researchers have unraveled the genetic basis of a hereditary disease that causes severe brain atrophy, mental retardation and epilepsy in Jews of Moroccan ancestry, according to a study published this week online in the Journal of Medical Genetics.

11 Mar 2014

Homologous recombination technology for research applications in genetically modified rodents: an interview with Alexandre Fraichard, CEO, genOway

Homologous recombination is a technology that enables the targeted insertion of nucleotide fragments into the genome of a cell. It is called ‘homologous’ because it uses a sequence that is a homologue to the sequence being targeted in a gene, so that the sequence is recognized.

10 Mar 2014

Harvard Review of Psychiatry provides updates on ASD research

Recent years have seen exciting progress in key areas of research on autism spectrum disorders (ASD): from possible genetic causes, to effective treatments for common symptoms and clinical problems, to promoting success for young people with ASD entering college. Updates on these and other advances in ASD research are presented in the March special issue of Harvard Review of Psychiatry.

10 Mar 2014

Proteus Digital Health teams up with leading organisations to bring digital health technology to the UK

Leading digital medicines company Proteus Digital Health is partnering with Eastern Academic Health Science Network, The Northern Health Science Alliance and Oxford University, Oxford University Hospitals NHS Trust and Oxford Academic Health Science Network to bring digital health technology and global operations and manufacturing to the UK.

10 Mar 2014

Researchers find that protein synthesis can be studied in adult stem cells

For the first time, researchers have shown that an essential biological process known as protein synthesis can be studied in adult stem cells - something scientists have long struggled to accomplish. The groundbreaking findings from the Children's Medical Center Research Institute at UT Southwestern (CRI) also demonstrate that the precise amount of protein produced by blood-forming stem cells is crucial to their function.

10 Mar 2014

New theory regarding cause and development of endometriosis

Changes to two previously unstudied genes are the centerpiece of a new theory regarding the cause and development of endometriosis, a chronic and painful disease affecting 1 in 10 women.

10 Mar 2014

Edison Pharmaceuticals initiates Phase 2B/3 study of EPI-743 in children with Leigh syndrome

Edison Pharmaceuticals today announced the initiation of a phase 2B/3 study entitled, "A Phase 2B/3 Open-label Study of EPI-743 in Children with Leigh Syndrome" to be conducted in conjunction with Dainippon Sumitomo Pharma Co, Ltd.

10 Mar 2014

Mutations in gene associated with leukaemia may affect growth, intellectual development in children

Mutations in a gene associated with leukaemia cause a newly described condition that affects growth and intellectual development in children, new research reports.

10 Mar 2014

People with type 2 diabetes have epigenetic changes on DNA

People with type 2 diabetes have epigenetic changes on their DNA that healthy individuals do not have. This has been shown in a major study by researchers at Lund University. The researchers also found epigenetic changes in a large number of genes that contribute to reduced insulin production.

9 Mar 2014

STSI releases Scripps Wellderly Genome Resource to explore genetic cause for certain illness

Scientists exploring the genetic causes of illnesses such as Alzheimer's disease, heart disease, cancer and diabetes now have a new tool - a reference DNA dataset built by researchers at Scripps Translational Science Institute (STSI).

7 Mar 2014

BWH researchers explore newer approaches to treat Alzheimer's disease

A team of Alzheimer's disease (AD) researchers at Brigham and Women's Hospital (BWH) has been able to study the underlying causes of AD and develop assays to test newer approaches to treatment by using stem cells derived from related family members with a genetic predisposition to (AD).

7 Mar 2014

TAZ gene represents potential target for drug therapies to treat aggressive types of breast cancer

Significance: Understanding more about how the different types of cells in breast tissue develop improves our knowledge of breast cancer. TAZ represents a potential new target for drug therapies to treat aggressive types of breast cancer.

7 Mar 2014

Ohr Pharmaceutical partners with CSHL to develop trodusquemine and related analogs

Ohr Pharmaceutical, a pharmaceutical company focused on the development of novel therapeutics for large unmet medical needs, and leading global cancer research center Cold Spring Harbor Laboratory (CSHL) today announced the establishment of DepYmed Inc., a new joint venture to develop trodusquemine and related analogs.

6 Mar 2014

Genetics News and Research

Latest Genetics News and Research

Researchers discover two new gene regions connected to bipolar disorder

First Edition: March 11, 2014

Bayer and Onyx announce Phase 3 trial evaluating use of NEXAVAR for patients with HCC after local ablation

Genetics may explain why some athletes are high functioning despite having hip abnormalities

Singapore's largest institute launched to improve treatment for stroke, Parkinson disease

Thirteen graduate students to receive 2014 Harold M. Weintraub Graduate Student Award

Professors receive $31M grant to establish Center for Research in Diagnostics and Discovery

Genetic basis of hereditary disease causes severe brain atrophy in Jews of Moroccan ancestry

Homologous recombination technology for research applications in genetically modified rodents: an interview with Alexandre Fraichard, CEO, genOway

Harvard Review of Psychiatry provides updates on ASD research

Proteus Digital Health teams up with leading organisations to bring digital health technology to the UK

Researchers find that protein synthesis can be studied in adult stem cells

New theory regarding cause and development of endometriosis

Edison Pharmaceuticals initiates Phase 2B/3 study of EPI-743 in children with Leigh syndrome

Mutations in gene associated with leukaemia may affect growth, intellectual development in children

People with type 2 diabetes have epigenetic changes on DNA

STSI releases Scripps Wellderly Genome Resource to explore genetic cause for certain illness

BWH researchers explore newer approaches to treat Alzheimer's disease

TAZ gene represents potential target for drug therapies to treat aggressive types of breast cancer

Ohr Pharmaceutical partners with CSHL to develop trodusquemine and related analogs

Sequencing & Genomics: Elevating Science and Healthcare eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting