Genetics News and Research

Latest Genetics News and Research

Researchers demonstrate existence of an epigenetic lesion in hippocampus of Alzheimer patients

Alzheimer's disease can reach epidemic range in the coming decades, by the increasing average age of society. There are two key issues for Alzheimer's disease: there is currently no effective treatment and it has been described very few associated genetic changes (mutations) which reduces the number of targets for future therapies.

22 Jan 2014

Brain imaging via MRI scans may be useful biomarker for early detection of subtle developmental abnormalities

Researchers at Penn Medicine have generated a brain development index from MRI scans that captures the complex patterns of maturation during normal brain development.

22 Jan 2014

Experiencing family death in childhood linked with increased risk of psychosis

Experiencing a family death in childhood is associated with a small but significant increase in risk of psychosis, suggests a paper published today on bmj.com.

21 Jan 2014

Levels of depression and anxiety are higher in people with severe rheumatoid arthritis

Levels of depression and anxiety in people with severe rheumatoid arthritis are higher than previously reported, according to new research. As a result of their findings, a multi-centre team led by researchers at the Arthritis Research UK Centre for Genetics and Genomics at the University of Manchester, say that patients with severe active disease, who are waiting to go onto a biological therapy, should be routinely screened for depression by their doctors.

From The University of Manchester 21 Jan 2014

Vivaldi Biosciences inks agreement with NIAID to evaluate LAIV candidates against influenza A

Vivaldi Biosciences Inc., a clinical-stage biotechnology company developing live attenuated influenza vaccines against seasonal and pandemic influenza, today announced that it has signed a Cooperative Research and Development Agreement with the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to generate and evaluate in preclinical studies LAIV candidates against influenza A(H7N9).

21 Jan 2014

Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

Embryonal tumours with multilayered rosettes (ETMR) are rare, deadly brain tumours that affect mainly children below the age of 4 years. There are 300 cases reported but probably there are many more as this tumour is often misdiagnosed.

21 Jan 2014

Splicing factor SRSF6 promotes hyperplasia of sensitized skin

Normally, tissue injury triggers a mechanism in cells that tries to repair damaged tissue and restore the skin to a normal, or homeostatic state. Errors in this process can give rise to various problems, such as chronic inflammation, which is a known cause of certain cancers.

21 Jan 2014

Development of physical aggression in toddlers strongly linked with genetic factors

The development of physical aggression in toddlers is strongly associated genetic factors and to a lesser degree with the environment, according to a new study led by Eric Lacourse of the University of Montreal and its affiliated CHU Sainte-Justine Hospital. Lacourse's worked with the parents of identical and non-identical twins to evaluate and compare their behaviour, environment and genetics.

20 Jan 2014

Psychosis risk following childhood abuse not down to genetics

Familial risk for psychosis does not account for the association between abuse during childhood and the later development of schizophrenia, a study suggests.

20 Jan 2014

Going barefoot contributes to hookworm infections

Going barefoot in parts of Africa, Asia and South America contributes to hookworm infections, which afflict an estimated 700 million of the world's poor. The parasitic worm lives in the soil and enters the body through the feet. By feeding on victims' blood, the worms cause anemia and, in children, stunted growth and learning problems.

20 Jan 2014

EBCC-9: Most exciting breast cancer conference in Europe

The most exciting breast cancer conference in Europe, it is the only one that involves all the major players in breast cancer. The conference encourages interaction and collaboration between clinicians, scientists and patients in a partnership of equals to talk not just about scientific advances, but also the ethical, social, political, and practical issues associated with caring for patients with breast cancer. EBCC-9 is expected to attract around 5000 delegates from around 90 countries worldwide.

20 Jan 2014

Researchers discover fundamental biology of calcium waves in relation to heart arrhythmias

Researchers have discovered the fundamental biology of calcium waves in relation to heart arrhythmias. The findings published this month in the January 19 edition of Nature Medicine outlines the discovery of this fundamental physiological process that researchers hope will one day help design molecularly tailored medications that correct the pathophysiology.

20 Jan 2014

Eating high levels of flavonoids found in berries, tea, and chocolate offer protection from type 2 diabetes

Eating high levels of flavonoids including anthocyanins and other compounds (found in berries, tea, and chocolate) could offer protection from type 2 diabetes - according to research from the University of East Anglia (UEA) and King's College London.

20 Jan 2014

Research provides important new information about transmission of human leishmaniasis

Research involving scientists at the University of York has provided important new information about transmission of human leishmaniasis, a group of infectious diseases which kills more than 100,000 people a year.

18 Jan 2014

$Japanese MHLW approves ADCETRIS for relapsed or refractory CD30-positive HL and ALCL$

Japanese MHLW approves ADCETRIS for relapsed or refractory CD30-positive HL and ALCL

Seattle Genetics, Inc. today announced that its collaborator, Takeda Pharmaceutical Company Limited, has received approval of ADCETRIS (brentuximab vedotin) from the Japanese Ministry of Health, Labour and Welfare for the treatment of patients with CD30-positive relapsed or refractory Hodgkin lymphoma and anaplastic large cell lymphoma.

18 Jan 2014

Researchers managed to replicate human pancreatic beta cells in mouse model

Klaus Kaestner, PhD, professor of Genetics and postdoctoral fellow Dana Avrahami, PhD, from the Perelman School of Medicine, University of Pennsylvania, published a study this week in the Journal of Clinical Investigation, with colleague Benjamin Glaser, MD, from the Hadassah-Hebrew University Medical Center, Jerusalem, and colleagues. In this study, they were able to replicate human pancreatic beta cells - the cells in our body that produce the critical hormone insulin - in a mouse model in which donor cells were transplanted. The newly replicated cells retained features of mature beta cells and showed a physiological response to glucose.

17 Jan 2014

Gene therapies correct three forms of retinal degenerative diseases

Gene therapies developed by University of Pennsylvania School of Veterinary Medicine researchers have worked to correct different forms of blindness. While effective, the downside to these approaches to vision rescue is that each disease requires its own form of gene therapy to correct the particular genetic mutation involved, a time consuming and complex process.

17 Jan 2014

IRCM researchers show importance of DNA architecture in controlling activity of genes

A study conducted by Marie Kmita's team at the IRCM, in collaboration with Jos-e Dostie at McGill University, shows the importance of the chromatin architecture in controlling the activity of genes, especially those required for proper embryonic development.

17 Jan 2014

CSHL professor identifies two proteins that control structure of chandelier cells

Chandelier cells are neurons that use their unique shape to act like master circuit breakers in the brain's cerebral cortex. These cells have dozens, often hundreds, of branching axonal projections - output channels from the cell body of the neuron - that lend the full structure of a chandelier-like appearance.

17 Jan 2014

Atlas develops ultra-rapid point-of-care tests for a range of infectious diseases

Atlas Genetics Ltd, the diagnostic company developing ultra-rapid point-of-care (POC) tests for a range of infectious diseases, today announces that it has completed development of the Atlas io™ Reader, a POC device that can deliver laboratory quality results for molecular assays in under thirty minutes.

16 Jan 2014

Genetics News and Research

Latest Genetics News and Research

Researchers demonstrate existence of an epigenetic lesion in hippocampus of Alzheimer patients

Brain imaging via MRI scans may be useful biomarker for early detection of subtle developmental abnormalities

Experiencing family death in childhood linked with increased risk of psychosis

Levels of depression and anxiety are higher in people with severe rheumatoid arthritis

Vivaldi Biosciences inks agreement with NIAID to evaluate LAIV candidates against influenza A

Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

Splicing factor SRSF6 promotes hyperplasia of sensitized skin

Development of physical aggression in toddlers strongly linked with genetic factors

Psychosis risk following childhood abuse not down to genetics

Going barefoot contributes to hookworm infections

EBCC-9: Most exciting breast cancer conference in Europe

Researchers discover fundamental biology of calcium waves in relation to heart arrhythmias

Eating high levels of flavonoids found in berries, tea, and chocolate offer protection from type 2 diabetes

Research provides important new information about transmission of human leishmaniasis

Japanese MHLW approves ADCETRIS for relapsed or refractory CD30-positive HL and ALCL

Researchers managed to replicate human pancreatic beta cells in mouse model

Gene therapies correct three forms of retinal degenerative diseases

IRCM researchers show importance of DNA architecture in controlling activity of genes

CSHL professor identifies two proteins that control structure of chandelier cells

Atlas develops ultra-rapid point-of-care tests for a range of infectious diseases

Genetics & Genomics - Second Edition eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging