Immunology News and Research

Latest Immunology News and Research

Engineered CD40 antibody shrinks tumors and induces remission

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise-and induced great disappointment.

14 Aug 2025

COVID-19 increases risk of asthma and sinusitis while vaccination offers protection

People who have had COVID-19 are at increased risk of developing certain inflammatory diseases of the airways, such as asthma, hay fever and chronic sinusitis.

14 Aug 2025

Rare immune mutation unlocks universal antiviral protection

For a few dozen people in the world, the downside of living with a rare immune condition comes with a surprising superpower-the ability to fight off all viruses.

14 Aug 2025

Disrupting dopamine pathway stops threadworms from burrowing into the skin

Threadworms, which are a type of parasitic nematode, spend a lot of time crawling around on human skin, poking and prodding to find the best place for entry before burrowing in.

13 Aug 2025

Study investigates aging-related mechanisms in idiopathic pulmonary fibrosis using AI approaches

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease characterized by the excessive accumulation of extracellular matrix components, leading to a gradual decline in lung function and, ultimately, respiratory failure.

13 Aug 2025

mRNA vaccine shows potent efficacy in gastric cancer

Gastric cancer is one of the leading causes of cancer-related mortality worldwide, and peritoneal metastasis, wherein the cancer spreads to the peritoneum or the lining of the abdominal cavity, represents the most common form of recurrence after gastric cancer surgery.

13 Aug 2025

Researchers find CFI deficiency alarmingly high in old order Amish

Researchers from Children's Hospital of Philadelphia (CHOP) and the Clinic for Special Children found that complement factor I (CFI) deficiency, an ultra-rare genetic disorder that can cause debilitating neuroinflammation, is more than 4500 times more likely to be found in individuals of Old Order Amish ancestry than the rest of the global population.

13 Aug 2025

Natural gut molecule reverses liver damage and repairs gut lining

UC Davis Health researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure.

12 Aug 2025

Parasitic worm evades detection by suppressing skin neurons

New research, published in The Journal of Immunology, discovered that a parasitic worm suppresses neurons in the skin to evade detection.

11 Aug 2025

Understanding sex-based differences in immune system function

Many diseases affect men and women differently. Asthma tends to strike men earlier in life, yet more women develop asthma as they get older.

7 Aug 2025

New research pipeline fuels the development of universal vaccines

Most vaccines are designed to provide immunity against just one pathogen. Vaccines for chicken pox (caused by varicella-zoster virus) were only developed to fight that one disease, for example.

7 Aug 2025

Asthma drug found to prevent food allergy reactions in mice

A drug already FDA-approved for asthma was found to nearly eliminate life-threatening allergic reactions to food allergens in mice - a breakthrough that could lead to new protection for millions of people living with food allergies, reports a new Northwestern Medicine study.

7 Aug 2025

Copper oxide scaffolds show promise in treating traumatic brain injury

Traumatic brain injury (TBI) remains one of the leading causes of disability worldwide. Recent research has developed a novel electrospun scaffold loaded with copper oxide (CuO@PG), which aims to restore copper homeostasis and modulate inflammation in TBI.

7 Aug 2025

KAIST researchers link placental inflammation to childhood allergies

It is already well-known that when a mother experiences inflammation during pregnancy, her child is more likely to develop allergic diseases.

7 Aug 2025

Children show delayed exposure to respiratory viruses after COVID restrictions

COVID-19 prevention methods such as masking and social distancing also suppressed the circulation of common respiratory diseases, leaving young children lacking immunity to pathogens they otherwise would have been exposed to, a new multi-center clinical research study reveals.

6 Aug 2025

New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025