Immunology News and Research

Latest Immunology News and Research

NCI grants more than $4.2 million to launch Cancer Epitope Database and Analysis Resource

Researchers are about to welcome a new one-stop shop for crucial information on how the immune system targets cancers.

3 Jun 2021

Natural Killer cells acts as a potential target of immunotherapy, shows study

Despite a name straight from a Tarantino movie, natural killer (NK) cells are your allies when it comes to fighting infections and cancer.

2 Jun 2021

Depleting SIRPα-deficient in macrophages activate tumor antigen-specific cytotoxic T cells

In a study that will be published in Nature Communications on May 28, 2021, a research team led by Dr. Yuan Liu from Georgia State University reports that intratumoral SIRPα-deficient macrophages activate tumor antigen-specific cytotoxic T cells to eliminate various syngeneic cancers under radiotherapy.

2 Jun 2021

Study offers longitudinal roadmap of immune activation and resolution in mild COVID-19

Researchers from the US recently profiled the longitudinal immune response in mild COVID-19 patients starting with early time points of 1-15 days post-infection through convalescence to over 100 days after onset of symptoms.

1 Jun 2021

SARS-CoV-2 variants partially escape humoral immunity, but not T cells responses, study finds

Researchers at the Department of Viroscience, Erasmus MC, National Institute for Public Health and the Environment, Amsterdam UMC, and the Weill Medical College of Cornell University studied humoral and cellular immune responses to the wild type SARS-CoV-2, the B.1.1.7 variant (U.K. variant) and the B.1.351 variant (South African variant) in health care workers vaccinated with the BNT162b2 (Pfizer-BioNTech) mRNA vaccine.

31 May 2021

New drug effectively prevents severe COVID-19 in mice infected with SARS-CoV-2

The drug diABZI which activates the body's innate immune response -- was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2, according to scientists in the Perelman School of Medicine at the University of Pennsylvania

29 May 2021

Synbal and La Jolla Institute for Immunology collaborate to develop better COVID-19 models

The La Jolla Institute for Immunology (LJI) is partnering with Synbal, Inc., a preclinical biotechnology company based in San Diego, CA, to develop multi-gene, humanized mouse models for COVID-19 research. The research at LJI will be led by Professor Sujan Shresta, Ph.D., a member of the Institute's Center for Infectious Disease and Vaccine Research.

29 May 2021

Composition and function of gut microbiota are key in affecting immune responses to vaccinations

Varying immune response to vaccinations could be countered with microbiota-targeted interventions helping infants, older people and others to take full advantage of the benefits of effective vaccines, Australian and US experts say.

29 May 2021

“Good” bacteria demonstrate clinical potential for treating ulcerative colitis, Crohn's disease

A new study published in Nature Communications demonstrates that a consortium of bacteria designed to complement missing or underrepresented functions in the imbalanced microbiome of inflammatory bowel disease (IBD) patients, prevented and treated chronic immune-mediated colitis in humanized mouse models.

29 May 2021

Will emerging SARS-CoV-2 variants affect T cell immunity? A meta-analysis

New research by a team of scientists at The Hong Kong University of Science and Technology sheds light on the epitopic targets of SARS-CoV-2 by T cells in COVID-19 convalescents. The team’s findings suggest that the epitopes targeted by T cells during infection may not be affected by the emergence of SARS-CoV-2 variants.

28 May 2021

Researchers discover cross-reactive coronavirus antibody triggered during COVID-19 infection

Even before the COVID-19 pandemic, most people in the United States already had been sick with a coronavirus, albeit a far less dangerous one.

28 May 2021

Higher CD8 T cells may influence COVID-19 recovery in blood cancer patients

Antibodies aren't the only immune cells needed to fight off COVID-19 -; T cells are equally important and can step up to do the job when antibodies are depleted, suggests a new Penn Medicine study of blood cancer patients with COVID-19 published in Nature Medicine.

27 May 2021

Intensity and duration of SARS-CoV-2 immunity may depend on ABO blood group

A team of scientists from Canada and Spain recently evaluated the durability of antigen-specific immune responses in COVID-19 recovered individuals. They have also identified potential host factors associated with robust and long-lasting anti-SARS-CoV-2 immunity.

26 May 2021

Immunologists decode T cell responses that occur during COVID-19 infection

An international team of researchers from the Institute for Research in Biomedicine, affiliated to the Università della Svizzera italiana, has deciphered, at single cell resolution, the T cell responses occurring during COVID-19 infection.

26 May 2021

Human T cells can target more than 1,400 sites on SARS-CoV-2 virus

In a new paper, scientists from La Jolla Institute for Immunology (LJI) bring together research findings from COVID-19 researchers around the world.

25 May 2021

Study shows how neutralizing antibodies are produced after SARS-CoV-2 infection

A research group from Osaka University led by Professor Hisashi Arase and consisting of researchers from the Research Institute for Microbial Diseases, the Institute for Protein Research, the Immunology Frontier Research Center, the Center for Infectious Diseases, and the Graduate School of Medicine has discovered for the first time that both neutralizing antibodies that protect against infection as well as infection-enhancing antibodies that increase infectivity are produced after infection with SARS-CoV-2 by analyzing antibodies derived from COVID-19 patients.

25 May 2021

New collaborative effort to produce anti-HIV monoclonal antibodies

The Hotung Molecular Immunology group at St George's, University of London has partnered with Leaf Expression Systems, a contract development and manufacturing organization, specializing in plant-based expression and production of proteins, to explore the feasibility of producing anti-HIV monoclonal antibodies at large scale.

25 May 2021

Reduced levels of leptin are linked to poor vaccine responses in general population

Reduced levels of a metabolic hormone known as leptin is linked to poor vaccine antibody responses in the general population, a University of Queensland study has found.

24 May 2021

Mild cases of COVID-19 provide lasting antibody protection, shows study

Months after recovering from mild cases of COVID-19, people still have immune cells in their body pumping out antibodies against the virus that causes COVID-19, according to a study from researchers at Washington University School of Medicine in St. Louis. Such cells could persist for a lifetime, churning out antibodies all the while.

24 May 2021

Researchers investigate link between the liver’s immune system composition and NASH pathology

Our livers work hard to perform an entire range of activities: helping us digest food, maintaining body temperature and serving as an important checkpoint of the immune system for everything that we eat.

24 May 2021

Immunology News and Research

Latest Immunology News and Research

NCI grants more than $4.2 million to launch Cancer Epitope Database and Analysis Resource

Natural Killer cells acts as a potential target of immunotherapy, shows study

Depleting SIRPα-deficient in macrophages activate tumor antigen-specific cytotoxic T cells

Study offers longitudinal roadmap of immune activation and resolution in mild COVID-19

SARS-CoV-2 variants partially escape humoral immunity, but not T cells responses, study finds

New drug effectively prevents severe COVID-19 in mice infected with SARS-CoV-2

Synbal and La Jolla Institute for Immunology collaborate to develop better COVID-19 models

Composition and function of gut microbiota are key in affecting immune responses to vaccinations

“Good” bacteria demonstrate clinical potential for treating ulcerative colitis, Crohn's disease

Will emerging SARS-CoV-2 variants affect T cell immunity? A meta-analysis

Researchers discover cross-reactive coronavirus antibody triggered during COVID-19 infection

Higher CD8 T cells may influence COVID-19 recovery in blood cancer patients

Intensity and duration of SARS-CoV-2 immunity may depend on ABO blood group

Immunologists decode T cell responses that occur during COVID-19 infection

Human T cells can target more than 1,400 sites on SARS-CoV-2 virus

Study shows how neutralizing antibodies are produced after SARS-CoV-2 infection

New collaborative effort to produce anti-HIV monoclonal antibodies

Reduced levels of leptin are linked to poor vaccine responses in general population

Mild cases of COVID-19 provide lasting antibody protection, shows study

Researchers investigate link between the liver’s immune system composition and NASH pathology

A World First: sequencing polyclonal antibodies using only proteomics

The importance of social distancing for COVID-19 recovery in the US

Does the number of siblings you have affect your health?