Immunology

Immunology is the study of the body's immune system.

What is Immunology?

Immunology is the branch of biomedical science that deals with the response of an organism to antigenic challenge and its recognition of what is self and what is not. It deals with the defence mechanisms including all physical, chemical and biological properties of the organism that help it to combat its susceptibility to foreign organisms, material, etc.

The Different Types of Immunostaining

Cells of the Adaptive Immune System

Clinical Immunology

What does it mean to be Immunocompromised?

Classical Immunology

Improving Transplantation Outcomes in Positive Crossmatch Kidney Transplantation

Evolutionary Immunology

Mannan-binding Lectin Serine Protease (MASP) Family

The Immunological Functions of Red Blood Cells

What are the Types of Neuroinflammation?

B Cell Development

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Developmental Immunology

What are PARP inhibitors?

Cells of the Innate Immune System

What is Neuroimmunology?

Immunology: A Very British History

Latest Immunology News and Research

Insilico Medicine launches Pharma AI Spring Kickoff 2026 webinar

As the AI era becomes increasingly shaped by foundation models, the pharmaceutical industry is entering a new phase of opportunity for discovery, design, and decision-making driven by AI for science.

10 Apr 2026

Study identifies four radiomic profiles linked to sarcoidosis severity

Researchers have identified a new method for analyzing chest CT scans that may help physicians better understand the different forms of sarcoidosis, a complex inflammatory lung disease that affects more than 150,000 people in the United States.

9 Apr 2026

Study maps DNA methylation changes driving MDS stem cell dysfunction

Published on April 01, 2026, in Volume 2, article number 19 of the journal Immunity & Inflammation, a collaborative team led by Prof. Cao at the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, along with Dr. Liangding Hu at the Fifth Medical Center of Chinese PLA General Hospital, and Professors Qian Zhang and Yanmei Han at the National Key Laboratory of Immunity and Inflammation, Naval Medical University, has generated the first base-resolution DNA methylome of human MDS HSCs.

9 Apr 2026

AI-powered chemistry accelerates discovery of selective cancer inhibitors

Recently, the Insilico team's research entitled "An Internal Sulfur-Lone Pair Interaction Enabled the Discovery of Potential and Sub-Family Selective PKMYT1 Inhibitors" was invited for publication as a cover Feature in ChemMedChem.

9 Apr 2026

Insilico Medicine nominates AI-driven drug candidate for cancer, Cushing's syndrome and obesity

The NR3C1 (nuclear receptor subfamily 3 group C member 1) gene encodes the glucocorticoid receptor (GR), a nuclear receptor vital for maintaining physiological homeostasis, and inhibition of NR3C1 could increase the sensitivity of cancer cells to standard chemotherapy, particularly in ovarian cancer.

8 Apr 2026

High affinity for immune receptors predicts antibody drug associated anaphylaxis risk

Antibody therapeutics are laboratory-made proteins designed to work like the body's natural antibodies. They are widely used to treat diseases such as cancer by binding to specific targets, including cancer cells or inflammatory molecules.

8 Apr 2026

Novel screening method boosts early diagnosis of leprosy

A new blood test combined with a standardized questionnaire and artificial intelligence may transform the way leprosy is diagnosed in Brazil. Researchers at the University of São Paulo (USP) tested the new test in Brazil using blood samples collected during a COVID-19 population survey.

6 Apr 2026

Toxic RNA drives progressive heart damage in myotonic dystrophy

Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that leads to muscle weakness and wasting, but also affects the brain, the gastrointestinal tract and the heart.

3 Apr 2026

Organ-on-chip model advances study of sexually transmitted infections

Sexually transmitted infections (STIs) not only impact an individual's health but also result in multibillion-dollar economic losses worldwide.

3 Apr 2026

Deep UV microscopy enables label-free T cell characterization

A team of researchers at the Georgia Institute of Technology and Emory University has developed a deep-ultraviolet (UV) microscopy method that can rapidly assess T cell viability, activation state, and subtype-all without the need for fluorescent labels or cell destruction.

3 Apr 2026

Boosting mitochondrial function in dendritic cells can improve cancer immunotherapy

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring their energy production can improve immunotherapy. Dendritic cells activate the cytotoxic immune cells that destroy cancer.

2 Apr 2026

Regulatory T cells may influence inflammation and behavior in autism

Two new studies from the UC Davis MIND Institute examined regulatory T cells (Tregs) and their potential role in neuroinflammation and behavioral changes associated with autism.

2 Apr 2026

New dual drugs eliminate tumors when combined with immunotherapy

Researchers at Johns Hopkins University and the University of Maryland School of Pharmacy have developed a set of novel, first-in-class drugs that inhibit hypoxia-inducible factors 1 and 2, a pair of transcription factors considered to be "master regulators" of cancer progression.

2 Apr 2026

International researchers set new standards for studying tumor microbiota

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.

2 Apr 2026

Lipid nanoparticles help CAR T cells melt pancreatic cancer barriers

Often diagnosed when surgery is no longer an option, pancreatic cancer is one of the most difficult cancers to treat and has one of the lowest rates of survival among major malignancies.

31 Mar 2026

Gut-derived metabolites regulate immune cells in complex ways

Published on March 23, 2026, in Volume 2, article number 18 of the journal Immunity & Inflammation, the review begins by systematically outlining the sources and synthetic pathways of immune-relevant microbial metabolites, including bile acids, short-chain fatty acids, amino acid derivatives, vitamins, trimethylamine/trimethylamine N-oxide, and odd-chain fatty acids.

31 Mar 2026

Gut immune responses found to trigger brain inflammation in MS

Multiple sclerosis (MS) is a debilitating neurological disorder caused by malfunctioning immune responses that target the brain and spinal cord of the central nervous system (CNS).

27 Mar 2026

Drugs targeting TIE2 protein could help prevent formation of cerebral cavernous malformations

Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a cell surface receptor protein called TIE2 as the missing link between two key signaling pathways that drive the growth of blood vessel abnormalities known as cerebral cavernous malformations (CCMs).

27 Mar 2026

Study reveals genetic evolution of major malaria vector species in South America

Anopheles darlingi mosquitoes-a major vector of malaria in South America-are evolving in response to insecticides, which may make them harder to kill and malaria more difficult to control, according to a new study led by Harvard T.H. Chan School of Public Health.

27 Mar 2026