Immunology News and Research

Latest Immunology News and Research

Mount Sinai-led research uncovers mechanisms behind Crohn's disease inflammation

A research team led by Mount Sinai has uncovered mechanisms of abnormal immune cell function that may lead to Crohn's disease, according to findings published in Science Immunology on March 21.

22 Mar 2025

Targeting brain’s waste removal system may help combat cognitive decline

As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease, among others.

21 Mar 2025

Drug-resistant bacteria evolve to weaponize an antimicrobial genetic tool

A drug-resistant type of bacteria that has adapted to health care settings evolved in the past several years to weaponize an antimicrobial genetic tool, eliminating its cousins and replacing them as the dominate strain.

21 Mar 2025

High-fat diet impairs neutrophil function in obesity

A new study in The Journal of Immunology reveals how a high-fat diet may impair the immune system's ability to respond to infection by impacting the function of neutrophils, one of the first immune cells to respond to bacteria or viruses.

20 Mar 2025

Targeted inhibition of a 'signal jammer' protein may improve tumor response to immunotherapy

Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, a new study demonstrates how some cancer cells use the protein voltage-dependent anion channel 2 (VDAC2) like a signal jammer to prevent the body's anticancer systems from communicating with the immune system.

19 Mar 2025

Study reveals how B cells safeguard high-affinity antibodies

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies.

19 Mar 2025

Research findings solve the paradox of how the immune system balances speed and precision

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted to keep different pathogens in check.

19 Mar 2025

Testing a novel approach to restore normal heart function in Myotonic Dystrophy Type 1

Myotonic Dystrophy Type 1 (DM1) is the most common adult-onset form of muscular dystrophy and a condition that severely affects multiple organs including skeletal muscle, heart, brain and the gastrointestinal tract.

18 Mar 2025

Coalition of experts reaffirms vaccines as essential for public health

In response to growing concerns over vaccine misinformation, declining public trust in science, and recent outbreaks of preventable diseases, a coalition of 34 scientific and medical organizations, led by the American Association of Immunologists (AAI) and the American College of Physicians (ACP), has issued a unified statement emphasizing the critical role of vaccinations in public health.

18 Mar 2025

Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder

A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and inflammation in the central nervous system in individuals with Down syndrome Regression Disorder (DSRD).

14 Mar 2025

Mitochondria may hold key to reducing inflammaging in aging cells

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

14 Mar 2025

Semi-synthetic bile acid could be a promising therapeutic option for TH17-mediated intestinal diseases

A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation.

14 Mar 2025

NIH researchers define topical steroid withdrawal diagnostic criteria

Researchers at the National Institutes of Health (NIH) have determined that dermatitis resulting from topical steroid withdrawal (TSW) is distinct from eczema and is caused by an excess of an essential chemical compound in the body.

14 Mar 2025

COVID-19 discovery could open the door to new treatments for chronic lung diseases

University of Virginia School of Medicine scientists have discovered how severe COVID-19 can destroy immune cells' ability to repair the lungs, helping explain the lingering effects of long COVID.

13 Mar 2025

IgE antibodies show promise in targeting HER2 cancers resistant to other therapies

Antibody treatment which activates the patient's own immune system against cancer, known as immunotherapy, is increasingly being investigated as an alternative for chemotherapy and radiotherapy.

12 Mar 2025

Nanogels can improve antibiotic delivery for urinary tract infections

Researchers from the University of Colorado Anschutz Medical Campus studied a new method to deliver antibiotics, specifically gentamicin, directly into the bladder tissue to better treat UTIs.

12 Mar 2025

Researchers identify cause of post-COVID inflammatory shock in children

MIS-C is a serious inflammatory shock that affects children. It can occur several weeks after a COVID infection and can be life-threatening.

12 Mar 2025

Updates on influenza vaccine strain recommended by WHO (2025-2026 northern hemisphere)

To maintain vaccine efficacy, WHO regularly updates influenza vaccine strains based on global epidemiological, virological, and serological analyses.

From Sino Biological Inc. 12 Mar 2025

New malaria control strategy targets protein system in mosquitoes

A molecular quality-control system in Anopheles mosquitoes-the species responsible for most of the world's malaria cases-is a promising target for future malaria-control strategies, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

11 Mar 2025

Combination of Epstein-Barr virus antibodies and genes linked to increased risk of MS

In multiple sclerosis (MS), antibodies to the common Epstein-Barr virus can accidentally attack a protein in the brain and spinal cord. New research shows that the combination of certain viral antibodies and genetic risk factors can be linked to a greatly increased risk of MS.

10 Mar 2025

Immunology News and Research

Latest Immunology News and Research

Mount Sinai-led research uncovers mechanisms behind Crohn's disease inflammation

Targeting brain’s waste removal system may help combat cognitive decline

Drug-resistant bacteria evolve to weaponize an antimicrobial genetic tool

High-fat diet impairs neutrophil function in obesity

Targeted inhibition of a 'signal jammer' protein may improve tumor response to immunotherapy

Study reveals how B cells safeguard high-affinity antibodies

Research findings solve the paradox of how the immune system balances speed and precision

Testing a novel approach to restore normal heart function in Myotonic Dystrophy Type 1

Coalition of experts reaffirms vaccines as essential for public health

Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder

Mitochondria may hold key to reducing inflammaging in aging cells

Semi-synthetic bile acid could be a promising therapeutic option for TH17-mediated intestinal diseases

NIH researchers define topical steroid withdrawal diagnostic criteria

COVID-19 discovery could open the door to new treatments for chronic lung diseases

IgE antibodies show promise in targeting HER2 cancers resistant to other therapies

Nanogels can improve antibiotic delivery for urinary tract infections

Researchers identify cause of post-COVID inflammatory shock in children

Updates on influenza vaccine strain recommended by WHO (2025-2026 northern hemisphere)

New malaria control strategy targets protein system in mosquitoes

Combination of Epstein-Barr virus antibodies and genes linked to increased risk of MS

eBook: Cell-based technologies in drug discovery and Immunotherapy eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?