Immunotherapy News and Research

Latest Immunotherapy News and Research

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

16 Mar 2023

Study focuses on new approach that delivers a "one-two punch" to help T cells attack solid tumors

A new approach that delivers a "one-two punch" to help T cells attack solid tumors is the focus of a preclinical study by researchers from the Perelman School of Medicine at the University of Pennsylvania.

15 Mar 2023

Research uncovers a possible explanation for sex differences in pancreatic cancer

Immunotherapy is an effective form of therapy for different types of cancer. However, for pancreatic cancer, its effect is limited and differs between men and women.

15 Mar 2023

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

A new study published in Science Immunology points to a promising therapeutic approach for future cancer treatments based on natural killer cells (NK), which are immune cells that bind to tumor cells and destroy them.

14 Mar 2023

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

A type of immune therapy called chimeric antigen receptor (CAR)-T cell therapy has revolutionized the treatment of multiple types of blood cancers but has shown limited efficacy against glioblastoma - the deadliest type of primary brain cancer - and other solid tumors.

14 Mar 2023

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy.

13 Mar 2023

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including the most common type of head and neck cancer, and elevated levels of white blood cells that produce antibodies within tumors.

13 Mar 2023

Components of the gut microbiome could be used to better predict efficacy of CAR-T cell therapy

Even though, according to recent preliminary studies, the risk of dying from cancer has declined within the European Union in recent years, cancers remain among the leading causes of death.

13 Mar 2023

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs.

9 Mar 2023

Study suggests a new approach for treating metastatic breast cancers

Metastatic breast cancer has no cure and has proven stubbornly resistant to one of the most innovative and promising new cancer treatments: immunotherapy.

8 Mar 2023

Yale scientists seek to identify optimal sequential treatments for advanced cancer

A team of Yale scientists seeks to determine which treatment sequences produce the best results for people with advanced cancer while examining the cost of these treatments.

6 Mar 2023

Discovery about cell membrane 'blebs' could lead to new ways to fight melanoma

Cell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern study suggests.

3 Mar 2023

Quiescent ovarian cancer cells secrete a protein to induce chemotherapy resistance in neighboring cells

Certain chemotherapy-resistant ovarian cancer cells protect neighboring cancer cells by sending signals that induce resistance, according to a new study from University of Pittsburgh and UPMC researchers that may help explain why ovarian cancer patients respond poorly to chemotherapy or relapse after treatment.

3 Mar 2023

AI diagnostic tool can predict the risk of flare-ups for ulcerative colitis

Ulcerative colitis assessment could be improved after new research shows that an artificial intelligence model could predict flare-ups and complications after reading biopsies.

3 Mar 2023

Starting immunotherapy before surgery improves the outlook for patients with stage III-IV melanoma

Patients with high-risk melanoma who received the immunotherapy drug pembrolizumab both before and after surgery to remove cancerous tissue had a significantly lower risk of their cancer recurring than similar patients who received the drug only after surgery.

1 Mar 2023

Clinical study reveals new use for high blood pressure drug in pediatric patients

A clinical study conducted by Indiana University School of Medicine researchers revealed that oral verapamil, a readily available and commonly used drug to treat high blood pressure and heart conditions, can also improve the pancreas' insulin secretion in children with newly-diagnosed type 1 diabetes (T1D).

1 Mar 2023

Immunotherapy News and Research

Latest Immunotherapy News and Research

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

Study focuses on new approach that delivers a "one-two punch" to help T cells attack solid tumors

Research uncovers a possible explanation for sex differences in pancreatic cancer

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Components of the gut microbiome could be used to better predict efficacy of CAR-T cell therapy

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

Study suggests a new approach for treating metastatic breast cancers

Yale scientists seek to identify optimal sequential treatments for advanced cancer

Discovery about cell membrane 'blebs' could lead to new ways to fight melanoma

Quiescent ovarian cancer cells secrete a protein to induce chemotherapy resistance in neighboring cells

AI diagnostic tool can predict the risk of flare-ups for ulcerative colitis

Starting immunotherapy before surgery improves the outlook for patients with stage III-IV melanoma

Clinical study reveals new use for high blood pressure drug in pediatric patients

New imaging method could help make better decisions on personalized cancer treatment

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Largest genomic study focuses on the prognosis of metastatic pheochromocytomas

First small molecules designed to stimulate immune cells against neuroblastoma

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

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