Immunotherapy

Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

What is Immunotherapy?

Immunotherapy is a treatment that is designed to harness the ability of the body’s immune system to combat infection or disease.

Adoptive T Cell Therapy Methodology

Adoptive T Cell Therapy Applications

Activation Immunotherapies

Suppression Immunotherapies

Immunotherapy and Helminthic Therapy

Immunotherapy: The Future of Lung Cancer Treatment?

Immunotherapy: Past, Present and Future

Neoantigens' Role in Immunotherapy

Latest Immunotherapy News and Research

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression.

31 Oct 2025

Study reveals how melanoma evolves to resist immunotherapy

A study led by UCLA Health Jonsson Comprehensive Cancer Center investigators reveals how melanoma, the deadliest form of skin cancer, evolves to resist immunotherapy and identifies a potential strategy to prevent or reverse that resistance.

31 Oct 2025

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Cancer immunotherapy, which uses drugs that stimulate the body's immune cells to attack tumors, is a promising approach to treating many types of cancer. However, it doesn't work well for some tumors, including ovarian cancer.

31 Oct 2025

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

For more than a year, Diane Hunter, now 72, had been experiencing vague symptoms — pain in her spine and hips, nausea, exhaustion, thirst, and frequent urination.

31 Oct 2025

Advances in diagnosis and management of systemic light chain amyloidosis

Systemic light chain (AL) amyloidosis is a rare and life-threatening disorder characterized by the deposition of misfolded immunoglobulin light chains as insoluble amyloid fibrils in various tissues and organs, leading to progressive structural and functional impairment.

30 Oct 2025

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment

Gastric cancer remains a major global health challenge, characterized by high mortality and limited therapeutic efficacy, especially in advanced stages.

30 Oct 2025

Pharmacists can help control blood sugar in cancer patients with diabetes

People with cancer who received diabetes care from clinical pharmacists achieved significantly better blood sugar control, according to new research from the University of California San Diego.

30 Oct 2025

Targeting myeloid cells to enhance cancer immunotherapy

Mayo Clinic researchers have identified a specific immune cell that can be targeted to give a boost to standard immunotherapies for cancer.

29 Oct 2025

Harnessing extracellular vesicles for targeted lung cancer treatment

In the quest for more targeted lung cancer treatments, a researcher at the University of Missouri thinks the solution may lie in tiny bubble-shaped packages that cells use to talk to each other.

29 Oct 2025

AI indelibly transforms solid tumor drug development

Artificial intelligence (AI) is fundamentally reshaping the landscape of solid tumor (ST) drug development.

29 Oct 2025

Novel computational platform can design synthetic protein receptors from scratch

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), have revolutionized cancer treatment.

28 Oct 2025

Study finds up to 5% of Americans carry genetic mutations linked to increased cancer susceptibility

New Cleveland Clinic research reveals that up to 5% of Americans – approximately 17 million people – carry genetic mutations or "variants" linked to increased cancer susceptibility, regardless of risk factors like personal or family cancer history.

27 Oct 2025

Mitochondria and lysosomes work together to control regulatory T cell activation

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system.

24 Oct 2025

Leveraging the power of T cells for more effective and durable cancer immunotherapies

T cells play central roles in the adaptive immune response against cancer. Their functional inactivation is a primary driver of tumor progression, making the reactivation of T cell function a main goal in immunotherapy.

24 Oct 2025

How COVID mRNA vaccines may make cancer treatments more effective

Researchers found that COVID-19 mRNA vaccines, when given within 100 days of starting immune checkpoint inhibitors, were linked to significantly longer survival in lung and melanoma cancer patients. The vaccines trigger a powerful type-I interferon response that primes tumors to become more responsive to immunotherapy.

23 Oct 2025

Antibody discovery could provide new treatment options for aggressive breast cancers

A new potential antibody therapy strategy which restricts the growth of treatment-resistant breast cancers has been developed by scientists.

23 Oct 2025

New type of immunotherapy could change the treatment plan for triple-negative breast cancer

Triple-negative breast cancer is one of the most aggressive cancers. The name tells the story: It lacks the three main targets that make other types of breast cancers more treatable with powerful therapies.

22 Oct 2025

New technology can track beneficial bacteria after fecal microbiota transplants

Researchers at the Icahn School of Medicine at Mount Sinai and their collaborators have developed a new technology to track beneficial bacteria after fecal microbiota transplants (FMT).

22 Oct 2025

$VT3989 shows promising antitumor activity in refractory mesothelioma patients$

VT3989 shows promising antitumor activity in refractory mesothelioma patients

The first-in-class YAP-TEAD inhibitor VT3989 continued to be well tolerated and demonstrated notable initial antitumor activity, particularly in patients with refractory mesothelioma, according to results from a trial led by researchers from The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Oral targeted therapy shrinks tumors in over 70% of patients with HER2-mutant NSCLC

The oral targeted therapy sevabertinib led to tumor reduction and manageable side effects in patients with HER2-mutant non-small cell lung cancer (NSCLC), according to data from a trial led by researchers at The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Immunotherapy

Overview

Adoptive T Cell Therapy Methodology

Adoptive T Cell Therapy Applications

Activation Immunotherapies

Feature Articles

Suppression Immunotherapies

Immunotherapy and Helminthic Therapy

Immunotherapy: The Future of Lung Cancer Treatment?

Immunotherapy: Past, Present and Future

Neoantigens' Role in Immunotherapy

Latest Immunotherapy News and Research

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Study reveals how melanoma evolves to resist immunotherapy

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

Advances in diagnosis and management of systemic light chain amyloidosis

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment

Pharmacists can help control blood sugar in cancer patients with diabetes

Targeting myeloid cells to enhance cancer immunotherapy

Harnessing extracellular vesicles for targeted lung cancer treatment

AI indelibly transforms solid tumor drug development

Novel computational platform can design synthetic protein receptors from scratch

Study finds up to 5% of Americans carry genetic mutations linked to increased cancer susceptibility

Mitochondria and lysosomes work together to control regulatory T cell activation

Leveraging the power of T cells for more effective and durable cancer immunotherapies

How COVID mRNA vaccines may make cancer treatments more effective

Antibody discovery could provide new treatment options for aggressive breast cancers

New type of immunotherapy could change the treatment plan for triple-negative breast cancer

New technology can track beneficial bacteria after fecal microbiota transplants

VT3989 shows promising antitumor activity in refractory mesothelioma patients

Oral targeted therapy shrinks tumors in over 70% of patients with HER2-mutant NSCLC

eBook: Cell-based technologies in drug discovery and Immunotherapy eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Immunotherapy

Overview

Feature Articles

Suppression Immunotherapies

Immunotherapy and Helminthic Therapy

Immunotherapy: The Future of Lung Cancer Treatment?

Immunotherapy: Past, Present and Future

Neoantigens' Role in Immunotherapy

Latest Immunotherapy News and Research

eBook: Cell-based technologies in drug discovery and Immunotherapy eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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