Immunotherapy

Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

What is Immunotherapy?

Immunotherapy is a treatment that is designed to harness the ability of the body’s immune system to combat infection or disease.

Adoptive T Cell Therapy Applications

Immunotherapy and Helminthic Therapy

Immunotherapy: The Future of Lung Cancer Treatment?

Neoantigens' Role in Immunotherapy

Immunotherapy: Past, Present and Future

Activation Immunotherapies

Adoptive T Cell Therapy Methodology

Suppression Immunotherapies

Latest Immunotherapy News and Research

Dietary restriction boosts antitumour immunity by rewiring T cell metabolism

Dietary restriction reshapes CD8+ T cell metabolism by increasing ketone body–driven acetyl-CoA production, preventing terminal exhaustion and enhancing tumour control in mice. This metabolic reprogramming also boosts responsiveness to PD-1 blockade, suggesting a potential strategy to improve cancer immunotherapy.

10 Dec 2025

Anxiety and insomnia linked to reduced natural killer cell levels in young women

Natural killer (NK) cells are the bodyguards of our immune system. As a first line of defense, they destroy invading pathogens, foreign bodies, and infected cells in early stages, thereby preventing them from spreading.

10 Dec 2025

Triaptosis could be a promising strategy in the fight against cancer

Cancer remains one of the most critical global public health challenges, exerting profound social, economic, and clinical burdens while limiting gains in human life expectancy.

10 Dec 2025

Dietary restriction reprograms cancer-fighting immune cells to enhance anti-tumour immunity

Reducing calorie intake helps cancer-fighting immune cells do their jobs more effectively, reports a study by Van Andel Institute scientists and collaborators.

9 Dec 2025

New antibody shows ability to overcome treatment resistance in blood cancers and solid tumors

In a new preclinical study, researchers from The University of Texas MD Anderson Cancer Center developed an antibody therapy called 77A that showed an ability to overcome treatment resistance in blood cancers, such as myeloma and lymphoma, as well as solid tumors.

9 Dec 2025

Patients receiving T-cell redirecting therapies can safely be monitored at home

Patients who receive T-cell redirecting therapies are typically hospitalized for several days after treatment to watch for side effects.

9 Dec 2025

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in helping children and adults fight a rare and aggressive form of blood cancer called T-cell acute lymphoblastic leukemia (T-ALL).

8 Dec 2025

Targeted approach of immunotherapy improves sepsis outcomes

Immunotherapy for sepsis is effective when doctors tailor the treatment precisely to the patient's immune system condition.

8 Dec 2025

Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause

Serious side effects, including neurotoxicity and intestinal inflammation, that appear weeks or months after patients receive CAR T cell therapy for multiple myeloma share a common immune root cause, are associated with high rates of death unrelated to cancer relapse-primarily infection-and may be avoidable.

8 Dec 2025

Receiving immunotherapy earlier in the day may improve survival in cancer patients

Receiving anticancer immunotherapy earlier in the day may help individuals with cancer live longer. That's according to a study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

8 Dec 2025

Lower dose of immunotherapy for malignant melanoma improves results

According to a new study, lower doses of approved immunotherapy for malignant melanoma can give better results against tumors, while reducing side effects.

8 Dec 2025

Chemotherapy-free combination treatment outperforms traditional regimens in patients with Ph+ ALL

A chemotherapy-free combination treatment outperformed a combination of targeted therapy and chemotherapy among patients with Ph+ acute lymphoblastic leukemia (ALL) in a new study.

7 Dec 2025

New trial shows major survival gains with epcoritamab added to standard R2 therapy

In a new trial, patients with follicular lymphoma had a significantly higher response to treatment and a nearly 80% reduction in the risk of death or disease progression if they received epcoritamab in addition to the standard second-line regimen versus the standard regimen alone.

7 Dec 2025

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with targeted therapies.

5 Dec 2025

Engineered herpes virus activates potent immune responses against glioblastoma

Researchers at Mass General Brigham have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells.

4 Dec 2025

Study uncovers strategy to sensitize estrogen receptor–positive breast tumors to immunotherapy

A study led by researchers at the Hospital del Mar Research Institute advances one of the most significant milestones in breast cancer treatment, making immunotherapy effective against the most common tumor type, estrogen receptor-positive or luminal breast cancer.

4 Dec 2025

Generative AI aids discovery of ISM3830's novel scaffold

Casitas B-lineage lymphoma-b (CBLB) is an E3 ubiquitin–protein ligase that functions as an intracellular checkpoint and master negative regulator of T‑cell and natural killer (NK) cell activation, playing a central role in modulating T-cell activation and immune tolerance, and its inhibition enhances T cells and NK cells function, also provides a strategy for the function restoration of exhausted T cells.

1 Dec 2025

Triaptosis-based therapeutic innovations could offer renewed hope for cancer patients

Cancer remains one of the most critical global public health challenges, exerting profound social, economic, and clinical burdens while limiting gains in human life expectancy.

1 Dec 2025

Combination immunotherapy may be the key to control HIV without long-term antiviral treatment

A new study from UC San Francisco shows it may be possible to control HIV without long-term antiviral treatment - an advance that points the way toward a possible cure for a disease that affects 40 million people around the world.

1 Dec 2025

Study demonstrates a safer strategy for allogeneic stem cell transplants

In preclinical studies, researchers found that priming the immune system with a Treg-expanding therapy before stem cell transplant boosted survival, protected vital organs, and promoted a balanced gut microbiome-offering hope for safer, more effective treatment of blood cancers.

27 Nov 2025

Immunotherapy

Overview

Adoptive T Cell Therapy Applications

Immunotherapy and Helminthic Therapy

Immunotherapy: The Future of Lung Cancer Treatment?

Feature Articles

Neoantigens' Role in Immunotherapy

Immunotherapy: Past, Present and Future

Activation Immunotherapies

Adoptive T Cell Therapy Methodology

Suppression Immunotherapies

Latest Immunotherapy News and Research

Dietary restriction boosts antitumour immunity by rewiring T cell metabolism

Anxiety and insomnia linked to reduced natural killer cell levels in young women

Triaptosis could be a promising strategy in the fight against cancer

Dietary restriction reprograms cancer-fighting immune cells to enhance anti-tumour immunity

New antibody shows ability to overcome treatment resistance in blood cancers and solid tumors

Patients receiving T-cell redirecting therapies can safely be monitored at home

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

Targeted approach of immunotherapy improves sepsis outcomes

Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause

Receiving immunotherapy earlier in the day may improve survival in cancer patients

Lower dose of immunotherapy for malignant melanoma improves results

Chemotherapy-free combination treatment outperforms traditional regimens in patients with Ph+ ALL

New trial shows major survival gains with epcoritamab added to standard R2 therapy

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Engineered herpes virus activates potent immune responses against glioblastoma

Study uncovers strategy to sensitize estrogen receptor–positive breast tumors to immunotherapy

Generative AI aids discovery of ISM3830's novel scaffold

Triaptosis-based therapeutic innovations could offer renewed hope for cancer patients

Combination immunotherapy may be the key to control HIV without long-term antiviral treatment

Study demonstrates a safer strategy for allogeneic stem cell transplants

Event guide: 7th Allogeneic Cell Therapies Summit eBook

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Extending the reach of Amperia™

Immunotherapy

Overview

Feature Articles

Neoantigens' Role in Immunotherapy

Immunotherapy: Past, Present and Future

Activation Immunotherapies

Adoptive T Cell Therapy Methodology

Suppression Immunotherapies

Latest Immunotherapy News and Research

Event guide: 7th Allogeneic Cell Therapies Summit eBook

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Extending the reach of Amperia™

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