Immunotherapy

What is Immunotherapy?

Immunotherapy is treatment that is designed to harness the ability of the body’s immune system to combat infection or disease. Immunotherapy might produce an immune response to disease or enhance the immune system’s resistance to active diseases such as cancer.

Activation Immunotherapies

Immunotherapy and Helminthic Therapy

Suppression Immunotherapies

Immunotherapy: past, present and future

Adoptive T Cell Therapy Methodology

Adoptive T Cell Therapy Applications

Immunotherapy: The Future of Lung Cancer Treatment?

Latest Immunotherapy News and Research

Combination of radiation and immunotherapy shows promise for advanced head and neck cancers

A new phase II trial finds that a combination of radiation therapy and immunotherapy led to encouraging survival outcomes and acceptable toxicity for patients with locally advanced head and neck squamous cell carcinoma

27 Feb 2020

Pre-operative immunotherapy can elicit an immune response that shrinks oral cancers

A new clinical trial suggests that immunotherapy given before other treatments for oral cavity cancers can elicit an immune response that shrinks tumors, which could provide long-term benefit for patients.

27 Feb 2020

Drug used for breast, renal cancers may provide survival benefit for patients with head and neck cancers

A targeted therapy drug used for breast and kidney cancers may also extend progression-free survival for patients with advanced head and neck cancer who are at high risk for recurrence after standard treatment.

27 Feb 2020

NTHU research team develops new treatment for cancer

A research team led by Dr. Yunching Chen and Tsai-Te Lu of National Tsing Hua University have recently developed a new treatment for cancer, in which blood vessels within malignant tumors are normalized by injecting a specially developed nanodelivery system for nitric oxide (NanoNO), which also facilitates the delivery of cancer drugs and immunocytes into the tumor.

27 Feb 2020

Brain imaging may help predict when liquid biopsy will benefit individual glioblastoma patients

Tracking brain cancer with a blood test instead of a surgical biopsy may greatly improve quality of life for glioblastoma (GBM) patients and provide critical information for their care, but it is not feasible in all cases.

27 Feb 2020

UC researchers uncover potential new treatment for patients with metastatic melanoma

Researchers at the University of Cincinnati have uncovered a potentially more beneficial treatment regimen for patients with metastatic melanoma.

26 Feb 2020

New method to deliver an immune system 'uncloaking' device directly to cancer cells

Scientists at Johns Hopkins report they have designed and successfully tested an experimental, super small package able to deliver molecular signals that tag implanted human cancer cells in mice and make them visible for destruction by the animals' immune systems.

26 Feb 2020

Biomarkers in blood samples can predict clinical response to immunotherapy in metastatic NSCLC

Non-small cell lung cancer patients with higher measures of tumor mutations that show up in a blood test generally have a better clinical response to PD-1-based immunotherapy treatments than patients with a lower measure of mutations.

26 Feb 2020

Aggressive cancers set up a structural framework to keep the immune system at bay

Aggressive colorectal cancers set up an interactive network of checkpoints to keep the immune system at bay, scientists report.

26 Feb 2020

Scientists developing a combined vaccine to fight most malignant brain tumor

Scientists are developing a combined vaccine to fight the most deadly form of brain cancer.

25 Feb 2020

Transferring knowledge, not anxiety, can help food-allergic children cope with their fears

A new article in Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology discusses the difficulties faced by parents of children with food allergies in not transferring their own anxieties to their children.

25 Feb 2020

Researchers identify mechanisms underlying immunotherapy-associated tuberculosis

Researchers at the University of Southampton have identified how new checkpoint inhibitor treatments for cancer can activate tuberculosis in some patients.

24 Feb 2020

Immunotherapy drug combination effective for patients with fast-growing neuroendocrine tumors

Many patients with rare, fast-growing neuroendocrine tumors respond well to a common immunotherapy drug combination, according to the first peer-reviewed publication out of DART, short for Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors, a unique rare cancer clinical trial.

24 Feb 2020

Discovery may open up new avenues into improving cancer immunotherapy

New cancer immunotherapy approaches are revolutionizing treatment options for breast cancer patients. However, many lead to insufficient immune responses rendering the therapies incapable of completely eradicating tumors.

23 Feb 2020

UT Dallas scientists awarded CPRIT grants for lung, kidney cancer research

The Cancer Prevention and Research Institute of Texas has awarded new grants totaling $1.8 million to two University of Texas at Dallas scientists for their research related to lung and kidney cancers.

23 Feb 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

Using newly discovered immune cell type to fight pancreatic cancer

Immunotherapy is showing great promise for treating cancer. But so far, this approach has been effective in only about 20% of all cancers. To advance those results, researchers are looking for new ways to mobilize the immune system to destroy tumors.

23 Feb 2020

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.

22 Feb 2020

Administering immunotherapy alongside chemoradiation for advanced NSCLC appears to be safe and tolerable

Research from Rutgers Cancer Institute of New Jersey shows administering the immunotherapy drug pembrolizumab together with chemotherapy given at the same time as radiation treatment (chemoradiation) is safe and tolerable as a first-line therapy for patients with stage 3 non-small cell lung cancer.

21 Feb 2020

UAH research could have broad implications for immunotherapy and cancer treatment

Research into engineering artificial organs that mimic the functions of human lymph nodes at The University of Alabama in Huntsville has garnered one of its professors a $507,777 National Science Foundation Faculty Early Career Development Program Award.

21 Feb 2020

Immunotherapy

Overview

Activation Immunotherapies

Immunotherapy and Helminthic Therapy

Suppression Immunotherapies

Feature Articles

Immunotherapy: past, present and future

Adoptive T Cell Therapy Methodology

Adoptive T Cell Therapy Applications

Immunotherapy: The Future of Lung Cancer Treatment?

Latest Immunotherapy News and Research

Combination of radiation and immunotherapy shows promise for advanced head and neck cancers

Pre-operative immunotherapy can elicit an immune response that shrinks oral cancers

Drug used for breast, renal cancers may provide survival benefit for patients with head and neck cancers

NTHU research team develops new treatment for cancer

Brain imaging may help predict when liquid biopsy will benefit individual glioblastoma patients

UC researchers uncover potential new treatment for patients with metastatic melanoma

New method to deliver an immune system 'uncloaking' device directly to cancer cells

Biomarkers in blood samples can predict clinical response to immunotherapy in metastatic NSCLC

Aggressive cancers set up a structural framework to keep the immune system at bay

Scientists developing a combined vaccine to fight most malignant brain tumor

Transferring knowledge, not anxiety, can help food-allergic children cope with their fears

Researchers identify mechanisms underlying immunotherapy-associated tuberculosis

Immunotherapy drug combination effective for patients with fast-growing neuroendocrine tumors

Discovery may open up new avenues into improving cancer immunotherapy

UT Dallas scientists awarded CPRIT grants for lung, kidney cancer research

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Using newly discovered immune cell type to fight pancreatic cancer

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Administering immunotherapy alongside chemoradiation for advanced NSCLC appears to be safe and tolerable

UAH research could have broad implications for immunotherapy and cancer treatment

Isolating Single T-cells of Interest using an Optofluidic Platform

Microscopy in Neuroscience Research

Universal 'One-Size-Fits-All' Cancer Treatment