Immunotherapy

Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

What is Immunotherapy?

Immunotherapy is a treatment that is designed to harness the ability of the body’s immune system to combat infection or disease.

Activation Immunotherapies

Immunotherapy and Helminthic Therapy

Suppression Immunotherapies

Immunotherapy: Past, Present and Future

Adoptive T Cell Therapy Methodology

Adoptive T Cell Therapy Applications

Immunotherapy: The Future of Lung Cancer Treatment?

Latest Immunotherapy News and Research

Study shows how melanoma cells evade detection and destruction by immune cells

A dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, including melanoma.

9 Apr 2021

Increased incidence of melanoma in Utah points to overdiagnosis

A letter published today by Huntsman Cancer Institute (HCI) at the University of Utah (U of U) in the New England Journal of Medicine reports that melanoma mortality among Utahns outpaced that of the rest of the United States during the period from 1975 to 2013.

9 Apr 2021

A collaborative effort to evaluate treatment of liver and pancreatic tumors

The University of Texas MD Anderson Cancer Center and TriSalus Life Sciences today announced a strategic research collaboration to evaluate the treatment of tumors of the pancreas and liver by integrating interventional delivery of SD-101.

8 Apr 2021

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

A clinical trial is underway to determine whether people who are highly allergic or have a mast cell disorder are at increased risk for an immediate, systemic allergic reaction to the Moderna or Pfizer-BioNTech COVID-19 vaccines.

7 Apr 2021

New research could rescue failed immunotherapies for treating solid tumors

New research from the UVA Cancer Center could rescue once-promising immunotherapies for treating solid cancer tumors, such as ovarian, colon and triple-negative breast cancer, that ultimately failed in human clinical trials.

7 Apr 2021

Phase 1 clinical trial to test a new, potential method against cancer

A potential new weapon against cancer is entering the first phase of clinical trials thanks to a collaboration between Spectrum Health, the Lansing-based company Niowave and Michigan State University.

7 Apr 2021

High expression of cell death genes may increase risk of early death from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

5 Apr 2021

New software package employs deep-learning algorithms to analyze T-cell receptor sequencing data

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center have developed DeepTCR, a software package that employs deep-learning algorithms to analyze T-cell receptor (TCR) sequencing data. T-cell receptors are found on the surface of immune T cells.

5 Apr 2021

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule.

3 Apr 2021

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study for neuroblastoma and melanoma.

3 Apr 2021

Stem cell transplants offer long-term benefits for pediatric cancer patients receiving immunotherapy

Children and young adults who receive CAR T-cell therapy for the most common childhood cancer - acute lymphoblastic leukemia - suffer remarkably fewer relapses and are far more likely to survive when the treatment is paired with a subsequent stem cell transplant, a new study finds.

1 Apr 2021

Modest dietary changes and exercise can improve survival outcomes for young people with leukemia

In some cancers, including leukemia in children and adolescents, obesity can negatively affect survival outcomes. Obese young people with leukemia are 50% more likely to relapse after treatment than their lean counterparts.

1 Apr 2021

Evidence-based clinical practice guideline aims to optimize PD-L1 lung tumor testing

The College of American Pathologists (CAP), in collaboration with five other societies, developed a draft evidence-based clinical practice guideline that aims to optimize PD-L1 testing for patients with non-small cell lung cancer (NSCLC) who are being considered for immunooncology therapy.

1 Apr 2021

Study confirms the predictive value of molecular classification of hormone-sensitive breast cancer

Barcelona researchers at the Hospital Clínic-IDIBAPS Research Institute, the University of Barcelona and the SOLTI academic cancer research group have shown that the molecular classification of breast cancer, which divides it into four subtypes (Luminal A, Luminal B, HER2-enriched and Basal-like) is useful for predicting the benefits of treatment in patients with advanced hormone-sensitive breast cancer.

30 Mar 2021

Scientists estimate the amount of peanut protein that will elicit an allergic reaction

An estimated 6 million Americans may suffer from peanut allergies. Tiny amounts of peanut protein can lead to hives, itching, tingling in the mouth, shortness of breath or nausea within minutes.

26 Mar 2021

High-fiber diet can significantly alter the gut microbiome and nutrient intake

A short-term intervention in daily fiber consumption can significantly alter the gut microbiome and nutrient intake, according to a study led by University of California, Irvine researchers. The research was recently published by the American Society for Microbiology.

26 Mar 2021

Immunotherapy

Overview

Activation Immunotherapies

Immunotherapy and Helminthic Therapy

Suppression Immunotherapies

Feature Articles

Immunotherapy: Past, Present and Future

Adoptive T Cell Therapy Methodology

Adoptive T Cell Therapy Applications

Immunotherapy: The Future of Lung Cancer Treatment?

Latest Immunotherapy News and Research

Study shows how melanoma cells evade detection and destruction by immune cells

Increased incidence of melanoma in Utah points to overdiagnosis

A collaborative effort to evaluate treatment of liver and pancreatic tumors

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

New research could rescue failed immunotherapies for treating solid tumors

Phase 1 clinical trial to test a new, potential method against cancer

High expression of cell death genes may increase risk of early death from lung cancer

New software package employs deep-learning algorithms to analyze T-cell receptor sequencing data

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

Stem cell transplants offer long-term benefits for pediatric cancer patients receiving immunotherapy

Modest dietary changes and exercise can improve survival outcomes for young people with leukemia

Evidence-based clinical practice guideline aims to optimize PD-L1 lung tumor testing

Study confirms the predictive value of molecular classification of hormone-sensitive breast cancer

Scientists estimate the amount of peanut protein that will elicit an allergic reaction

High-fiber diet can significantly alter the gut microbiome and nutrient intake

AI study on aggressive form of cancer could improve patient outcomes

DAPK3 slows tumor growth by activating fierce-sounding STING pathway

Moffitt researchers use mathematical modeling to help explain outcomes of CAR T-cell therapy

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

Breath Analysis: How Could it Improve Healthcare and Diagnosis?

Advancing the Diagnosis and Treatment of Ovarian Cancer

World Health Day 2021 – “Building a fairer, healthier world”

Immunotherapy

Overview

Feature Articles

Immunotherapy: Past, Present and Future

Adoptive T Cell Therapy Methodology

Adoptive T Cell Therapy Applications

Immunotherapy: The Future of Lung Cancer Treatment?

Latest Immunotherapy News and Research

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