Immunotherapy

Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

What is Immunotherapy?

Immunotherapy is treatment that is designed to harness the ability of the body’s immune system to combat infection or disease. Immunotherapy might produce an immune response to disease or enhance the immune system’s resistance to active diseases such as cancer.

Activation Immunotherapies

Immunotherapy and Helminthic Therapy

Suppression Immunotherapies

Immunotherapy: past, present and future

Adoptive T Cell Therapy Methodology

Adoptive T Cell Therapy Applications

Immunotherapy: The Future of Lung Cancer Treatment?

Latest Immunotherapy News and Research

Study may help develop more effective personalized immunotherapy for cancer patients

New research from CU Cancer Center member Jing Hong Wang, MD, PhD, and recent University of Colorado Immunology program graduate Rachel Woolaver, PhD, may help researchers develop more effective personalized immunotherapy for cancer patients.

15 Jan 2021

Targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers

Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response.

15 Jan 2021

Study offers a differentiated patient-specific solution in minimal residual disease testing

Exact Sciences Corp. today announced that it has acquired a worldwide exclusive license to the proprietary TARDIS technology from the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.

15 Jan 2021

UTSW study uncovers a gene linked to growth of breast cancer

A team of UT Southwestern researchers has identified a gene involved in the growth of breast cancer, a finding that could lead to potential new targets for treatment.

12 Jan 2021

Advanced humanized mouse model helps better understand immunotherapy resistance in melanoma

Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for mast cells. These findings were published today in the journal Nature Communications.

12 Jan 2021

Study investigates effect of anti-CD45 RIT lymphodepletion on immune cell types

Oncotarget recently published "Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy" which reported that Chimeric antigen receptor T cell therapies, and adoptive cell therapy in general, represent one of the most promising anti-cancer strategies.

12 Jan 2021

ARID1A gene in ovarian cancer plays a role in the regulation of metabolism

Mutations that inactivate the ARID1A gene in ovarian cancer increase utilization of the glutamine amino acid making cancer cells dependent on glutamine metabolism, according to a study by The Wistar Institute published online in Nature Cancer.

12 Jan 2021

Researchers develop new technique to more efficiently isolate and identify rare T cells

Scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a technique that will enable researchers to more efficiently isolate and identify rare T cells that are capable of targeting viruses, cancer and other diseases.

12 Jan 2021

MDC researchers develop a potent weapon against lymphomas

MDC researchers have developed a new approach to CAR T-cell therapy. The team has shown in Nature Communications that the procedure is very effective, especially when it comes to fighting follicular lymphomas and chronic lymphocytic leukemia, the most common type of blood cancer in adults.

11 Jan 2021

Scientists gain new insight into how the immune system can be better used to destroy cancer cells

Scientists at the University of Southampton's Centre for Cancer Immunology have gained new insight into how the immune system can be better used to find and kill cancer cells.

8 Jan 2021

UCSF researchers discover a new way to control immune system's 'natural killer' cells

UC San Francisco scientists have discovered a new way to control the immune system's "natural killer" (NK) cells, a finding with implications for novel cell therapies and tissue implants that can evade immune rejection.

8 Jan 2021

Proteogenomics can help determine effective treatment for head and neck squamous cell carcinoma

Proteogenomic analysis may offer new insight into matching cancer patients with an effective therapy for their particular cancer.

7 Jan 2021

MD Anderson and Xencor to develop novel antibody therapeutics to treat cancer patients

The University of Texas MD Anderson Cancer Center and Xencor, Inc. today announced a strategic research collaboration and commercialization agreement to develop novel CD3 bispecific antibody therapeutics for the potential treatment of patients with cancer.

7 Jan 2021

Scientists develop a new method to study the molecular characteristics of T cells

UT Southwestern scientists have developed a new method to study the molecular characteristics of T cells, critical immune cells that recognize and attack invaders in the body such as viruses, bacteria, and cancer.

6 Jan 2021

Gut microbe may play a role in the development of breast cancers

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research from investigators with the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Jan 2021

Researchers reveal distinct molecular signature in tumor tissues of Black breast cancer patients

A Roswell Park Comprehensive Cancer Center team led by Christine Ambrosone, PhD, and Song Yao, PhD, has revealed a distinct molecular signature in the tumor tissues of Black patients with breast cancer.

5 Jan 2021

NCCN publishes new informational resources on health and wellness for cancer survivors

Today, the National Comprehensive Cancer Network announced the publication of new, free informational resources on health and wellness for cancer survivors.

5 Jan 2021

Researchers discover new metabolic vulnerability in a highly aggressive form of lung cancer

Researchers at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in a highly aggressive form of non-small cell lung cancer (NSCLC).

5 Jan 2021

Increased pollen counts may trigger symptom flares in patients with urologic chronic pelvic pain syndrome

As anyone living with hay fever can attest, days with high pollen counts can bring attacks of sneezing, nasal congestion and other allergy symptoms.

5 Jan 2021

Researchers discover protein crucial to T cell metabolism and anti-tumor immune response

Researchers at The University of Texas MD Anderson Cancer Center have discovered that a protein called NF-kappa B-inducing kinase (NIK) is essential for the shift in metabolic activity that occurs with T cell activation, making it a critical factor in regulating the anti-tumor immune response.

4 Jan 2021

Immunotherapy

Overview

Activation Immunotherapies

Immunotherapy and Helminthic Therapy

Suppression Immunotherapies

Feature Articles

Immunotherapy: past, present and future

Adoptive T Cell Therapy Methodology

Adoptive T Cell Therapy Applications

Immunotherapy: The Future of Lung Cancer Treatment?

Latest Immunotherapy News and Research

Study may help develop more effective personalized immunotherapy for cancer patients

Targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers

Study offers a differentiated patient-specific solution in minimal residual disease testing

UTSW study uncovers a gene linked to growth of breast cancer

Advanced humanized mouse model helps better understand immunotherapy resistance in melanoma

Study investigates effect of anti-CD45 RIT lymphodepletion on immune cell types

ARID1A gene in ovarian cancer plays a role in the regulation of metabolism

Researchers develop new technique to more efficiently isolate and identify rare T cells

MDC researchers develop a potent weapon against lymphomas

Scientists gain new insight into how the immune system can be better used to destroy cancer cells

UCSF researchers discover a new way to control immune system's 'natural killer' cells

Proteogenomics can help determine effective treatment for head and neck squamous cell carcinoma

MD Anderson and Xencor to develop novel antibody therapeutics to treat cancer patients

Scientists develop a new method to study the molecular characteristics of T cells

Gut microbe may play a role in the development of breast cancers

Researchers reveal distinct molecular signature in tumor tissues of Black breast cancer patients

NCCN publishes new informational resources on health and wellness for cancer survivors

Researchers discover new metabolic vulnerability in a highly aggressive form of lung cancer

Increased pollen counts may trigger symptom flares in patients with urologic chronic pelvic pain syndrome

Researchers discover protein crucial to T cell metabolism and anti-tumor immune response

A paper-based sensor for detecting COVID-19

Cadmium linked to more severe flu and pneumonia infections

Could neurological complications be common even in mild COVID-19?

Immunotherapy

Overview

Feature Articles

Immunotherapy: past, present and future

Adoptive T Cell Therapy Methodology

Adoptive T Cell Therapy Applications

Immunotherapy: The Future of Lung Cancer Treatment?

Latest Immunotherapy News and Research

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