Immunotherapy

Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

What is Immunotherapy?

Immunotherapy is a treatment that is designed to harness the ability of the body’s immune system to combat infection or disease.

Activation Immunotherapies

Suppression Immunotherapies

Immunotherapy: Past, Present and Future

Immunotherapy and Helminthic Therapy

Neoantigens' Role in Immunotherapy

Immunotherapy: The Future of Lung Cancer Treatment?

Adoptive T Cell Therapy Applications

Adoptive T Cell Therapy Methodology

Latest Immunotherapy News and Research

Study reveals how p53 mutations cause tumors to resist cancer immunotherapy

Immune checkpoint blockade (ICB) therapy has transformed cancer treatment, but many tumors remain resistant.

22 Jul 2026

UVA researchers develop a new experimental approach to target glioblastoma

University of Virginia Comprehensive Cancer Center scientists have developed a promising new experimental approach to targeting glioblastoma, the most common and deadliest brain cancer.

22 Jul 2026

Wistar scientists develop new bispecific T cell engager to target ovarian cancer

Wistar scientists have developed a new type of bispecific T cell engager, or BTE, that is effective against ovarian cancer in preclinical studies.

21 Jul 2026

City of Hope launches trial to map how tumors change during immunotherapy resistance

City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation's top cancer centers by U.S. News & World Report, has opened an innovative Phase 2 clinical trial designed to map how tumors change as they begin to resist immunotherapy, treatment that improves the immune system's ability to fight disease.

21 Jul 2026

Mount Sinai establishes new autoimmunity center with $5 million gift

A $5 million gift from philanthropists Judith and Stewart Colton will establish a Colton Center for Autoimmunity within the Marc and Jennifer Lipschultz Precision Immunology Institute (PrIISM) at the Icahn School of Medicine at Mount Sinai.

21 Jul 2026

Unlocking the untapped 90%: Membrane protein purification as a three hours routine workflow

Automated, detergent-free purification preserves native membrane protein structure while supporting more reliable target validation workflows.

From Analytik Jena 21 Jul 2026

Thymus hormone identified as key player in reversing age-related inflammation

Chronic, low-grade inflammation in the body-a phenomenon known as "inflammaging" because it increases with age-has been linked to many of today's leading causes of illness and death, including cancer, heart disease, metabolic conditions and neurodegenerative diseases.

21 Jul 2026

New strategy boosts immune attack against pancreatic cancer

Researchers from the University of Minnesota Medical School have identified why pancreatic cancer is difficult for the immune system to recognize and attack, paving the way for a new approach to improve immunotherapy.

20 Jul 2026

Exercise oncology could unlock new therapeutic pathways against cancer

Regular exercise is associated with improved outcomes for many patients with cancer, yet those with advanced disease may be unable to participate in exercise-based interventions.

20 Jul 2026

Specialized blood vessels enable effective immune defense against cancer metastases

It has long been suspected that endothelial cells, the specialized cells lining the inner walls of blood vessels, play a key role in determining how the body’s immune system responds to tumors.

20 Jul 2026

KAIST study opens a new avenue for treating intractable brain tumors

Researchers have uncovered a clue to why immune checkpoint inhibitors-cancer therapies that release the immune "brakes" exploited by tumors to evade attack-show limited efficacy in some brain tumors.

19 Jul 2026

Experimental drug shows promise against NRAS-driven melanoma

A research team from Huntsman Cancer Institute at the University of Utah (the U) reports that a groundbreaking pathway-targeted therapy could be an effective treatment for certain melanoma patients and fill an unmet clinical need for patients with advanced disease.

16 Jul 2026

Targeting ZBP1 may overcome cancer immunotherapy resistance

A new Review published in the open-access journal Ferroptosis and Oxidative Stress highlights Z-nucleic acid-binding protein 1 (ZBP1) as an emerging innate immune sensor that converts genomic stress into potent antitumor immunity.

16 Jul 2026

Specialized dendritic cells found to coordinate antitumor immunity

Researchers at the Icahn School of Medicine at Mount Sinai have identified the immune cell that acts as the architect and coordinator of powerful immune hubs that form inside tumors and plays a key role in antitumor immunity.

16 Jul 2026

New biological feedback loop helps the immune system attack colorectal cancers

A subset of cancers, known as microsatellite instability (MSI) and deficient DNA mismatch repair (dMMR) cancers, are more visible to the immune system than others.

16 Jul 2026

Experimental KRAS vaccine safely generates durable immune response against pancreatic cancer

Researchers at the Johns Hopkins Kimmel Cancer Center and its Skip Viragh Center for Pancreatic Cancer report that an experimental vaccine targeting mutant KRAS, one of the most common genetic drivers of pancreatic cancer, was safe and generated durable immune responses aimed at preventing the cancer in people at high risk.

16 Jul 2026

AI model predicts effective immunotherapy combinations for liver cancer

Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to predict which patients with a primary liver cancer called hepatocellular carcinoma (HCC) would most benefit from combination treatment using immunotherapy and a targeted therapy that blocks the growth signals that the tumor depends on.

15 Jul 2026