Immunotherapy

Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

What is Immunotherapy?

Immunotherapy is a treatment that is designed to harness the ability of the body’s immune system to combat infection or disease.

Immunotherapy: The Future of Lung Cancer Treatment?

Activation Immunotherapies

Suppression Immunotherapies

Adoptive T Cell Therapy Methodology

Immunotherapy: Past, Present and Future

Adoptive T Cell Therapy Applications

Immunotherapy and Helminthic Therapy

Neoantigens' Role in Immunotherapy

Latest Immunotherapy News and Research

New molecule offers a more targeted and potent immunotherapy

A newly developed molecule brings together two powerful immunotherapy strategies in one treatment. Researchers at the University of Basel and University Hospital Basel, Switzerland, have demonstrated that this fusion protein can both block the "do not attack" signal used by cancer cells and selectively activate tumor-fighting immune cells. This dual action could pave the way for more effective cancer therapies with fewer side effects.

18 Sep 2025

The 15th AACR cancer progress report highlights scientific advances

The American Association for Cancer Research (AACR) released the 15th edition of its annual Cancer Progress Report. A cornerstone of the AACR's educational and advocacy efforts, this comprehensive report provides the latest statistics on cancer incidence, mortality, and survivorship and highlights how federal investments in basic, translational, and clinical cancer research and cancer-related population sciences have led to impressive scientific advances that are improving health and saving lives.

17 Sep 2025

New findings show lymph nodes educate T cells to combat disease

A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the cellular and molecular interactions revealing how lymph nodes play a crucial role in the fight against chronic infection and cancer.

17 Sep 2025

CRISPR-GPT helps scientists to generate designs, analyze data and troubleshoot design flaws

Stanford Medicine researchers have developed an artificial intelligence tool to help scientists better plan gene-editing experiments.

16 Sep 2025

Triple negative breast cancer exploits lymph node niches to block immune defense

In almost all solid tumors - i.e. cancers with a solid tissue structure - the detection of tumor cells in the lymph nodes is considered a decisive marker for the progression of the disease.

16 Sep 2025

Targeting telomere damage offers new path to boost cancer immunotherapy

Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on mitochondria, the cell's energy factories, leading to T cell exhaustion and poor cancer outcomes.

10 Sep 2025

Lung tumors rewire immune cells in the bone marrow before they reach cancer sites

Lung tumors don't just evade the immune system. They reshape it at its source. Researchers from the Icahn School of Medicine at Mount Sinai and collaborators report in the September 10 online issue of Nature that tumors rewire immune cells in the bone marrow before they even reach the cancer, suggesting a new target to enhance the durability of current immunotherapy

10 Sep 2025

Bottlebrush particles deliver large range of chemotherapy drugs directly to tumor cells

Using tiny particles shaped like bottlebrushes, MIT chemists have found a way to deliver a large range of chemotherapy drugs directly to tumor cells.

10 Sep 2025

Combination immunotherapy prior to surgery shows encouraging results in mesothelioma

Results from an early phase clinical trial presented this week at the World Conference on Lung Cancer Meeting in Barcelona, Spain, and published in the Nature Medicine journal today [Monday, 8th September 2025] show that patients with mesothelioma - a rare cancer of the lining of the lung that may be caused by exposure to asbestos - who received a combination of two immunotherapy drugs, nivolumab and ipilimumab, before surgery had successful surgeries and encouraging early outcomes.

9 Sep 2025

IFITM3 found to be critical regulator of immunotherapy sensitivity in small cell lung cancer

New research presented identifies interferon-induced transmembrane protein 3 (IFITM3) as a critical regulator of immunotherapy sensitivity in small cell lung cancer (SCLC), offering a promising new avenue for overcoming resistance to PD-1/PD-L1 checkpoint blockade.

9 Sep 2025

Monitoring ctDNA can personalize the use of consolidation immunotherapy in patients with LS-SCLC

A new study presented at the International Association for the Study of Lung Cancer 2025 World Conference on Lung Cancer (WCLC) demonstrates that monitoring circulating tumor DNA (ctDNA) can refine and personalize the use of consolidation immunotherapy in patients with limited-stage small cell lung cancer (LS-SCLC).

9 Sep 2025

New strategy for difficult-to-treat mesothelioma: Immunotherapy and ctDNA insights

People with operable diffuse pleural mesothelioma may benefit from immunotherapy before and after surgery, based on results of a clinical trial exploring the sequence of treatment and the role of surgery for this difficult to treat cancer.

8 Sep 2025

Tarlatamab and anti-PD-L1 therapy combination demonstrates manageable safety profile in first-line ES-SCLC

Clinical data presented today demonstrates the combination of tarlatamab with anti-PD-L1 therapy as first-line maintenance has an acceptable safety profile and resulted in unprecedented overall survival in patients with extensive-stage small cell lung cancer (ES-SCLC).

8 Sep 2025

HypoRT with concurrent chemotherapy reduces treatment time and toxicity for patients with LS-SCLC

A multi-center, randomized phase III trial has found that a three-week hypofractionated radiotherapy (HypoRT) schedule with concurrent chemotherapy provides similar survival outcomes and reduced toxicity compared to the standard six-week conventional fractionated radiotherapy (ConvRT) schedule for patients with limited-stage small cell lung cancer (LS-SCLC).

8 Sep 2025

Adjuvant chemo-immunotherapy may benefit patients with resected stage IB–IIIA NSCLC, trial suggests

Interim results from the NADIM ADJUVANT Phase III trial, led by the Spanish Lung Cancer Group (GECP), suggest that adjuvant chemo-immunotherapy may reduce the risk of recurrence in patients with completely resected stage IB–IIIA non-small cell lung cancer (NSCLC) while maintaining an acceptable safety profile.

8 Sep 2025

New drug candidate STF 1623 activates innate immunity in solid tumors

Cancer immunotherapy, which primes the body's immune system to fight off tumors, has historically focused on harnessing T cells' natural ability to recognize and attack cancer cells.

5 Sep 2025

WHO expands essential medicines lists with new cancer and diabetes treatments

Today, the World Health Organization (WHO) has released updated editions of its Model Lists of Essential Medicines (EML) and Essential Medicines for Children (EMLc), adding new treatments for various types of cancer and for diabetes with associated comorbidities such as obesity.

5 Sep 2025

Immunotherapy

Overview

Immunotherapy: The Future of Lung Cancer Treatment?

Activation Immunotherapies

Suppression Immunotherapies

Feature Articles

Adoptive T Cell Therapy Methodology

Immunotherapy: Past, Present and Future

Adoptive T Cell Therapy Applications

Immunotherapy and Helminthic Therapy

Neoantigens' Role in Immunotherapy

Latest Immunotherapy News and Research

New molecule offers a more targeted and potent immunotherapy

The 15th AACR cancer progress report highlights scientific advances

New findings show lymph nodes educate T cells to combat disease

CRISPR-GPT helps scientists to generate designs, analyze data and troubleshoot design flaws

Triple negative breast cancer exploits lymph node niches to block immune defense

Targeting telomere damage offers new path to boost cancer immunotherapy

Lung tumors rewire immune cells in the bone marrow before they reach cancer sites

Bottlebrush particles deliver large range of chemotherapy drugs directly to tumor cells

Combination immunotherapy prior to surgery shows encouraging results in mesothelioma

IFITM3 found to be critical regulator of immunotherapy sensitivity in small cell lung cancer

Monitoring ctDNA can personalize the use of consolidation immunotherapy in patients with LS-SCLC

New strategy for difficult-to-treat mesothelioma: Immunotherapy and ctDNA insights

Tarlatamab and anti-PD-L1 therapy combination demonstrates manageable safety profile in first-line ES-SCLC

HypoRT with concurrent chemotherapy reduces treatment time and toxicity for patients with LS-SCLC

Adjuvant chemo-immunotherapy may benefit patients with resected stage IB–IIIA NSCLC, trial suggests

New drug candidate STF 1623 activates innate immunity in solid tumors

WHO expands essential medicines lists with new cancer and diabetes treatments

Targeting metabolic reprogramming to overcome immune suppression in head and neck cancer

Oncolytic viruses integrated with immunotherapy for next-generation cancer treatment

Targeting ADAR1 offers new hope against glioblastoma

eBook: Cell-based technologies in drug discovery and Immunotherapy eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Immunotherapy

Overview

Feature Articles

Adoptive T Cell Therapy Methodology

Immunotherapy: Past, Present and Future

Adoptive T Cell Therapy Applications

Immunotherapy and Helminthic Therapy

Neoantigens' Role in Immunotherapy

Latest Immunotherapy News and Research

eBook: Cell-based technologies in drug discovery and Immunotherapy eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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