Immunotherapy News and Research

Latest Immunotherapy News and Research

Mitotane’s role in the management of adrenocortical carcinoma

Adrenocortical carcinoma (ACC) is a rare but aggressive malignancy with high postoperative recurrence rates and poor prognosis. Mitotane remains the only approved agent for ACC, exerting antitumor effects by disrupting mitochondrial integrity, inhibiting steroidogenic enzymes, and interfering with cholesterol metabolism.

21 Jan 2026

Landmark UK study supports nationwide screening for childhood type 1 diabetes

A landmark UK study involving tens of thousands of families has shown that childhood screening for type 1 diabetes is effective, laying the groundwork for a UK-wide childhood screening program.

20 Jan 2026

ELRIG announces Drs Stephen Ward and Annarita Miccio as keynote speakers for Cell and Gene Therapy 2026

ELRIG, a not-for-profit, volunteer-led organization dedicated to the global drug discovery community, today announced the keynote speakers for Cell and Gene Therapy 2026. Drs Stephen Ward (Cell and Gene Therapy Catapult) and Annarita Miccio (Imagine Institute) will lead the inaugural two-day event taking place at Hinxton Hall in Cambridge, UK from 9-10 March.

20 Jan 2026

Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments

Oncologists have achieved some immune system responses in patients with pancreatic cancers using various combinations of vaccines and immune checkpoint inhibitor drugs, but it's not always clear which therapy is inducing what type of response.

16 Jan 2026

Investigational cancer vaccine shows early promise for cancer prevention in Lynch syndrome

The investigational cancer vaccine, NOUS-209, was found to safely stimulate the immune system to target precancerous and cancerous cells in individuals with Lynch Syndrome (LS), according to a study from researchers at The University of Texas MD Anderson Cancer Center.

16 Jan 2026

Targeting microRNA communication reverses pancreatic cancer's immune suppression

In a unique finding, researchers at Georgetown's Lombardi Comprehensive Cancer Center discovered that when pancreatic cancer cells send out tiny particles that are packed with certain microRNA molecules, nearby immune cells called macrophages are reprogrammed to help the tumor grow instead of engaging in their regular role of fighting the tumor.

16 Jan 2026

Bacterial metabolite enhances immune checkpoint therapy against lung cancer

UF Health Cancer Institute researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.

14 Jan 2026

Lund researchers create "recipe book" for reprogramming immune cells to fight disease

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the "recipe" for the transformation.

14 Jan 2026

DLL3 on circulating tumor cells predicts tarlatamab success in lung cancer

A team led by investigators at the Mass General Brigham Cancer Institute has discovered that a particular marker on tumor cells circulating in the blood indicates whether a patient with lung cancer will experience a lasting response to a newly approved immunotherapy called tarlatamab.

14 Jan 2026

Novel antibody shows promise in overcoming resistance to cancer immunotherapy

According to a Phase I study led by researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Medicine, the novel monoclonal antibody linavonkibart demonstrated the potential to overcome treatment resistance to anti-PD-1 immune checkpoint inhibitors in multiple cancer types.

13 Jan 2026

Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial

A recent publication in Nature Medicine describes a novel immunotherapy targeting pancreatic cancer that has shown promising results in a first in-human phase 1/2 trial.

13 Jan 2026

Study identifies PUF60 as a critical vulnerability in triple negative breast cancer

Researchers at University of California San Diego have identified a previously unrecognized treatment target for triple‑negative breast cancer (TNBC), the most aggressive subtype of breast cancer.

12 Jan 2026

CNIO study identifies genes linked to pancreatic cancer risk and prognosis

A new study by the National Cancer Research Centre (CNIO) has identified several sets of genes related to the predisposition to develop pancreatic ductal adenocarcinoma (the most common type of pancreatic cancer), as well as the prognosis of the disease once it has appeared.

12 Jan 2026

Ultrasound-responsive nanocatchers enable precise in-situ tumor antigen capture

Professor Zhaohui Tang and Associate Professor Zhilin Liu from the team of Professor Xuesi Chen at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, developed ultrasound-responsive in-situ antigen nanocatchers (S-nanocatchers), achieving precise spatiotemporal capture of tumor antigens and controllable acquisition of in-situ vaccines.

9 Jan 2026

Durvalumab extends survival in small cell lung cancer but raises cost concerns

A new study suggests that the immune checkpoint inhibitor, durvalumab, may offer new treatment options for patients living with small cell lung cancer (SCLC).

9 Jan 2026

Single-cell analysis illuminates myeloma immune landscape

Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients with multiple myeloma, a blood cancer that, while treatable, remains incurable.

9 Jan 2026

Targeting IDO1 for cancer: Novel degraders show promise in preclinical studies

Cancer cells employ a variety of strategies to evade the immune system, and modern immunotherapies aim precisely at these escape mechanisms.

9 Jan 2026

Clonal hematopoiesis linked to increased heart disease risk in cancer patients receiving treatment

About 1 in 5 patients with cancer who undergo genetic testing are incidentally found to have mutations in their blood called clonal hematopoiesis of indeterminate potential (CHIP).

8 Jan 2026

UVA researcher wins $700,000 for promising ovarian cancer research

Promising ovarian cancer research by Melanie Rutkowski, PhD, at the University of Virginia Comprehensive Cancer Center has won $700,000 in support from the Victoria's Secret Global Fund for Women's Cancers in partnership with Pelotonia and AACR, the American Association for Cancer Research.

8 Jan 2026

Recent advances in CAR-NK cell therapy could revolutionze cancer treatment

Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, manufacturing complexity, and limited effectiveness against solid tumors.

8 Jan 2026

Immunotherapy News and Research

Latest Immunotherapy News and Research

Mitotane’s role in the management of adrenocortical carcinoma

Landmark UK study supports nationwide screening for childhood type 1 diabetes

ELRIG announces Drs Stephen Ward and Annarita Miccio as keynote speakers for Cell and Gene Therapy 2026

Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments

Investigational cancer vaccine shows early promise for cancer prevention in Lynch syndrome

Targeting microRNA communication reverses pancreatic cancer's immune suppression

Bacterial metabolite enhances immune checkpoint therapy against lung cancer

Lund researchers create "recipe book" for reprogramming immune cells to fight disease

DLL3 on circulating tumor cells predicts tarlatamab success in lung cancer

Novel antibody shows promise in overcoming resistance to cancer immunotherapy

Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial

Study identifies PUF60 as a critical vulnerability in triple negative breast cancer

CNIO study identifies genes linked to pancreatic cancer risk and prognosis

Ultrasound-responsive nanocatchers enable precise in-situ tumor antigen capture

Durvalumab extends survival in small cell lung cancer but raises cost concerns

Single-cell analysis illuminates myeloma immune landscape

Targeting IDO1 for cancer: Novel degraders show promise in preclinical studies

Clonal hematopoiesis linked to increased heart disease risk in cancer patients receiving treatment

UVA researcher wins $700,000 for promising ovarian cancer research

Recent advances in CAR-NK cell therapy could revolutionze cancer treatment

Event guide: 7th Allogeneic Cell Therapies Summit eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Immunotherapy News and Research

Latest Immunotherapy News and Research

Event guide: 7th Allogeneic Cell Therapies Summit eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Newsletters you may be interested in