Immunotherapy News and Research

Latest Immunotherapy News and Research

AI-designed proteins bring personalized cancer treatment within reach

Precision cancer treatment on a larger scale is moving closer after researchers have developed an AI platform that can tailor protein components and arm the patient's immune cells to fight cancer.

24 Jul 2025

Blocking nutrient scavenging weakens pancreatic tumor defenses

Cancer cells and tumors do not exist in a vacuum. Far from the isolation and self-sufficiency of the fictional Wakanda, tumors develop in and alter the nearby milieu of immune cells, connective tissue, blood vessels and a sea of proteins and carbohydrates that provide structure and other supportive functions.

24 Jul 2025

Salk researcher awarded funding to boost immunotherapy for pancreatic cancer

Salk Institute Professor Diana Hargreaves was named a 2025 All-Star Translational Award Program grantee by the V Foundation for Cancer Research.

24 Jul 2025

Different anti-PD-L1 antibodies show varied results in tumor growth inhibition

Immune checkpoint inhibitors (ICIs), a powerful form of immunotherapy, have revolutionized cancer treatment by unleashing the body's own immune system to fight tumors.

24 Jul 2025

Innovative immunotherapy trial opens for newly-diagnosed glioblastoma patients

A UCL-sponsored clinical trial for patients newly diagnosed with glioblastoma, an aggressive form of brain cancer, has opened at UCLH's National Hospital for Neurology and Neurosurgery and Clinical Research Facility, in memory of Baroness Margaret McDonagh.

24 Jul 2025

STRIDE immunotherapy sets new benchmark for survival in advanced liver cancer

A new exploratory analysis of the HIMALAYA phase III trial involving patients with unresectable hepatocellular carcinoma (uHCC, an advanced liver cancer that could not be treated with surgery or other localized treatments) has shown that one in five (19.6%) participants treated with STRIDE (Single Tremelimumab Regular Interval Durvalumab) a combination of two immunotherapies, remained alive after five years of follow-up versus one in 10 (9.4%) participants treated with sorafenib, a standard treatment for uHCC when the study was designed.

23 Jul 2025

Long-term air pollution exposure triggers allergic immune responses in the lungs

Air pollution is a global health concern, with over 90% of the world's population breathing air that exceeds World Health Organization safety standards.

23 Jul 2025

New approach doubles chemotherapy effectiveness by targeting cancer cell memory

In a wholly new approach to cancer treatment, Northwestern University biomedical engineers have doubled the effectiveness of chemotherapy in animal experiments.

22 Jul 2025

Radiation primes the immune system to attack lung tumors resistant to immunotherapy

By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Netherlands Cancer Institute.

22 Jul 2025

Toti-N-Seq breakthrough enables universal and scalable single-cell profiling

The rapid advancement of single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) has opened unprecedented windows into cellular diversity, yet existing methods for multiplexing samples struggle with scalability and accuracy.

22 Jul 2025

Microbial signals rewire immunity in esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) is a deadly cancer with particularly high prevalence in East Asia.

21 Jul 2025

Cuproptosis offers new hope for treating inflammatory bowel disease and colorectal cancer

Cuproptosis represents a novel mechanism of cell death characterized by intracellular copper ion accumulation.

18 Jul 2025

New mRNA vaccine strategy awakens immune system to fight cancer

An experimental mRNA vaccine boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system against cancer.

18 Jul 2025

New monoclonal antibody enhances immune response by selectively targeting Tregs

A new research paper was published in Volume 16 of Oncotarget on July 9, 2025, titled "A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment."

17 Jul 2025

Prestigious Stephenson Scholar Grants support cutting-edge pancreatic cancer studies

The Stephenson Global Pancreatic Cancer Research Institute and its partner City of Hope, one of the country's largest and most advanced cancer research and treatment organizations, today announced the six inaugural recipients of the prestigious Stephenson Scholar Grants, awarding $5.25 million to support high-impact research aimed at transforming the understanding, early detection and treatment of pancreatic cancer.

16 Jul 2025

Fred Hutch leads national study on multi-cancer detection blood tests

Fred Hutch Cancer Center is leading the newly launched Vanguard Study, a national study of a new type of blood test that screens for several different cancers called multi-cancer detection (MCD) tests.

16 Jul 2025

Research unravels the immune secrets of a cured pediatric rhabdoid tumor

Although relatively rare, many childhood cancers remain life-threatening and lack effective personalized treatments. Rhabdoid tumors are among these fatal cancers and can develop in various tissues and organs.

16 Jul 2025

WEE1 identified as a key driver of immune resistance in cancer

Immune checkpoints are regulatory proteins that prevent the immune system from attacking healthy tissues.

15 Jul 2025

Nasal antibody spray shields mice from pollen-triggered allergies and asthma

Intranasal delivery of a monoclonal IgG1 antibody targeting mugwort pollen protected mice from allergic rhinitis and asthma symptoms, without lowering systemic IgE levels. This localized, non-invasive approach dampened Th2 inflammation and preserved healthy airway tissue in sensitized mice.

14 Jul 2025